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• W2808258785 abstract "A new Passerini-type reaction in which hexafluoroisopropanol functions as the acid component is reported. The reaction tolerates a broad range of isocyanides and aldehydes, and the formed imidates can be reduced toward β-amino alcohols under mild and metal-free conditions. In addition, the imidate products were shown to undergo an unprecedented retro-Passerini-type reaction under microwave conditions, providing valuable mechanistic information about the Passerini reaction and its variations." @default.
• W2808258785 created "2018-06-21" @default.
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• W2808258785 date "2018-06-15" @default.
• W2808258785 modified "2023-10-18" @default.
• W2808258785 title "Hexafluoroisopropanol as the Acid Component in the Passerini Reaction: One-Pot Access to β-Amino Alcohols" @default.
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• W2808258785 doi "https://doi.org/10.1021/acs.orglett.8b01561" @default.
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