FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807241689> ?p ?o ?g. }

• W2807241689 endingPage "E27" @default.
• W2807241689 startingPage "E23" @default.
• W2807241689 abstract ": Here we report the case of a 20-year-old patient who was diagnosed in 2002 with a metastatic colorectal cancer (CRC). He achieved a complete response under cetuximab-based therapy and remains without disease recurrence until now while chemotherapy was discontinued in 2009. The tumor exhibited high level of epidermal growth factor receptor (EGFR) amplification, no mutation in KRAS, NRAS or BRAF genes and a microsatellite-stable (MSS) phenotype. Intriguingly this young patient was carrying a monoallelic germline mutation of MUTYH that was associated with an inactivation of the second allele by loss of heterozygosity on tumor DNA. Moreover, this mutation was associated with a specific mutational signature on tumor level characterized by C > A single base substitutions and a higher mutational load than usually observed in MSS neoplasms. This case report paves the way for further researches on MUTYH-associated cancers’ sensitivity to anticancer therapies." @default.
• W2807241689 created "2018-06-13" @default.
• W2807241689 creator A5002693893 @default.
• W2807241689 creator A5026178746 @default.
• W2807241689 creator A5049661683 @default.
• W2807241689 creator A5064602870 @default.
• W2807241689 creator A5079480540 @default.
• W2807241689 creator A5089818289 @default.
• W2807241689 date "2018-08-01" @default.
• W2807241689 modified "2023-10-18" @default.
• W2807241689 title "Unresectable metastatic colorectal cancer patient cured with cetuximab-based chemotherapy: a case report with new molecular insights" @default.
• W2807241689 cites W2000591164 @default.
• W2807241689 cites W2011492006 @default.
• W2807241689 cites W2026895762 @default.
• W2807241689 cites W2061628403 @default.
• W2807241689 cites W2071354778 @default.
• W2807241689 cites W2094777367 @default.
• W2807241689 cites W2122885616 @default.
• W2807241689 cites W2142564546 @default.
• W2807241689 cites W2148300747 @default.
• W2807241689 cites W2164837623 @default.
• W2807241689 cites W2168377135 @default.
• W2807241689 cites W2470575266 @default.
• W2807241689 cites W2581568937 @default.
• W2807241689 cites W2757929633 @default.
• W2807241689 cites W2770647635 @default.
• W2807241689 doi "https://doi.org/10.21037/jgo.2018.05.10" @default.
• W2807241689 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6087863" @default.
• W2807241689 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30151276" @default.
• W2807241689 hasPublicationYear "2018" @default.
• W2807241689 type Work @default.
• W2807241689 sameAs 2807241689 @default.
• W2807241689 citedByCount "7" @default.
• W2807241689 countsByYear W28072416892018 @default.
• W2807241689 countsByYear W28072416892019 @default.
• W2807241689 countsByYear W28072416892020 @default.
• W2807241689 countsByYear W28072416892021 @default.
• W2807241689 countsByYear W28072416892022 @default.
• W2807241689 countsByYear W28072416892023 @default.
• W2807241689 crossrefType "journal-article" @default.
• W2807241689 hasAuthorship W2807241689A5002693893 @default.
• W2807241689 hasAuthorship W2807241689A5026178746 @default.
• W2807241689 hasAuthorship W2807241689A5049661683 @default.
• W2807241689 hasAuthorship W2807241689A5064602870 @default.
• W2807241689 hasAuthorship W2807241689A5079480540 @default.
• W2807241689 hasAuthorship W2807241689A5089818289 @default.
• W2807241689 hasBestOaLocation W28072416891 @default.
• W2807241689 hasConcept C104317684 @default.
• W2807241689 hasConcept C121608353 @default.
• W2807241689 hasConcept C126322002 @default.
• W2807241689 hasConcept C13514818 @default.
• W2807241689 hasConcept C141496672 @default.
• W2807241689 hasConcept C143589142 @default.
• W2807241689 hasConcept C143998085 @default.
• W2807241689 hasConcept C180754005 @default.
• W2807241689 hasConcept C21790070 @default.
• W2807241689 hasConcept C2776694085 @default.
• W2807241689 hasConcept C2779438470 @default.
• W2807241689 hasConcept C2779998722 @default.
• W2807241689 hasConcept C2781187634 @default.
• W2807241689 hasConcept C501734568 @default.
• W2807241689 hasConcept C502942594 @default.
• W2807241689 hasConcept C526805850 @default.
• W2807241689 hasConcept C54355233 @default.
• W2807241689 hasConcept C71924100 @default.
• W2807241689 hasConcept C86803240 @default.
• W2807241689 hasConceptScore W2807241689C104317684 @default.
• W2807241689 hasConceptScore W2807241689C121608353 @default.
• W2807241689 hasConceptScore W2807241689C126322002 @default.
• W2807241689 hasConceptScore W2807241689C13514818 @default.
• W2807241689 hasConceptScore W2807241689C141496672 @default.
• W2807241689 hasConceptScore W2807241689C143589142 @default.
• W2807241689 hasConceptScore W2807241689C143998085 @default.
• W2807241689 hasConceptScore W2807241689C180754005 @default.
• W2807241689 hasConceptScore W2807241689C21790070 @default.
• W2807241689 hasConceptScore W2807241689C2776694085 @default.
• W2807241689 hasConceptScore W2807241689C2779438470 @default.
• W2807241689 hasConceptScore W2807241689C2779998722 @default.
• W2807241689 hasConceptScore W2807241689C2781187634 @default.
• W2807241689 hasConceptScore W2807241689C501734568 @default.
• W2807241689 hasConceptScore W2807241689C502942594 @default.
• W2807241689 hasConceptScore W2807241689C526805850 @default.
• W2807241689 hasConceptScore W2807241689C54355233 @default.
• W2807241689 hasConceptScore W2807241689C71924100 @default.
• W2807241689 hasConceptScore W2807241689C86803240 @default.
• W2807241689 hasIssue "4" @default.
• W2807241689 hasLocation W28072416891 @default.
• W2807241689 hasLocation W28072416892 @default.
• W2807241689 hasLocation W28072416893 @default.
• W2807241689 hasLocation W28072416894 @default.
• W2807241689 hasOpenAccess W2807241689 @default.
• W2807241689 hasPrimaryLocation W28072416891 @default.
• W2807241689 hasRelatedWork W2049754458 @default.
• W2807241689 hasRelatedWork W2066082532 @default.
• W2807241689 hasRelatedWork W2171311886 @default.
• W2807241689 hasRelatedWork W2435704186 @default.
• W2807241689 hasRelatedWork W2599556919 @default.
• W2807241689 hasRelatedWork W2768688354 @default.

• next