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• W2807703896 startingPage "1" @default.
• W2807703896 abstract "Acinetobacter baumannii is a notorious pathogen that has emerged as a healthcare nightmare in recent years because it causes serious infections that are associated with high morbidity and mortality rates. Due to its exceptional ability to acquire resistance to almost all available antibiotics, A. baumannii is currently ranked as the first pathogen on the World Health Organization’s priority list for the development of new antibiotics. The versatile range of effectors secreted by A. baumannii represents a large proportion of the virulence arsenal identified in this bacterium to date. Thus, these factors, together with the secretory machinery responsible for their extrusion into the extracellular milieu, are key targets for novel therapeutics that are greatly needed to combat this deadly pathogen. In this review, we provide a comprehensive, up-to-date overview of the organization and regulatory aspects of the Acinetobacter secretion systems, with a special emphasis on their versatile substrates that could be targeted to fight the deadly infections caused by this elusive pathogen." @default.
• W2807703896 created "2018-06-13" @default.
• W2807703896 creator A5024284926 @default.
• W2807703896 creator A5045638928 @default.
• W2807703896 date "2018-03-21" @default.
• W2807703896 modified "2023-09-26" @default.
• W2807703896 title "<i>Acinetobacter</i>: an emerging pathogen with a versatile secretome" @default.
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