FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808054109> ?p ?o ?g. }

• W2808054109 endingPage "482" @default.
• W2808054109 startingPage "476" @default.
• W2808054109 abstract "Greater aortic stiffness and pulse pressure are associated with cerebrovascular remodeling, reduced white matter microstructure, and cognitive performance with aging in humans. However, it is unclear whether aortic stiffness and pulse pressure are associated with reduced basal global cerebral blood flow (CBF) and cerebrovascular reserve among older adults. Global CBF was quantified in 205 adults (range, 19-87 years; mean±SE: 30.6±1.3 years) using quantitative [15O]water brain positron emission tomography imaging. In a subset of older adults (n=24; 70.0±2.0 years), aortic stiffness (carotid femoral pulse wave velocity) and cerebrovascular reserve (change in global CBF after intravenous infusion of acetazolamide) were assessed. In the entire cohort, global CBF was lower in older compared with young adults (36.5±1.1 versus 50.5±0.7 mL/min per 100 mL; P<0.001). Global CBF was higher in young women compared with young men (51.0±0.30 versus 47.4±0.03 mL/min per 100 mL; P<0.001) but did not differ between older women and men (P=0.63). In older adults, greater carotid femoral pulse wave velocity was associated with lower cerebrovascular reserve (r=-0.68; P=0.001 adjusted for age, sex, and mean arterial pressure) but not global CBF (r=0.13; P=0.60). Brachial pulse pressure was not associated with lower cerebrovascular reserve (r=-0.37; P=0.159) when adjusted for age and sex. These data indicate that the age-related increases in aortic stiffness may contribute, in part, to the brain's impaired ability to augment blood flow in response to a stimulus with aging in humans." @default.
• W2808054109 created "2018-06-21" @default.
• W2808054109 creator A5034221747 @default.
• W2808054109 creator A5034739870 @default.
• W2808054109 creator A5039848626 @default.
• W2808054109 creator A5042471559 @default.
• W2808054109 creator A5044311023 @default.
• W2808054109 creator A5081533079 @default.
• W2808054109 date "2018-08-01" @default.
• W2808054109 modified "2023-10-18" @default.
• W2808054109 title "Higher Aortic Stiffness Is Associated With Lower Global Cerebrovascular Reserve Among Older Humans" @default.
• W2808054109 cites W1535253686 @default.
• W2808054109 cites W1992319335 @default.
• W2808054109 cites W2005631588 @default.
• W2808054109 cites W2013342812 @default.
• W2808054109 cites W2016855314 @default.
• W2808054109 cites W2019574826 @default.
• W2808054109 cites W2028507273 @default.
• W2808054109 cites W2033533543 @default.
• W2808054109 cites W2041077485 @default.
• W2808054109 cites W2041441424 @default.
• W2808054109 cites W2044796284 @default.
• W2808054109 cites W2054057072 @default.
• W2808054109 cites W2055048118 @default.
• W2808054109 cites W2057164916 @default.
• W2808054109 cites W2059969387 @default.
• W2808054109 cites W2063920673 @default.
• W2808054109 cites W2070159282 @default.
• W2808054109 cites W2070779463 @default.
• W2808054109 cites W2072030119 @default.
• W2808054109 cites W2075368606 @default.
• W2808054109 cites W2085722058 @default.
• W2808054109 cites W2092534928 @default.
• W2808054109 cites W2094969058 @default.
• W2808054109 cites W2095268962 @default.
• W2808054109 cites W2095294440 @default.
• W2808054109 cites W2102015915 @default.
• W2808054109 cites W2102049075 @default.
• W2808054109 cites W2106072096 @default.
• W2808054109 cites W2110016913 @default.
• W2808054109 cites W2118220635 @default.
• W2808054109 cites W2120206316 @default.
• W2808054109 cites W2125082044 @default.
• W2808054109 cites W2127657747 @default.
• W2808054109 cites W2128329080 @default.
• W2808054109 cites W2143620490 @default.
• W2808054109 cites W2143691602 @default.
• W2808054109 cites W2146609951 @default.
• W2808054109 cites W2147292818 @default.
• W2808054109 cites W2149805981 @default.
• W2808054109 cites W2163107621 @default.
• W2808054109 cites W2163808515 @default.
• W2808054109 cites W2168921082 @default.
• W2808054109 cites W2179003502 @default.
• W2808054109 cites W2234525684 @default.
• W2808054109 cites W2246007286 @default.
• W2808054109 cites W2283904600 @default.
• W2808054109 cites W2294722496 @default.
• W2808054109 cites W2316615891 @default.
• W2808054109 cites W2519937856 @default.
• W2808054109 cites W2543174917 @default.
• W2808054109 cites W2582551642 @default.
• W2808054109 cites W2610653416 @default.
• W2808054109 doi "https://doi.org/10.1161/hypertensionaha.118.11143" @default.
• W2808054109 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6261448" @default.
• W2808054109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29915015" @default.
• W2808054109 hasPublicationYear "2018" @default.
• W2808054109 type Work @default.
• W2808054109 sameAs 2808054109 @default.
• W2808054109 citedByCount "27" @default.
• W2808054109 countsByYear W28080541092018 @default.
• W2808054109 countsByYear W28080541092019 @default.
• W2808054109 countsByYear W28080541092020 @default.
• W2808054109 countsByYear W28080541092021 @default.
• W2808054109 countsByYear W28080541092022 @default.
• W2808054109 countsByYear W28080541092023 @default.
• W2808054109 crossrefType "journal-article" @default.
• W2808054109 hasAuthorship W2808054109A5034221747 @default.
• W2808054109 hasAuthorship W2808054109A5034739870 @default.
• W2808054109 hasAuthorship W2808054109A5039848626 @default.
• W2808054109 hasAuthorship W2808054109A5042471559 @default.
• W2808054109 hasAuthorship W2808054109A5044311023 @default.
• W2808054109 hasAuthorship W2808054109A5081533079 @default.
• W2808054109 hasBestOaLocation W28080541091 @default.
• W2808054109 hasConcept C126322002 @default.
• W2808054109 hasConcept C157767197 @default.
• W2808054109 hasConcept C164705383 @default.
• W2808054109 hasConcept C17140001 @default.
• W2808054109 hasConcept C2775850156 @default.
• W2808054109 hasConcept C2778319312 @default.
• W2808054109 hasConcept C71924100 @default.
• W2808054109 hasConcept C72563966 @default.
• W2808054109 hasConcept C84393581 @default.
• W2808054109 hasConceptScore W2808054109C126322002 @default.
• W2808054109 hasConceptScore W2808054109C157767197 @default.
• W2808054109 hasConceptScore W2808054109C164705383 @default.
• W2808054109 hasConceptScore W2808054109C17140001 @default.
• W2808054109 hasConceptScore W2808054109C2775850156 @default.

• next