Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807746132> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2807746132 endingPage "R694" @default.
- W2807746132 startingPage "R693" @default.
- W2807746132 abstract "Present-day giant pandas (Ailuropoda melanoleuca) are estimated to have diverged from their closest relatives, all other bears, ∼20 million years ago, based on molecular data [1Hu Y. Wu Q. Ma S. Ma T. Shan L. Wang X. Nie Y. Ning Z. Yan L. Xiu Y. et al.Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas.Proc. Natl. Acad. Sci. USA. 2017; 114: 1081-1086Crossref PubMed Scopus (135) Google Scholar]. With fewer than 2,500 individuals living today [2Wei F. Hu Y. Zhu L. Bruford M.W. Zhan X. Zhang L. Black and white and read all over: The past, present and future of giant panda genetics.Mol. Ecol. 2012; 21: 5660-5674Crossref PubMed Scopus (77) Google Scholar], it is unclear how well genetic data from extant and historical giant pandas [3Zhu L. Hu Y. Qi D. Wu H. Zhan X. Zhang Z. Bruford M.W. Wang J. Yang X. Gu X. et al.Genetic consequences of historical anthropogenic and ecological events on giant pandas.Ecology. 2013; 94: 2346-2357Crossref PubMed Scopus (31) Google Scholar] reflect the past [3Zhu L. Hu Y. Qi D. Wu H. Zhan X. Zhang Z. Bruford M.W. Wang J. Yang X. Gu X. et al.Genetic consequences of historical anthropogenic and ecological events on giant pandas.Ecology. 2013; 94: 2346-2357Crossref PubMed Scopus (31) Google Scholar]. To date, there has been no complete mitochondrial DNA (mtDNA) sequenced from an ancient giant panda. Here, we use ancient DNA capture techniques [4Fu Q. Meyer M. Gao X. Stenzel U. Burbano H.A. Kelso J. Paabo S. DNA analysis of an early modern human from Tianyuan Cave, China.Proc. Natl. Acad. Sci. USA. 2013; 110: 2223-2227Crossref PubMed Scopus (333) Google Scholar] to sequence the complete mitochondrial genome of a ∼22,000-year-old giant panda specimen (radiocarbon date of 21,910–21,495 cal BP with ± 2σ at 95.4% probability; Lab.no Beta-473743) from the Cizhutuo Cave, in Leye County, Guangxi Province, China (Figure 1A). Its date and location in Guangxi, where no wild giant pandas live today, as well as the difficulty of DNA preservation in a hot and humid region, place it as a unique specimen to learn about ancient giant pandas from the last glacial maximum. We find that the mtDNA lineage of the Cizhutuo panda coalesced with present-day pandas ∼183 thousand years ago (kya, 95% HPD, 227–144 kya), earlier than the time to the most recent common ancestor (TMRCA) of mtDNA lineages shared by present-day pandas (∼72 kya, 95% HPD, 94–55 kya, Supplemental Information). Furthermore, the Cizhutuo panda possessed 18 non-synonymous mutations across six mitochondrial genes. Our results show that the Cizhutuo mtDNA lineage underwent a distinct history from that of present-day populations." @default.
- W2807746132 created "2018-06-21" @default.
- W2807746132 creator A5014205432 @default.
- W2807746132 creator A5020972239 @default.
- W2807746132 creator A5028804808 @default.
- W2807746132 creator A5036993680 @default.
- W2807746132 creator A5041045003 @default.
- W2807746132 creator A5069720395 @default.
- W2807746132 creator A5074473139 @default.
- W2807746132 creator A5081061698 @default.
- W2807746132 creator A5083460724 @default.
- W2807746132 date "2018-06-01" @default.
- W2807746132 modified "2023-09-25" @default.
- W2807746132 title "Mitochondrial genome of a 22,000-year-old giant panda from southern China reveals a new panda lineage" @default.
- W2807746132 cites W1977808529 @default.
- W2807746132 cites W2022327489 @default.
- W2807746132 cites W2126874964 @default.
- W2807746132 cites W2149683346 @default.
- W2807746132 cites W2153566382 @default.
- W2807746132 cites W2165767452 @default.
- W2807746132 cites W2577093329 @default.
- W2807746132 cites W2606052718 @default.
