Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807952010> ?p ?o ?g. }
- W2807952010 abstract "We aimed to evaluate the efficacy and tolerability of citicoline add-on therapy in treatment of negative symptoms in patients with stable schizophrenia.In a double-blind and placebo-controlled study, patients with stable schizophrenia (DSM-5) were randomized to receive either 2,500 mg/day citicoline or placebo in addition to risperidone for 8 weeks. The patients were assessed using the positive and negative syndrome scale (PANSS), the extrapyramidal symptom rating scale (ESRS), and Hamilton depression rating scale (HDRS). The primary outcome was the difference in PANSS negative subscale score reduction from baseline to week 8 between the citicoline and the placebo groups.Sixty-six individuals (out of 73 enrolled) completed the trial. The citicoline group demonstrated significantly greater improvement in negative scores, F(1.840, 118.360) = 8.383, p = .001, as well as general psychopathology, F(1.219, 78.012) = 6.636, p = .008; change in general psychopathology did not remain significant after adjustment, and total PANSS scores, F(1.633, 104.487) = 15.400, p < .001, compared with the placebo. HDRS scores and its changes, ESRS score, and frequency of other side effects were not significantly different between the two groups.Citicoline add-on therapy to risperidone can effectively improve the primary negative symptoms of patients with schizophrenia." @default.
- W2807952010 created "2018-06-21" @default.
- W2807952010 creator A5007447653 @default.
- W2807952010 creator A5012491250 @default.
- W2807952010 creator A5024641752 @default.
- W2807952010 creator A5056695741 @default.
- W2807952010 creator A5074774874 @default.
- W2807952010 creator A5088810181 @default.
- W2807952010 creator A5069656569 @default.
- W2807952010 date "2018-06-14" @default.
- W2807952010 modified "2023-09-26" @default.
- W2807952010 title "Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: A double-blind, randomized placebo-controlled trial" @default.
- W2807952010 cites W1493378518 @default.
- W2807952010 cites W1965821399 @default.
- W2807952010 cites W1965924432 @default.
- W2807952010 cites W1967209958 @default.
- W2807952010 cites W1977994579 @default.
- W2807952010 cites W1991588393 @default.
- W2807952010 cites W2003510525 @default.
- W2807952010 cites W2005044038 @default.
- W2807952010 cites W2012468010 @default.
- W2807952010 cites W2018099032 @default.
- W2807952010 cites W2018872938 @default.
- W2807952010 cites W2028562300 @default.
- W2807952010 cites W2043219129 @default.
- W2807952010 cites W2064104052 @default.
- W2807952010 cites W2072838806 @default.
- W2807952010 cites W2099058526 @default.
- W2807952010 cites W2099191115 @default.
- W2807952010 cites W2110613853 @default.
- W2807952010 cites W2114613490 @default.
- W2807952010 cites W2120352446 @default.
- W2807952010 cites W2120754512 @default.
- W2807952010 cites W2121720045 @default.
- W2807952010 cites W2124533302 @default.
- W2807952010 cites W2130148029 @default.
- W2807952010 cites W2140606211 @default.
- W2807952010 cites W2149069617 @default.
- W2807952010 cites W2155797616 @default.
- W2807952010 cites W2171111401 @default.
- W2807952010 cites W2176147150 @default.
- W2807952010 cites W2410279573 @default.
- W2807952010 cites W2614230448 @default.
- W2807952010 cites W2762182197 @default.
- W2807952010 cites W2792290331 @default.
- W2807952010 doi "https://doi.org/10.1002/hup.2662" @default.
- W2807952010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29901250" @default.
- W2807952010 hasPublicationYear "2018" @default.
- W2807952010 type Work @default.
- W2807952010 sameAs 2807952010 @default.
- W2807952010 citedByCount "4" @default.
- W2807952010 countsByYear W28079520102020 @default.
- W2807952010 countsByYear W28079520102021 @default.
- W2807952010 countsByYear W28079520102023 @default.
- W2807952010 crossrefType "journal-article" @default.
- W2807952010 hasAuthorship W2807952010A5007447653 @default.
- W2807952010 hasAuthorship W2807952010A5012491250 @default.
- W2807952010 hasAuthorship W2807952010A5024641752 @default.
- W2807952010 hasAuthorship W2807952010A5056695741 @default.
- W2807952010 hasAuthorship W2807952010A5069656569 @default.
- W2807952010 hasAuthorship W2807952010A5074774874 @default.
- W2807952010 hasAuthorship W2807952010A5088810181 @default.
- W2807952010 hasConcept C118552586 @default.
- W2807952010 hasConcept C126322002 @default.
- W2807952010 hasConcept C138496976 @default.
- W2807952010 hasConcept C142724271 @default.
- W2807952010 hasConcept C15744967 @default.
- W2807952010 hasConcept C168563851 @default.
- W2807952010 hasConcept C197934379 @default.
- W2807952010 hasConcept C204787440 @default.
- W2807952010 hasConcept C27081682 @default.
- W2807952010 hasConcept C2776412080 @default.
- W2807952010 hasConcept C2778375690 @default.
- W2807952010 hasConcept C2778689640 @default.
- W2807952010 hasConcept C2779727114 @default.
- W2807952010 hasConcept C2780057945 @default.
- W2807952010 hasConcept C2780135775 @default.
- W2807952010 hasConcept C2780494398 @default.
- W2807952010 hasConcept C2780496003 @default.
- W2807952010 hasConcept C2780616385 @default.
- W2807952010 hasConcept C42219234 @default.
- W2807952010 hasConcept C71924100 @default.
- W2807952010 hasConcept C83849319 @default.
- W2807952010 hasConceptScore W2807952010C118552586 @default.
- W2807952010 hasConceptScore W2807952010C126322002 @default.
- W2807952010 hasConceptScore W2807952010C138496976 @default.
- W2807952010 hasConceptScore W2807952010C142724271 @default.
- W2807952010 hasConceptScore W2807952010C15744967 @default.
- W2807952010 hasConceptScore W2807952010C168563851 @default.
- W2807952010 hasConceptScore W2807952010C197934379 @default.
- W2807952010 hasConceptScore W2807952010C204787440 @default.
- W2807952010 hasConceptScore W2807952010C27081682 @default.
- W2807952010 hasConceptScore W2807952010C2776412080 @default.
- W2807952010 hasConceptScore W2807952010C2778375690 @default.
- W2807952010 hasConceptScore W2807952010C2778689640 @default.
- W2807952010 hasConceptScore W2807952010C2779727114 @default.
- W2807952010 hasConceptScore W2807952010C2780057945 @default.
- W2807952010 hasConceptScore W2807952010C2780135775 @default.
- W2807952010 hasConceptScore W2807952010C2780494398 @default.
- W2807952010 hasConceptScore W2807952010C2780496003 @default.