FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807324669> ?p ?o ?g. }

• W2807324669 endingPage "142" @default.
• W2807324669 startingPage "142" @default.
• W2807324669 abstract "The modification of the cancer classification system aimed to improve the classical anatomy-based tumor, node, metastasis (TNM) staging by considering tumor biology, which is associated with patient prognosis, because such information provides additional precision and flexibility.We previously developed an mRNA expression-based single patient classifier (SPC) algorithm that could predict the prognosis of patients with stage II/III gastric cancer. We also validated its utilization in clinical settings. The prognostic single patient classifier (pSPC) differentiates based on 3 prognostic groups (low-, intermediate-, and high-risk), and these groups were considered as independent prognostic factors along with TNM stages. We evaluated whether the modified TNM staging system based on the pSPC has a better prognostic performance than the TNM 8th edition staging system. The data of 652 patients who underwent gastrectomy with curative intent for gastric cancer between 2000 and 2004 were evaluated. Furthermore, 2 other cohorts (n=307 and 625) from a previous study were assessed. Thus, 1,584 patients were included in the analysis. To modify the TNM staging system, one-grade down-staging was applied to low-risk patients according to the pSPC in the TNM 8th edition staging system; for intermediate- and high-risk groups, the modified TNM and TNM 8th edition staging systems were identical.Among the 1,584 patients, 187 (11.8%), 664 (41.9%), and 733 (46.3%) were classified into the low-, intermediate-, and high-risk groups, respectively, according to the pSPC. pSPC prognoses and survival curves of the overall population were well stratified, and the TNM stage-adjusted hazard ratios of the intermediate- and high-risk groups were 1.96 (95% confidence interval [CI], 1.41-2.72; P<0.001) and 2.54 (95% CI, 1.84-3.50; P<0.001), respectively. Using Harrell's C-index, the prognostic performance of the modified TNM system was evaluated, and the results showed that its prognostic performance was better than that of the TNM 8th edition staging system in terms of overall survival (0.635 vs. 0.620, P<0.001).The pSPC-modified TNM staging is an alternative staging system for stage II/III gastric cancer." @default.
• W2807324669 created "2018-06-13" @default.
• W2807324669 creator A5000246711 @default.
• W2807324669 creator A5018242338 @default.
• W2807324669 creator A5028668097 @default.
• W2807324669 creator A5030930195 @default.
• W2807324669 creator A5052817996 @default.
• W2807324669 creator A5057610578 @default.
• W2807324669 creator A5061523629 @default.
• W2807324669 creator A5062494186 @default.
• W2807324669 creator A5088672821 @default.
• W2807324669 creator A5091270075 @default.
• W2807324669 date "2018-01-01" @default.
• W2807324669 modified "2023-10-10" @default.
• W2807324669 title "Modification of the TNM Staging System for Stage II/III Gastric Cancer Based on a Prognostic Single Patient Classifier Algorithm" @default.
• W2807324669 cites W1757407923 @default.
• W2807324669 cites W1985213644 @default.
• W2807324669 cites W1988186463 @default.
• W2807324669 cites W2049397238 @default.
• W2807324669 cites W2074703669 @default.
• W2807324669 cites W2110263577 @default.
• W2807324669 cites W2126547130 @default.
• W2807324669 cites W2147915707 @default.
• W2807324669 cites W2152407292 @default.
• W2807324669 cites W2165982376 @default.
• W2807324669 cites W2293692119 @default.
• W2807324669 cites W2502134830 @default.
• W2807324669 cites W2592337042 @default.
• W2807324669 cites W2593719389 @default.
• W2807324669 cites W2597872842 @default.
• W2807324669 cites W2789563241 @default.
• W2807324669 cites W4238211179 @default.
• W2807324669 doi "https://doi.org/10.5230/jgc.2018.18.e14" @default.
• W2807324669 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6026714" @default.
• W2807324669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29984064" @default.
