Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808058666> ?p ?o ?g. }
- W2808058666 endingPage "11" @default.
- W2808058666 startingPage "1" @default.
- W2808058666 abstract "Sensorineural hearing loss is caused by the loss of sensory hair cells (HCs) or a damaged afferent nerve pathway to the auditory cortex. The most common option for the treatment of sensorineural hearing loss is hearing rehabilitation using hearing devices. Various kinds of hearing devices are available but, despite recent advancements, their perceived sound quality does not mimic that of the naïve cochlea. Damage to crucial cochlear structures is mostly irreversible and results in permanent hearing loss. Cochlear HC regeneration has long been an important goal in the field of hearing research. However, it remains challenging because, thus far, no medical treatment has successfully regenerated cochlear HCs. Recent advances in genetic modulation and developmental techniques have led to novel approaches to generating HCs or protecting against HC loss, to preserve hearing. In this review, we present and review the current status of two different approaches to restoring or protecting hearing, gene therapy, including the newly introduced CRISPR/Cas9 genome editing, and stem cell therapy, and suggest the future direction." @default.
- W2808058666 created "2018-06-21" @default.
- W2808058666 creator A5062686135 @default.
- W2808058666 creator A5077498941 @default.
- W2808058666 date "2018-06-13" @default.
- W2808058666 modified "2023-09-29" @default.
- W2808058666 title "Potential of Gene and Cell Therapy for Inner Ear Hair Cells" @default.
- W2808058666 cites W1049405896 @default.
- W2808058666 cites W134089957 @default.
- W2808058666 cites W1486737937 @default.
- W2808058666 cites W1647075334 @default.
- W2808058666 cites W1755815992 @default.
- W2808058666 cites W1861297144 @default.
- W2808058666 cites W1961744561 @default.
- W2808058666 cites W1967800133 @default.
- W2808058666 cites W1971014753 @default.
- W2808058666 cites W1974861468 @default.
- W2808058666 cites W1975949784 @default.
- W2808058666 cites W1981410060 @default.
- W2808058666 cites W1985551370 @default.
- W2808058666 cites W1985835614 @default.
- W2808058666 cites W1988672563 @default.
- W2808058666 cites W1992857468 @default.
- W2808058666 cites W1994558354 @default.
- W2808058666 cites W1995793532 @default.
- W2808058666 cites W1996301914 @default.
- W2808058666 cites W1998209096 @default.
- W2808058666 cites W1999400287 @default.
- W2808058666 cites W1999633987 @default.
- W2808058666 cites W2003403183 @default.
- W2808058666 cites W2003445994 @default.
- W2808058666 cites W2004136595 @default.
- W2808058666 cites W2004902965 @default.
- W2808058666 cites W2006591300 @default.
- W2808058666 cites W2009133456 @default.
- W2808058666 cites W2010929275 @default.
- W2808058666 cites W2014285290 @default.
- W2808058666 cites W2016667404 @default.
- W2808058666 cites W2017068359 @default.
- W2808058666 cites W2020653679 @default.
- W2808058666 cites W2021088854 @default.
- W2808058666 cites W2026120980 @default.
- W2808058666 cites W2026545561 @default.
- W2808058666 cites W2028916500 @default.
- W2808058666 cites W2034060287 @default.
- W2808058666 cites W2040078726 @default.
- W2808058666 cites W2047307155 @default.
- W2808058666 cites W2047481904 @default.
- W2808058666 cites W2049365404 @default.
- W2808058666 cites W2049442129 @default.
- W2808058666 cites W2050001418 @default.
- W2808058666 cites W2055353965 @default.
- W2808058666 cites W2056390254 @default.
- W2808058666 cites W2060516472 @default.
- W2808058666 cites W2063464173 @default.
- W2808058666 cites W2066161967 @default.
- W2808058666 cites W2068019147 @default.
- W2808058666 cites W2073217307 @default.
- W2808058666 cites W2074860914 @default.
- W2808058666 cites W2075136399 @default.
- W2808058666 cites W2081149580 @default.
- W2808058666 cites W2084082669 @default.
- W2808058666 cites W2085890965 @default.
- W2808058666 cites W2086496995 @default.
- W2808058666 cites W2088523571 @default.
- W2808058666 cites W2091020339 @default.
- W2808058666 cites W2094916525 @default.
- W2808058666 cites W2100706309 @default.
- W2808058666 cites W2105106090 @default.
- W2808058666 cites W2105881005 @default.
- W2808058666 cites W2107880845 @default.
- W2808058666 cites W2116494713 @default.
- W2808058666 cites W2118638606 @default.
- W2808058666 cites W2119212619 @default.
- W2808058666 cites W2128063844 @default.
- W2808058666 cites W2138317563 @default.
- W2808058666 cites W2140348457 @default.
- W2808058666 cites W2141569557 @default.
- W2808058666 cites W2145520556 @default.
- W2808058666 cites W2155161284 @default.
- W2808058666 cites W2210702367 @default.
- W2808058666 cites W2262231968 @default.
- W2808058666 cites W2288535778 @default.
- W2808058666 cites W2295573618 @default.
- W2808058666 cites W2339695142 @default.
- W2808058666 cites W241491381 @default.
- W2808058666 cites W2460268262 @default.
- W2808058666 cites W2494602139 @default.
- W2808058666 cites W2502831104 @default.
- W2808058666 cites W2507385820 @default.
- W2808058666 cites W2529514452 @default.
- W2808058666 cites W2562167215 @default.
- W2808058666 cites W2586762515 @default.
- W2808058666 cites W2604350065 @default.
- W2808058666 cites W2605246466 @default.
- W2808058666 cites W2615170376 @default.
- W2808058666 cites W2625520849 @default.
- W2808058666 cites W2727250954 @default.