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- W2807736768 abstract "Introduction: Microneedle (MN) arrays contain a backing plate with multiple microscopic projections to puncture the skin and can be used to deliver drug in a minimally invasive way. Advantages of MNs are numerous including administration of large molecules, avoiding first-pass metabolism, ease of administration, lack of pain, site-specific drug targeting, and dose reduction due to increased absorption efficacy. The growth in the transdermal market has been fueled by an increasing number of chronic disease patients and a demand for easy and pain-free drug administration.Areas covered: This paper highlights the use of MNs as a drug delivery system and discusses their potential market impact from a cost perspective. A number of clinical trials have been conducted and are listed to illustrate the potential applications of MNs for therapeutic use. Furthermore, the cosmetic market has made use of the MN technology, indicating that MNs can be used safely, efficaciously, and on a commercial scale. Furthermore, the cost-effectiveness of MNs is discussed.Expert commentary: For MNs to become commercially available for therapeutic use, a number of factors will need to be considered: safety, ease of use, manufacturing and storage, uptake, effectiveness, and regulatory requirements." @default.
- W2807736768 created "2018-06-21" @default.
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- W2807736768 date "2018-06-14" @default.
- W2807736768 modified "2023-09-22" @default.
- W2807736768 title "Therapeutic applications and pharmacoeconomics of microneedle technology" @default.
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- W2807736768 doi "https://doi.org/10.1080/14737167.2018.1485100" @default.
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