Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808038721> ?p ?o ?g. }
- W2808038721 abstract "Background: Writer's cramp (WC) is a task-specific focal hand dystonia presenting with pain, stiffness and/or tremor while writing. We explored the involvement of cortical and brainstem circuits by measuring intermuscular coherence (IMC) and pre-pulse inhibition (PPI) of the blink reflex. Methods: IMC was measured in 10 healthy controls and 20 WC patients (10 with associated tremor) while they performed a precision grip task at different force levels. Blink responses were evaluated in 9 healthy controls and 10 WC patients by stimulating the right supraorbital nerve and recording surface EMG from the orbicularis oculi muscles bilaterally. PPI involved conditioning this stimulation with a prior shock to the right median nerve (100 ms interval), and measuring the reduction in the R2 component of the blink reflex. Results: Significant IMC at 3-7 Hz was present in WC patients, but not in healthy controls. Compared to healthy controls, in WC patients the R2 component of the blink reflex showed significantly less PPI. IMC at 3-7 Hz could reliably discriminate WC patients from healthy controls. Conclusion: Cortical or sub-cortical circuits generating theta (3-7 Hz) oscillations might play an important role in the pathogenesis of WC. Moreover, the lack of PPI implicates abnormalities in brainstem inhibition in the emergence of WC. IMC may merit further development as an electrodiagnostic test for focal dystonia." @default.
- W2808038721 created "2018-06-21" @default.
- W2808038721 creator A5006213258 @default.
- W2808038721 creator A5020929906 @default.
- W2808038721 creator A5024202488 @default.
- W2808038721 creator A5035320748 @default.
- W2808038721 creator A5061382191 @default.
- W2808038721 creator A5062329709 @default.
- W2808038721 creator A5078896471 @default.
- W2808038721 creator A5082280984 @default.
- W2808038721 date "2018-07-02" @default.
- W2808038721 modified "2023-10-10" @default.
- W2808038721 title "Abnormal Blink Reflex and Intermuscular Coherence in Writer's Cramp" @default.
- W2808038721 cites W1515037035 @default.
- W2808038721 cites W1559015476 @default.
- W2808038721 cites W1760402985 @default.
- W2808038721 cites W1983527431 @default.
- W2808038721 cites W1987658377 @default.
- W2808038721 cites W1990303997 @default.
- W2808038721 cites W2007305913 @default.
- W2808038721 cites W2007998352 @default.
- W2808038721 cites W2011873658 @default.
- W2808038721 cites W2016489412 @default.
- W2808038721 cites W2017707400 @default.
- W2808038721 cites W2030741278 @default.
- W2808038721 cites W2032215227 @default.
- W2808038721 cites W2033366153 @default.
- W2808038721 cites W2034381779 @default.
- W2808038721 cites W2036448250 @default.
- W2808038721 cites W2051667078 @default.
- W2808038721 cites W2054911777 @default.
- W2808038721 cites W2069068709 @default.
- W2808038721 cites W2072602941 @default.
- W2808038721 cites W2072852454 @default.
- W2808038721 cites W2073757477 @default.
- W2808038721 cites W2085827527 @default.
- W2808038721 cites W2088739487 @default.
- W2808038721 cites W2094542824 @default.
- W2808038721 cites W2101202648 @default.
- W2808038721 cites W2108406543 @default.
- W2808038721 cites W2111681771 @default.
- W2808038721 cites W2115143932 @default.
- W2808038721 cites W2119432914 @default.
- W2808038721 cites W2119565218 @default.
- W2808038721 cites W2124926586 @default.
- W2808038721 cites W2125050249 @default.
- W2808038721 cites W2130065503 @default.
- W2808038721 cites W2130626695 @default.
- W2808038721 cites W2131051830 @default.
- W2808038721 cites W2131134103 @default.
- W2808038721 cites W2143653869 @default.
- W2808038721 cites W2150331341 @default.
- W2808038721 cites W2151838126 @default.
- W2808038721 cites W2160986206 @default.
- W2808038721 cites W2169654356 @default.
- W2808038721 cites W2172257310 @default.
- W2808038721 cites W2211405960 @default.
- W2808038721 cites W2298131549 @default.
- W2808038721 cites W2345303607 @default.
- W2808038721 cites W2475408975 @default.
- W2808038721 cites W2527852338 @default.
- W2808038721 cites W2553399838 @default.
- W2808038721 cites W2611954557 @default.
- W2808038721 cites W2614687836 @default.
- W2808038721 doi "https://doi.org/10.3389/fneur.2018.00517" @default.
- W2808038721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6037196" @default.
- W2808038721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30013510" @default.
- W2808038721 hasPublicationYear "2018" @default.
- W2808038721 type Work @default.
- W2808038721 sameAs 2808038721 @default.
- W2808038721 citedByCount "11" @default.
- W2808038721 countsByYear W28080387212018 @default.
- W2808038721 countsByYear W28080387212020 @default.
- W2808038721 countsByYear W28080387212021 @default.
- W2808038721 countsByYear W28080387212022 @default.
- W2808038721 countsByYear W28080387212023 @default.
- W2808038721 crossrefType "journal-article" @default.
- W2808038721 hasAuthorship W2808038721A5006213258 @default.
- W2808038721 hasAuthorship W2808038721A5020929906 @default.
- W2808038721 hasAuthorship W2808038721A5024202488 @default.
- W2808038721 hasAuthorship W2808038721A5035320748 @default.
- W2808038721 hasAuthorship W2808038721A5061382191 @default.
- W2808038721 hasAuthorship W2808038721A5062329709 @default.
- W2808038721 hasAuthorship W2808038721A5078896471 @default.
- W2808038721 hasAuthorship W2808038721A5082280984 @default.
- W2808038721 hasBestOaLocation W28080387211 @default.
- W2808038721 hasConcept C126322002 @default.
- W2808038721 hasConcept C15744967 @default.
- W2808038721 hasConcept C169760540 @default.
- W2808038721 hasConcept C2777515770 @default.
- W2808038721 hasConcept C2778559928 @default.
- W2808038721 hasConcept C2780731448 @default.
- W2808038721 hasConcept C42219234 @default.
- W2808038721 hasConcept C46486741 @default.
- W2808038721 hasConcept C548259974 @default.
- W2808038721 hasConcept C551621295 @default.
- W2808038721 hasConcept C71924100 @default.
- W2808038721 hasConcept C83974742 @default.
- W2808038721 hasConcept C99508421 @default.
- W2808038721 hasConceptScore W2808038721C126322002 @default.