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- W2807676807 endingPage "659" @default.
- W2807676807 startingPage "651" @default.
- W2807676807 abstract "It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenesis. Different signaling pathways play a part in the carcinogenesis that occurs in a cell. Among these pathways, the Wnt signaling pathway plays a predominant role in carcinogenesis and is known as a central cellular pathway in the development of tumors. There are three Wnt signaling pathways that are well identified, including the canonical or Wnt/β-catenin dependent pathway, the noncanonical or β-catenin-independent planar cell polarity (PCP) pathway, and the noncanonical Wnt/Ca2+ pathway. Most of the oncogenic viruses modulate the canonical Wnt signaling pathway. This review discusses the interaction between proteins of several human oncogenic viruses with the Wnt signaling pathway." @default.
- W2807676807 created "2018-06-13" @default.
- W2807676807 creator A5020922298 @default.
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- W2807676807 creator A5064621754 @default.
- W2807676807 creator A5077373272 @default.
- W2807676807 creator A5086753264 @default.
- W2807676807 date "2018-07-01" @default.
- W2807676807 modified "2023-09-29" @default.
- W2807676807 title "Interaction of viral oncogenic proteins with the Wnt signaling pathway." @default.
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