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• W2807363007 endingPage "21" @default.
• W2807363007 startingPage "10" @default.
• W2807363007 abstract "Many phloem-feeding insects are considered severe pests of agriculture and are controlled mainly by chemical insecticides. Continued extensive use of these inputs is environmentally undesirable, and also leads to the development of insecticide resistance. Here, we used a plant-mediated RNA interference (RNAi) approach, to develop a new control strategy for phloem-feeding insects. The approach aims to silence “key” detoxification genes, involved in the insect's ability to neutralize defensive and toxic plant chemistry. We targeted a glutathione S-transferase (GST) gene, BtGSTs5, in the phloem-feeding whitefly Bemisia tabaci, a devastating global agricultural pest. We report three major findings. First, significant down regulation of the BtGSTs5 gene was obtained in the gut of B. tabaci when the insects were fed on Arabidopsis thaliana transgenic plants expressing dsRNA against BtGSTs5 under a phloem-specific promoter. This brings evidence that phloem-feeding insects can be efficiently targeted by plant-mediated RNAi. Second, in-silico and in-vitro analyses indicated that the BtGSTs5 enzyme can accept as substrates, hydrolyzed aliphatic- and indolic-glucosinolates, and produce their corresponding detoxified conjugates. Third, performance assays suggested that the BtGSTs5 gene silencing prolongs the developmental period of B. tabaci nymphs. Taken together, these findings suggest that BtGSTs5 is likely to play an important role in enabling B. tabaci to successfully feed on glucosinolate-producing plants. Targeting the gene by RNAi in Brassicaceae cropping systems, will likely not eliminate the pest populations from the fields but will significantly reduce their success over the growing season, support prominent activity of natural enemies, eventually allowing the establishment of stable and sustainable agroecosystem." @default.
• W2807363007 created "2018-06-13" @default.
• W2807363007 creator A5028572704 @default.
• W2807363007 creator A5039357557 @default.
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• W2807363007 creator A5067393173 @default.
• W2807363007 creator A5067908464 @default.
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• W2807363007 creator A5087841685 @default.
• W2807363007 creator A5088757844 @default.
• W2807363007 date "2018-09-01" @default.
• W2807363007 modified "2023-10-15" @default.
• W2807363007 title "Targeting detoxification genes by phloem-mediated RNAi: A new approach for controlling phloem-feeding insect pests" @default.
• W2807363007 cites W1528266879 @default.
• W2807363007 cites W1566312669 @default.
• W2807363007 cites W1607931568 @default.
• W2807363007 cites W1742986385 @default.
• W2807363007 cites W1801347402 @default.
• W2807363007 cites W1930167759 @default.
• W2807363007 cites W1966457193 @default.
• W2807363007 cites W1968544137 @default.
• W2807363007 cites W1982294037 @default.
• W2807363007 cites W1984398798 @default.
• W2807363007 cites W1992192767 @default.
• W2807363007 cites W1992909979 @default.
• W2807363007 cites W1996181241 @default.
• W2807363007 cites W1996584217 @default.
• W2807363007 cites W1999613945 @default.
• W2807363007 cites W2004115774 @default.
• W2807363007 cites W2007723833 @default.
• W2807363007 cites W2010404725 @default.
• W2807363007 cites W2010772408 @default.
• W2807363007 cites W2011032714 @default.
• W2807363007 cites W2015765321 @default.
• W2807363007 cites W2017195809 @default.
• W2807363007 cites W2019691413 @default.
• W2807363007 cites W2029436323 @default.
• W2807363007 cites W2034046707 @default.
• W2807363007 cites W2037616695 @default.
• W2807363007 cites W2041285318 @default.
• W2807363007 cites W2044075506 @default.
• W2807363007 cites W2046584841 @default.
• W2807363007 cites W2046922328 @default.
• W2807363007 cites W2054361477 @default.
• W2807363007 cites W2054505085 @default.
• W2807363007 cites W2057400761 @default.
• W2807363007 cites W2063783590 @default.
• W2807363007 cites W2065283382 @default.
• W2807363007 cites W2067027306 @default.
• W2807363007 cites W2071342447 @default.
• W2807363007 cites W2077247797 @default.
• W2807363007 cites W2079089358 @default.
• W2807363007 cites W2079198775 @default.
• W2807363007 cites W2079887141 @default.
• W2807363007 cites W2079902244 @default.
• W2807363007 cites W2086244179 @default.
• W2807363007 cites W2099299146 @default.
• W2807363007 cites W2099307440 @default.
• W2807363007 cites W2099650198 @default.
• W2807363007 cites W2102084974 @default.
• W2807363007 cites W2103353162 @default.
• W2807363007 cites W2105638686 @default.
• W2807363007 cites W2110621280 @default.
• W2807363007 cites W2116110523 @default.
• W2807363007 cites W2116122104 @default.
• W2807363007 cites W2120167126 @default.
• W2807363007 cites W2120366835 @default.
• W2807363007 cites W2121440246 @default.
• W2807363007 cites W2121719758 @default.
• W2807363007 cites W2122033601 @default.
• W2807363007 cites W2126194399 @default.
• W2807363007 cites W2126667640 @default.
• W2807363007 cites W2128328289 @default.
• W2807363007 cites W2130060890 @default.
• W2807363007 cites W2137646763 @default.
• W2807363007 cites W2138136589 @default.
• W2807363007 cites W2142484720 @default.
• W2807363007 cites W2142767735 @default.
• W2807363007 cites W2147021889 @default.
• W2807363007 cites W2147162586 @default.
• W2807363007 cites W2147617258 @default.
• W2807363007 cites W2155721287 @default.
• W2807363007 cites W2156563976 @default.
• W2807363007 cites W2156971141 @default.
• W2807363007 cites W2162402043 @default.
• W2807363007 cites W2163666618 @default.
• W2807363007 cites W2168420558 @default.
• W2807363007 cites W2179197711 @default.
• W2807363007 cites W2276279568 @default.
• W2807363007 cites W2293343887 @default.
• W2807363007 cites W2294999142 @default.
• W2807363007 cites W2310345822 @default.
• W2807363007 cites W2335588833 @default.
• W2807363007 cites W2337339954 @default.
• W2807363007 cites W2408730319 @default.
• W2807363007 cites W2485493954 @default.
• W2807363007 cites W2561455358 @default.

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