Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807647098> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2807647098 endingPage "3549" @default.
- W2807647098 startingPage "3543" @default.
- W2807647098 abstract "Background/Aim: Definitive chemoradiation (CRT) is a common approach for locally advanced hypopharyngeal squamous cell carcinoma (SCC) with the goal of organ preservation. Reports on long-term oncologic and functional outcomes have been limited. This study reports on outcomes utilizing this approach at a single institution over 30 years. Materials and Methods: Medical records for patients with stage III-IVB SCC of the hypopharynx were retrospectively reviewed. Patient and disease-related factors were identified and analyzed for impact on overall survival (OS), cancer-specific survival (CSS), disease-free survival, distant failure, and locoregional failure. Results: A total of 54 patients were identified who were treated with definitive CRT to a mean dose of 72 Gy. With a median follow-up period of 49.8 months, 5- and 10-year OS was 62% and 43% respectively. Five and 10-year CSS were 74% and 72% respectively. Ten-year local control was 78%. Of the 37 patients with no treatment failure, 29% experienced a grade 3 or higher late toxicity, with the majority resolving during continued long-term follow-up. Conclusion: This study demonstrates good outcomes with long-term follow-up with acceptable rates of late toxicities. The findings here represent the longest published median follow-up in this population and validate the strategy of organ preservation." @default.
- W2807647098 created "2018-06-13" @default.
- W2807647098 creator A5011221111 @default.
- W2807647098 creator A5017367541 @default.
- W2807647098 creator A5031788305 @default.
- W2807647098 creator A5038528892 @default.
- W2807647098 creator A5045294159 @default.
- W2807647098 creator A5056207842 @default.
- W2807647098 creator A5064088665 @default.
- W2807647098 creator A5074667746 @default.
- W2807647098 creator A5079876890 @default.
- W2807647098 creator A5088815126 @default.
- W2807647098 creator A5089337136 @default.
- W2807647098 creator A5089460717 @default.
- W2807647098 date "2018-05-30" @default.
- W2807647098 modified "2023-10-14" @default.
- W2807647098 title "Definitive Chemoradiation in Locally Advanced Squamous Cell Carcinoma of the Hypopharynx: Long-term Outcomes and Toxicity" @default.
- W2807647098 doi "https://doi.org/10.21873/anticanres.12626" @default.
- W2807647098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29848708" @default.
- W2807647098 hasPublicationYear "2018" @default.
- W2807647098 type Work @default.
- W2807647098 sameAs 2807647098 @default.
- W2807647098 citedByCount "14" @default.
- W2807647098 countsByYear W28076470982019 @default.
- W2807647098 countsByYear W28076470982020 @default.
- W2807647098 countsByYear W28076470982022 @default.
- W2807647098 countsByYear W28076470982023 @default.
- W2807647098 crossrefType "journal-article" @default.
- W2807647098 hasAuthorship W2807647098A5011221111 @default.
- W2807647098 hasAuthorship W2807647098A5017367541 @default.
- W2807647098 hasAuthorship W2807647098A5031788305 @default.
- W2807647098 hasAuthorship W2807647098A5038528892 @default.
- W2807647098 hasAuthorship W2807647098A5045294159 @default.
- W2807647098 hasAuthorship W2807647098A5056207842 @default.
- W2807647098 hasAuthorship W2807647098A5064088665 @default.
- W2807647098 hasAuthorship W2807647098A5074667746 @default.
- W2807647098 hasAuthorship W2807647098A5079876890 @default.
- W2807647098 hasAuthorship W2807647098A5088815126 @default.
- W2807647098 hasAuthorship W2807647098A5089337136 @default.
- W2807647098 hasAuthorship W2807647098A5089460717 @default.
- W2807647098 hasBestOaLocation W28076470981 @default.
- W2807647098 hasConcept C121608353 @default.
- W2807647098 hasConcept C126322002 @default.
- W2807647098 hasConcept C141071460 @default.
- W2807647098 hasConcept C143998085 @default.
- W2807647098 hasConcept C146357865 @default.
- W2807647098 hasConcept C151730666 @default.
- W2807647098 hasConcept C167135981 @default.
- W2807647098 hasConcept C195910791 @default.
- W2807647098 hasConcept C2777546739 @default.
- W2807647098 hasConcept C2778424827 @default.
- W2807647098 hasConcept C2908647359 @default.
- W2807647098 hasConcept C29730261 @default.
- W2807647098 hasConcept C3019992690 @default.
- W2807647098 hasConcept C509974204 @default.
- W2807647098 hasConcept C71924100 @default.
- W2807647098 hasConcept C86803240 @default.
- W2807647098 hasConcept C99454951 @default.
- W2807647098 hasConceptScore W2807647098C121608353 @default.
- W2807647098 hasConceptScore W2807647098C126322002 @default.
- W2807647098 hasConceptScore W2807647098C141071460 @default.
- W2807647098 hasConceptScore W2807647098C143998085 @default.
- W2807647098 hasConceptScore W2807647098C146357865 @default.
- W2807647098 hasConceptScore W2807647098C151730666 @default.
- W2807647098 hasConceptScore W2807647098C167135981 @default.
- W2807647098 hasConceptScore W2807647098C195910791 @default.
- W2807647098 hasConceptScore W2807647098C2777546739 @default.
- W2807647098 hasConceptScore W2807647098C2778424827 @default.
- W2807647098 hasConceptScore W2807647098C2908647359 @default.
- W2807647098 hasConceptScore W2807647098C29730261 @default.
- W2807647098 hasConceptScore W2807647098C3019992690 @default.
- W2807647098 hasConceptScore W2807647098C509974204 @default.
- W2807647098 hasConceptScore W2807647098C71924100 @default.
- W2807647098 hasConceptScore W2807647098C86803240 @default.
- W2807647098 hasConceptScore W2807647098C99454951 @default.
- W2807647098 hasIssue "6" @default.
- W2807647098 hasLocation W28076470981 @default.
- W2807647098 hasLocation W28076470982 @default.
- W2807647098 hasOpenAccess W2807647098 @default.
- W2807647098 hasPrimaryLocation W28076470981 @default.
- W2807647098 hasRelatedWork W2003938723 @default.
- W2807647098 hasRelatedWork W2047967234 @default.
- W2807647098 hasRelatedWork W2110125130 @default.
- W2807647098 hasRelatedWork W2155941014 @default.
- W2807647098 hasRelatedWork W2366542491 @default.
- W2807647098 hasRelatedWork W2404042595 @default.
- W2807647098 hasRelatedWork W2439875401 @default.
- W2807647098 hasRelatedWork W4220939315 @default.
- W2807647098 hasRelatedWork W4245694863 @default.
- W2807647098 hasRelatedWork W4307122576 @default.
- W2807647098 hasVolume "38" @default.
- W2807647098 isParatext "false" @default.
- W2807647098 isRetracted "false" @default.
- W2807647098 magId "2807647098" @default.
- W2807647098 workType "article" @default.