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• W2808098932 abstract "INTRODUCTION: Dacryocystitis is inflammation of the lacrimal sac usuallysecondary to obstruction of the nasolacrimal duct. The lacrimal drainageapparatus is an effective system for drainage of tears. When there isobstruction in the drainage apparatus, there is stasis of sac contents whichforms a reservoir for development of infection. The close association ofconjunctival and nasal mucosa with the sac makes it more prone toinfection. The most common sources of infection are the nose, paranasalsinuses and pericystic tissues. AIM OF THE STUDY: 1. To analyse the bacterial etiology in cases of chronic dacryocystitisreported at a tertiary level hospital.2. To assess the association of chronic dacryocystitis with age, sex ofpatient, duration of symptoms and laterality.3. To determine their invitro susceptibilities and resistance toAntibiotics. MATERIALS AND METHODS: The study of microbiological profile in chronic dacryocystitis andtheir susceptibility and resistance to antibiotics in South Tamil Nadu wascarried out in the Department of Ophthalmology, Tirunelveli MedicalCollege, Tirunelveli.Settings : Ophthalmology ward, microbiological labStudy design : Single centre observational prospective hospitalbased studyPeriod of study : June 2009 to June 2010Ethical approval : ObtainedTirunelveli Medical College Hospital is a tertiary care centre inSouth Tamil Nadu. The patient population is a fairly representativesample of the disease pattern in this region. Inclusion Criteria:Patients between 16-80 years of age.All patients with complaints of mucopurulent discharge, epiphora,and sac abscess were included in this study. Exclusion Criteria:Patients less than 16 years of age.Patients with acute dacryocystitis, lacrimal abscess and mucocelewere excluded from the study. Those who have been treated with systemic or topical antibioticswithin 1 week of presentation were excluded from the study.All cases of pseudoepiphora and epiphora caused by diagnosesother than nasolacrimal duct obstruction were also excluded from thisstudy. OBSERVATION AND RESULTS: An observational prospective study of the microbiological profilein chronic dacryocystitis and their susceptibility and resistance toantibiotics was carried out at Tirunelveli Medical College Hospital. Atotal of 110 eyes of 100 patients were studied in respect of their meanage, sex, duration of symptoms, patency of duct, microbiological profile,antibiotic susceptibility and treatment procedures. Of the 100 patients 36were males and 64 were females. The mean age of presentation ofchronic dacryocystitis among males was 62.2 + 13.8 whereas that amongfemales was 59.5 + 12.8. A total of 200 eyes of 100 patients wereconsidered and on syringing 110 had regurgitation of pus, 37 hadregurgitation of clear fluid and 53 ducts were patent. Of the 110 eyes withinfection positive culture was obtained from 85 (77.3%) eyes and nogrowth was observed in 25 (22.7%) eyes. A total of 92 (83.6%) eyesunderwent DCT and 18 (16.4%) eyes underwent DCR. The patients werefollowed up and found to be asymptomatic. CONCLUSION: In our study, incidence of chronic dacryocystitis was found more infemales than males, the mean age of presentation was 60.5+13.2 years,most of the patients presented to us within 10 months of the onset ofsymptoms. DCT was done in 92 eyes and DCR was done 18 eyes. Themost common micro organism isolated was Coagulase negativeStaphylococcus followed Staphylococcus aureus & Streptococcusspecies. Gram positive organisms showed highest sensitivity toGatifloxacin , Moxifloxacin and Gram negative organisms to Cefazolin .The high rate of micro-organism positive cultures suggests that adultpatients should be treated for their lacrimal sac infection before anyintraocular surgery because of the potential risk of post operativeinfection. Bacterial flora is abundant at the eyelid margin and the settingis conducive to a possible spontaneous mutation that can cause antibioticresistance. Hence a prudent use of antibiotics is essential. Unnecessaryusage of antibiotic leads to emergence of resistance. Thus in cases ofregurgitation it is better to use Gatifloxacin or Moxifloxacin as they aremore effective." @default.
• W2808098932 created "2018-06-21" @default.
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• W2808098932 date "2011-04-01" @default.
• W2808098932 modified "2023-09-26" @default.
• W2808098932 title "A study of the microbiological profile in chronic dacryocystitis." @default.
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