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• W2807646536 abstract "Advances in Pancreatic Cancer Treatment Surgical therapy for pancreatic cancerNorbert Hüser, Volker Aßfalg & Helmut FriessNorbert HüserNorbert Hüser is a consultant surgeon with special clinical interest and scientific emphasis in hepato–pancreato–biliary surgery, transplantation and microsurgery. He has many years of surgical experience and scientific work in the Munich Hepato–Pancreato–Biliary Group of the Pancreatic Center at the Klinikum rechts der Isar der Technischen Universität München, Munich, Germany, evidence his experience in this field.Search for more papers by this author, Volker AßfalgVolker Aßfalg is a consultant surgeon at the Deptartment of Surgery, Klinikum rechts der Isar der Technischen Universität München. He has long-term experience in general and visceral surgery, solid organ transplantation, microsurgery, intensive care medicine, and interdisciplinary tumor treatment. His present clinical focus in the department is perioperative disease management and optimized multimodal palliative tumor treatment.Search for more papers by this author & Helmut FriessHelmut Friess is Professor of Surgery and Chairman of the Department of Surgery at the Technische Universität München. From 2001 to 2007 he held the post of Vice Chairman of the Department of General Surgery at the University of Heidelberg, Germany, and from 2003 to 2007 he was also Professor of Pancreatic Surgery and Molecular Pancreatic Research at this institution. He has authored more than 800 original peer-reviewed publications, is Co-Editor of Langenbeck’s Archives of Surgery since 2007, Assistant Editor of the Journal of Digestive Surgery and serves on the editorial boards of the Journal of the Pancreas, Molecular Cancer, British Journal of Surgery and Pancreatology. He is council member at large for the International Hepato-Pancreato-Biliary Association (IHPBA) and a member of the General Assembly, United European Gastroenterology Federation (UEGF) since 2003. He is Secretary of European Digestive Surgery (EDS) and the European Pancreatic Club (EPC).Search for more papers by this authorPublished Online:16 Dec 2011https://doi.org/10.2217/ebo.11.189AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInReddit View chapterAbstract: Complete resection of pancreatic carcinoma is the only possibility of curative therapy. Hence, the fundamental aim of all investigatory procedures for preoperative staging and individualized therapy planning is the differentiation of those patients with either resectable, doubtful resectable or unresectable tumors (Figure 3.1). Surgical treatment of these patients obtained considerable advances during the last few years and perioperative morbidity and as a consequence mortality decreased in the so-called high-volume centers. Despite these achievements in early results, approximately 80% of patients show unresectable tumor stage at the time of making the diagnosis. Furthermore and consistingly with the small number of long-term survivors, early local tumor recurrence and/or predominantly hepatic metastatic spread due to lymphatic and perineural tumor cell dissemination must be mentioned. In this situation, surgical therapy has its status in palliation and facilitation of best possible life quality – always dependent on morbidity and patient’s general health condition. References1 van Heek NT , Kuhlmann KF , Scholten RJ et al. Hospital volume and mortality after pancreatic resection: a systematic review and an evaluation of intervention in the Netherlands . Ann. Surg. 242 (6) , 788 – 790 (2005) . 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