Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807761246> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2807761246 endingPage "111" @default.
- W2807761246 startingPage "107" @default.
- W2807761246 abstract "Muscle damage resulting from eccentric exercise provides a useful model of oxyradical-induced injury and can be used to examine age-related responses to oxidative stress. Sixteen young (26.4 ± 3.3 years) and 16 older (71.1 ± 4.0 years) healthy men were randomly assigned to 1000 IU/d vitamin E or placebo for 12 weeks and ran downhill for 45 min at 75% VO2max, once before and following supplementation. Blood samples were obtained before (baseline) and immediately postexercise (0 h), and at 6, 24, and 72 h postexercise to determine antioxidant status, muscle damage, lipid peroxidation, and DNA damage. Following exercise, young and older men experienced similar increases in serum creatine kinase (CK), F2α-isoprostanes (iPF2α; p < .001) and malondialdehyde (MDA; p < .01), although iPF2α peaked at 72 h postexercise and MDA peaked at 0 h. Oxygen Radical Absorbance Capacity (ORAC) decreased at 72 h (p < .01) and correlated with the rise in iPF2α, MDA, and CK in the young men (p < .05). Leukocyte 8-hydroxy-2′-deoxyguanosine (8-OHdG) was unaffected by exercise. Vitamin E decreased peak CK in young men, while in older men it decreased resting levels of iPF2α and suppressed the 24 h postexercise increases in iPF2α (p < .05). Thus, vitamin E supplementation induced modest changes eccentric exercise-induced oxidative stress, although differentially between the young and older subjects, while age had no direct influence on these responses among this group of physically fit subjects." @default.
- W2807761246 created "2018-06-21" @default.
- W2807761246 date "2004-01-01" @default.
- W2807761246 modified "2023-09-25" @default.
- W2807761246 title "P11. Oxidative and Nitrosative Stress in Metabolic Disorders" @default.
- W2807761246 doi "https://doi.org/10.1016/j.freeradbiomed.2004.02.029" @default.
- W2807761246 hasPublicationYear "2004" @default.
- W2807761246 type Work @default.
- W2807761246 sameAs 2807761246 @default.
- W2807761246 citedByCount "0" @default.
- W2807761246 crossrefType "journal-article" @default.
- W2807761246 hasConcept C126322002 @default.
- W2807761246 hasConcept C134018914 @default.
- W2807761246 hasConcept C185592680 @default.
- W2807761246 hasConcept C2776151105 @default.
- W2807761246 hasConcept C2776188313 @default.
- W2807761246 hasConcept C2777551382 @default.
- W2807761246 hasConcept C2778004101 @default.
- W2807761246 hasConcept C2778401633 @default.
- W2807761246 hasConcept C2780829032 @default.
- W2807761246 hasConcept C2993539680 @default.
- W2807761246 hasConcept C36880943 @default.
- W2807761246 hasConcept C55493867 @default.
- W2807761246 hasConcept C71924100 @default.
- W2807761246 hasConceptScore W2807761246C126322002 @default.
- W2807761246 hasConceptScore W2807761246C134018914 @default.
- W2807761246 hasConceptScore W2807761246C185592680 @default.
- W2807761246 hasConceptScore W2807761246C2776151105 @default.
- W2807761246 hasConceptScore W2807761246C2776188313 @default.
- W2807761246 hasConceptScore W2807761246C2777551382 @default.
- W2807761246 hasConceptScore W2807761246C2778004101 @default.
- W2807761246 hasConceptScore W2807761246C2778401633 @default.
- W2807761246 hasConceptScore W2807761246C2780829032 @default.
- W2807761246 hasConceptScore W2807761246C2993539680 @default.
- W2807761246 hasConceptScore W2807761246C36880943 @default.
- W2807761246 hasConceptScore W2807761246C55493867 @default.
- W2807761246 hasConceptScore W2807761246C71924100 @default.
- W2807761246 hasLocation W28077612461 @default.
- W2807761246 hasOpenAccess W2807761246 @default.
- W2807761246 hasPrimaryLocation W28077612461 @default.
- W2807761246 hasRelatedWork W1989464476 @default.
- W2807761246 hasRelatedWork W2003518555 @default.
- W2807761246 hasRelatedWork W2069460849 @default.
- W2807761246 hasRelatedWork W2143948660 @default.
- W2807761246 hasRelatedWork W2169892970 @default.
- W2807761246 hasRelatedWork W2232758008 @default.
- W2807761246 hasRelatedWork W2432277451 @default.
- W2807761246 hasRelatedWork W2434937718 @default.
- W2807761246 hasRelatedWork W2904352247 @default.
- W2807761246 hasRelatedWork W4301699110 @default.
- W2807761246 hasVolume "36" @default.
- W2807761246 isParatext "false" @default.
- W2807761246 isRetracted "false" @default.
- W2807761246 magId "2807761246" @default.
- W2807761246 workType "article" @default.