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- W2807490372 abstract "Aims & Objectives: To investigate the effect of high-energy formula (HF) on weight gain and gastrointestinal tolerance in postoperative infants with congenital heart disease. Methods A double-blinded randomized controlled trial at a cardiac intensive care unit in a Chinese children’s hospital. Participants were infants <1 year of age after cardiac surgery and were randomly assigned to intervention group (n=32) or control group (n=32). The intervention group received HF (100 kcal/100 mL) and the control group standard formula (67 kcal/100 mL) for 7 postoperative days. Primary outcomes were weight gain and gastrointestinal intolerance; secondary outcomes were prealbumin, energy intake and standard intensive care characteristics. Final analysis included 30 infants in intervention and 29 infants in control group. Trial registration at ClinicalTrials.gov is #NCT02389491. Results Infants who received HF (n=30) showed greater weight gain than those in the control group (n=29) (-0.09 ± 0.18kg/7days versus -0.30 ± 0.22kg/7days, p<0.0001). Gastrointestinal intolerance was observed in the intervention group with abdominal tympany (n=1), gastric retention (n=2), and diarrhea (n=1), while the control group had no problems. The prealnumin showed significant differences at day 7 (p=0.037). Enteral energy intake in the intervention group showed higher than control group from day 3(Figure 1). We observed no significant differences in secondary outcomes of ICU characteristics (Table 1).Conclusions Postoperative infants with congenital heart disease receiving HF gained more weight and experienced some gastrointestinal problems than those infants receiving standard formula. We suggest infants receiving HF were safe and effective, also need more studies to confirm it." @default.
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- W2807490372 date "2018-06-01" @default.
- W2807490372 modified "2023-10-05" @default.
- W2807490372 title "Abstract O-30" @default.
- W2807490372 doi "https://doi.org/10.1097/01.pcc.0000537372.02635.5e" @default.
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