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- W2807691014 abstract "Musculoskeletal injuries impact millions of people globally and affect their health and well-being as well as of their companion and athletic animals. Soft-tissue injuries represent almost half of these and are associated with unorganized scar tissue formation and long time-depending healing processes. Cell-based therapeutic strategies have been developed in the past decades aiming at the treatment and reversion of such disorders. Stem cells are fairly appealing in the field, being a responsive undifferentiated population, with ability to self-renew and differentiate into different lineages. Mesenchymal stem cells (MSCs) can be obtained from several adult tissues, including the synovial membrane. Synovia-derived MSCs can be found in individuals of any age and are associated to intrinsic regenerative processes, through both paracrine and cell-to-cell interactions, thus, contributing to hosts’ healing capacity. Studies have demonstrated the potential benefit of synovia-derived MSCs in these regenerative processes in both human and veterinary medicine. The purpose of this chapter is to review the literature regarding SM-MSC therapies applied to musculoskeletal disorders, in both human and veterinary medicine." @default.
- W2807691014 created "2018-06-13" @default.
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- W2807691014 date "2018-06-06" @default.
- W2807691014 modified "2023-10-01" @default.
- W2807691014 title "Synovia-Derived Mesenchymal Stem Cell Application in Musculoskeletal Injuries: A Review" @default.
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- W2807691014 doi "https://doi.org/10.5772/intechopen.74596" @default.
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