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- W2807834367 abstract "A novel series of N,N'-bis[2-oxo-2H-1-benzopyran]-3-carboxamide derivatives have been synthesized and investigated for the ability to inhibit the activity of the A and B isoforms of monoamine oxidase (MAO). Some of the synthesized compounds show good selective inhibitory activity against the MAO-A isoform. Both the MAO-A and -B isoforms, deposited in the Protein Data Bank as the 2BXR and 1GOS models, respectively, were considered in a computational study performed with docking techniques on the most active and selective inhibitors." @default.
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- W2807834367 date "2006-08-01" @default.
- W2807834367 modified "2023-10-13" @default.
- W2807834367 title "Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of N,N′-bis[2-oxo-2H-benzopyran]-3-carboxamides" @default.
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- W2807834367 doi "https://doi.org/10.1016/j.bmcl.2006.04.026" @default.
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