Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807427259> ?p ?o ?g. }
- W2807427259 endingPage "515" @default.
- W2807427259 startingPage "506" @default.
- W2807427259 abstract "Purpose: Recently, new studies have brought to light the potential risks of low dose radiation (LDR) in cancer. In this review, we discuss in detail the detrimental effects of LDR in some model organisms and animal models, as well as potential risks to human beings from some routine medical screening procedures. Furthermore, cellular mechanisms by which LDR exerts its negative effects like endoplasmic reticulum stress, epigenetic changes and microRNAs are also reviewed. A few studies are discussed that have reported some benefits of LDR through changes in energy metabolism. Lastly, we focus on breast cancer, one of the predominant forms of cancer potentially affected by LDR and some of the benefits of n-3 polyunsaturated fatty acids (PUFA) as dietary compounds that offer protection against radiation effects on cancer cells and cancer progression.Conclusions: Overall, LDR exerts mainly damaging effects through diverse cell and molecular mechanisms, with a few beneficial effects reported. In some cancers, surrounding adipose tissue of the breast may contribute to obesity-related cancer. Further, preclinical data suggest that anti-inflammatory dietary compounds such as PUFA and other dietary interventions may protect against radiation effects on cancer cells and cancer progression." @default.
- W2807427259 created "2018-06-13" @default.
- W2807427259 creator A5069304662 @default.
- W2807427259 creator A5079819821 @default.
- W2807427259 creator A5084238894 @default.
- W2807427259 creator A5085272051 @default.
- W2807427259 date "2018-07-02" @default.
- W2807427259 modified "2023-10-18" @default.
- W2807427259 title "Low dose radiation, inflammation, cancer and chemoprevention" @default.
- W2807427259 cites W108551223 @default.
- W2807427259 cites W1507728385 @default.
- W2807427259 cites W1511220366 @default.
- W2807427259 cites W1582272383 @default.
- W2807427259 cites W1593058970 @default.
- W2807427259 cites W1903958070 @default.
- W2807427259 cites W1915412071 @default.
- W2807427259 cites W1967476530 @default.
- W2807427259 cites W1968528693 @default.
- W2807427259 cites W1970922227 @default.
- W2807427259 cites W1976423026 @default.
- W2807427259 cites W1976559244 @default.
- W2807427259 cites W1978573204 @default.
- W2807427259 cites W1978627461 @default.
- W2807427259 cites W1978725393 @default.
- W2807427259 cites W1984266465 @default.
- W2807427259 cites W1988567392 @default.
- W2807427259 cites W1991015502 @default.
- W2807427259 cites W1992830797 @default.
- W2807427259 cites W1994545291 @default.
- W2807427259 cites W1998473914 @default.
- W2807427259 cites W2000531576 @default.
- W2807427259 cites W2010429822 @default.
- W2807427259 cites W2011006143 @default.
- W2807427259 cites W2017229007 @default.
- W2807427259 cites W2018339172 @default.
- W2807427259 cites W2024413619 @default.
- W2807427259 cites W2031575431 @default.
- W2807427259 cites W2039491075 @default.
- W2807427259 cites W2040922214 @default.
- W2807427259 cites W2052389197 @default.
- W2807427259 cites W2067141667 @default.
- W2807427259 cites W2069726332 @default.
- W2807427259 cites W2074377041 @default.
- W2807427259 cites W2080578502 @default.
- W2807427259 cites W2081403346 @default.
- W2807427259 cites W2082240623 @default.
- W2807427259 cites W2084287954 @default.
- W2807427259 cites W2084948495 @default.
- W2807427259 cites W2088349637 @default.
- W2807427259 cites W2090190697 @default.
- W2807427259 cites W2093029430 @default.
- W2807427259 cites W2095670074 @default.
- W2807427259 cites W2099571790 @default.
- W2807427259 cites W2108972234 @default.
- W2807427259 cites W2112979733 @default.
- W2807427259 cites W2114438610 @default.
- W2807427259 cites W2122546849 @default.
- W2807427259 cites W2123518190 @default.
- W2807427259 cites W2126481311 @default.
- W2807427259 cites W2126910534 @default.
- W2807427259 cites W2131620064 @default.
- W2807427259 cites W2137571255 @default.
- W2807427259 cites W2140884926 @default.
- W2807427259 cites W2144209063 @default.
- W2807427259 cites W2145405185 @default.
- W2807427259 cites W2145954753 @default.
- W2807427259 cites W2158293301 @default.
- W2807427259 cites W2159728215 @default.
- W2807427259 cites W2163443201 @default.
- W2807427259 cites W2165064047 @default.
- W2807427259 cites W2168288630 @default.
- W2807427259 cites W2170260757 @default.
- W2807427259 cites W2173169563 @default.
- W2807427259 cites W2177315034 @default.
- W2807427259 cites W2235523093 @default.
- W2807427259 cites W2413135499 @default.
- W2807427259 cites W2766698582 @default.
- W2807427259 cites W2781525129 @default.
- W2807427259 cites W312782539 @default.
- W2807427259 doi "https://doi.org/10.1080/09553002.2018.1484194" @default.
- W2807427259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29883256" @default.
- W2807427259 hasPublicationYear "2018" @default.
- W2807427259 type Work @default.
- W2807427259 sameAs 2807427259 @default.
- W2807427259 citedByCount "15" @default.
- W2807427259 countsByYear W28074272592019 @default.
- W2807427259 countsByYear W28074272592020 @default.
- W2807427259 countsByYear W28074272592021 @default.
- W2807427259 countsByYear W28074272592022 @default.
- W2807427259 crossrefType "journal-article" @default.
- W2807427259 hasAuthorship W2807427259A5069304662 @default.
- W2807427259 hasAuthorship W2807427259A5079819821 @default.
- W2807427259 hasAuthorship W2807427259A5084238894 @default.
- W2807427259 hasAuthorship W2807427259A5085272051 @default.
- W2807427259 hasBestOaLocation W28074272591 @default.
- W2807427259 hasConcept C104317684 @default.
- W2807427259 hasConcept C121608353 @default.
- W2807427259 hasConcept C126322002 @default.