• W2807324669 hasPublicationYear "2018" @default.
• W2807324669 type Work @default.
• W2807324669 sameAs 2807324669 @default.
• W2807324669 citedByCount "10" @default.
• W2807324669 countsByYear W28073246692019 @default.
• W2807324669 countsByYear W28073246692020 @default.
• W2807324669 countsByYear W28073246692021 @default.
• W2807324669 crossrefType "journal-article" @default.
• W2807324669 hasAuthorship W2807324669A5000246711 @default.
• W2807324669 hasAuthorship W2807324669A5018242338 @default.
• W2807324669 hasAuthorship W2807324669A5028668097 @default.
• W2807324669 hasAuthorship W2807324669A5030930195 @default.
• W2807324669 hasAuthorship W2807324669A5052817996 @default.
• W2807324669 hasAuthorship W2807324669A5057610578 @default.
• W2807324669 hasAuthorship W2807324669A5061523629 @default.
• W2807324669 hasAuthorship W2807324669A5062494186 @default.
• W2807324669 hasAuthorship W2807324669A5088672821 @default.
• W2807324669 hasAuthorship W2807324669A5091270075 @default.
• W2807324669 hasBestOaLocation W28073246692 @default.
• W2807324669 hasConcept C121608353 @default.
• W2807324669 hasConcept C126322002 @default.
• W2807324669 hasConcept C126838900 @default.
• W2807324669 hasConcept C143998085 @default.
• W2807324669 hasConcept C146357865 @default.
• W2807324669 hasConcept C151730666 @default.
• W2807324669 hasConcept C154945302 @default.
• W2807324669 hasConcept C2776808855 @default.
• W2807324669 hasConcept C2779013556 @default.
• W2807324669 hasConcept C2780325254 @default.
• W2807324669 hasConcept C2993415550 @default.
• W2807324669 hasConcept C41008148 @default.
• W2807324669 hasConcept C71924100 @default.
• W2807324669 hasConcept C86803240 @default.
• W2807324669 hasConcept C95623464 @default.
• W2807324669 hasConceptScore W2807324669C121608353 @default.
• W2807324669 hasConceptScore W2807324669C126322002 @default.
• W2807324669 hasConceptScore W2807324669C126838900 @default.
• W2807324669 hasConceptScore W2807324669C143998085 @default.
• W2807324669 hasConceptScore W2807324669C146357865 @default.
• W2807324669 hasConceptScore W2807324669C151730666 @default.
• W2807324669 hasConceptScore W2807324669C154945302 @default.
• W2807324669 hasConceptScore W2807324669C2776808855 @default.
• W2807324669 hasConceptScore W2807324669C2779013556 @default.
• W2807324669 hasConceptScore W2807324669C2780325254 @default.
• W2807324669 hasConceptScore W2807324669C2993415550 @default.
• W2807324669 hasConceptScore W2807324669C41008148 @default.
• W2807324669 hasConceptScore W2807324669C71924100 @default.
• W2807324669 hasConceptScore W2807324669C86803240 @default.
• W2807324669 hasConceptScore W2807324669C95623464 @default.
• W2807324669 hasFunder F4320335295 @default.
• W2807324669 hasIssue "2" @default.
• W2807324669 hasLocation W28073246691 @default.
• W2807324669 hasLocation W28073246692 @default.
• W2807324669 hasLocation W28073246693 @default.
• W2807324669 hasLocation W28073246694 @default.
• W2807324669 hasLocation W28073246695 @default.
• W2807324669 hasOpenAccess W2807324669 @default.
• W2807324669 hasPrimaryLocation W28073246691 @default.
• W2807324669 hasRelatedWork W1986775276 @default.
• W2807324669 hasRelatedWork W2344548402 @default.
• W2807324669 hasRelatedWork W2366264134 @default.
• W2807324669 hasRelatedWork W2370641783 @default.
• W2807324669 hasRelatedWork W2901331736 @default.

• next