- W2807746132 doi "https://doi.org/10.1016/j.cub.2018.05.008" @default.
- W2807746132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29920259" @default.
- W2807746132 hasPublicationYear "2018" @default.
- W2807746132 type Work @default.
- W2807746132 sameAs 2807746132 @default.
- W2807746132 citedByCount "17" @default.
- W2807746132 countsByYear W28077461322018 @default.
- W2807746132 countsByYear W28077461322019 @default.
- W2807746132 countsByYear W28077461322020 @default.
- W2807746132 countsByYear W28077461322021 @default.
- W2807746132 countsByYear W28077461322022 @default.
- W2807746132 countsByYear W28077461322023 @default.
- W2807746132 crossrefType "journal-article" @default.
- W2807746132 hasAuthorship W2807746132A5014205432 @default.
- W2807746132 hasAuthorship W2807746132A5020972239 @default.
- W2807746132 hasAuthorship W2807746132A5028804808 @default.
- W2807746132 hasAuthorship W2807746132A5036993680 @default.
- W2807746132 hasAuthorship W2807746132A5041045003 @default.
- W2807746132 hasAuthorship W2807746132A5069720395 @default.
- W2807746132 hasAuthorship W2807746132A5074473139 @default.
- W2807746132 hasAuthorship W2807746132A5081061698 @default.
- W2807746132 hasAuthorship W2807746132A5083460724 @default.
- W2807746132 hasBestOaLocation W28077461321 @default.
- W2807746132 hasConcept C104317684 @default.
- W2807746132 hasConcept C138885662 @default.
- W2807746132 hasConcept C15708023 @default.
- W2807746132 hasConcept C18903297 @default.
- W2807746132 hasConcept C193252679 @default.
- W2807746132 hasConcept C203014093 @default.
- W2807746132 hasConcept C24586158 @default.
- W2807746132 hasConcept C2776338565 @default.
- W2807746132 hasConcept C2908694543 @default.
- W2807746132 hasConcept C54355233 @default.
- W2807746132 hasConcept C78458016 @default.
- W2807746132 hasConcept C86803240 @default.
- W2807746132 hasConcept C90856448 @default.
- W2807746132 hasConceptScore W2807746132C104317684 @default.
- W2807746132 hasConceptScore W2807746132C138885662 @default.
- W2807746132 hasConceptScore W2807746132C15708023 @default.
- W2807746132 hasConceptScore W2807746132C18903297 @default.
- W2807746132 hasConceptScore W2807746132C193252679 @default.
- W2807746132 hasConceptScore W2807746132C203014093 @default.
- W2807746132 hasConceptScore W2807746132C24586158 @default.
- W2807746132 hasConceptScore W2807746132C2776338565 @default.
- W2807746132 hasConceptScore W2807746132C2908694543 @default.
- W2807746132 hasConceptScore W2807746132C54355233 @default.
- W2807746132 hasConceptScore W2807746132C78458016 @default.
- W2807746132 hasConceptScore W2807746132C86803240 @default.
- W2807746132 hasConceptScore W2807746132C90856448 @default.
- W2807746132 hasIssue "12" @default.
- W2807746132 hasLocation W28077461321 @default.
- W2807746132 hasLocation W28077461322 @default.
- W2807746132 hasOpenAccess W2807746132 @default.
- W2807746132 hasPrimaryLocation W28077461321 @default.
- W2807746132 hasRelatedWork W1541222846 @default.
- W2807746132 hasRelatedWork W1967807546 @default.
- W2807746132 hasRelatedWork W1979674832 @default.
- W2807746132 hasRelatedWork W2006556423 @default.
- W2807746132 hasRelatedWork W2108480306 @default.
- W2807746132 hasRelatedWork W2114346040 @default.
- W2807746132 hasRelatedWork W2364875879 @default.
- W2807746132 hasRelatedWork W2417800113 @default.
- W2807746132 hasRelatedWork W2948012419 @default.
- W2807746132 hasRelatedWork W44090667 @default.
- W2807746132 hasVolume "28" @default.
- W2807746132 isParatext "false" @default.
- W2807746132 isRetracted "false" @default.
- W2807746132 magId "2807746132" @default.
- W2807746132 workType "article" @default.