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- W2808067519 abstract "The spatial positioning of genes throughout the genome arrangement can alter their expression in many eukaryotic organisms. Often this results in a genomic context-specific effect on transcription. One example of this is through the clustering of functionally related genes, which results in adjacent-gene coregulation in the budding yeast Saccharomyces cerevisiae . In the present study, we set out to systematically characterize the prevalence of this phenomenon, finding the genomic organization of functionally related genes into clusters is a characteristic of myriad gene families. These arrangements are found in many evolutionarily divergent fungi and thus represent a widespread, yet underappreciated, layer of transcriptional regulation." @default.
- W2808067519 created "2018-06-21" @default.
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- W2808067519 date "2018-06-27" @default.
- W2808067519 modified "2023-10-16" @default.
- W2808067519 title "Systematic Identification, Characterization, and Conservation of Adjacent-Gene Coregulation in the Budding Yeast Saccharomyces cerevisiae" @default.
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- W2808067519 doi "https://doi.org/10.1128/msphere.00220-18" @default.
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