Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808412658> ?p ?o ?g. }
- W2808412658 endingPage "196" @default.
- W2808412658 startingPage "183" @default.
- W2808412658 abstract "An obesogenic environment during pregnancy has been shown to increase the risk of dysregulation on adipogenesis and insulin resistance in the offspring. Being essential for the growing fetus, glucose supply is guaranteed by a number of modifications in the mother’s metabolism, and thus, glucose control during pregnancy especially among obese or diabetic women is paramount to prevent adverse consequences in their children. Besides the election of low-glycemic-index carbohydrates, the rate of carbohydrate digestion could be relevant to keep a good glucose control. In the present study, we compared the effects of two high-fat diets with similar glycemic load but different rates of carbohydrate digestion given to pregnant insulin-resistant rats. After birth, all animals were fed a standard diet until age 14 weeks. We analyzed offspring body composition, plasma and adipocyte lipidomics, lipid metabolism in adipose tissue and insulin sensitivity. Those animals whose mothers were fed the rapid-digesting carbohydrate diet exhibited an excessive adipogenesis. Thus, these animals showed a marked lipidemia, increased lipid synthesis in the adipose tissue and reduced glucose transporter amount in the adipose. On the contrary, those animals whose mothers were fed the slow-digesting carbohydrate diet showed a profile in the measured parameters closer to that of the offspring of healthy mothers. These results support the hypothesis that not only glycemic index but the rate of carbohydrate digestion during gestation may be critical to regulate the programming of adipogenesis in the offspring." @default.
- W2808412658 created "2018-06-21" @default.
- W2808412658 creator A5000029388 @default.
- W2808412658 creator A5001516669 @default.
- W2808412658 creator A5024527453 @default.
- W2808412658 creator A5029629480 @default.
- W2808412658 creator A5036812594 @default.
- W2808412658 creator A5047498629 @default.
- W2808412658 creator A5050163820 @default.
- W2808412658 creator A5050662260 @default.
- W2808412658 creator A5055082002 @default.
- W2808412658 creator A5069718644 @default.
- W2808412658 creator A5075834641 @default.
- W2808412658 creator A5085603716 @default.
- W2808412658 date "2018-11-01" @default.
- W2808412658 modified "2023-10-17" @default.
- W2808412658 title "Feeding a slowly digestible carbohydrate diet during pregnancy of insulin-resistant rats prevents the excess of adipogenesis in their offspring" @default.
- W2808412658 cites W1490331581 @default.
- W2808412658 cites W1500403865 @default.
- W2808412658 cites W1544424813 @default.
- W2808412658 cites W1563149938 @default.
- W2808412658 cites W1592674309 @default.
- W2808412658 cites W1628351137 @default.
- W2808412658 cites W1831301545 @default.
- W2808412658 cites W1863728472 @default.
- W2808412658 cites W1892418147 @default.
- W2808412658 cites W1954270231 @default.
- W2808412658 cites W1963632908 @default.
- W2808412658 cites W1964385823 @default.
- W2808412658 cites W1973017243 @default.
- W2808412658 cites W1978648325 @default.
- W2808412658 cites W1979324338 @default.
- W2808412658 cites W1979594456 @default.
- W2808412658 cites W1979915761 @default.
- W2808412658 cites W1988457908 @default.
- W2808412658 cites W1989294105 @default.
- W2808412658 cites W1989402296 @default.
- W2808412658 cites W1992292929 @default.
- W2808412658 cites W2011792719 @default.
- W2808412658 cites W2011953107 @default.
- W2808412658 cites W2012037560 @default.
- W2808412658 cites W2013857037 @default.
- W2808412658 cites W2014662793 @default.
- W2808412658 cites W2019916333 @default.
- W2808412658 cites W2030328205 @default.
- W2808412658 cites W2033622876 @default.
- W2808412658 cites W2036442486 @default.
- W2808412658 cites W2040384492 @default.
- W2808412658 cites W2043498652 @default.
- W2808412658 cites W2051827443 @default.
- W2808412658 cites W2058204099 @default.
- W2808412658 cites W2065504943 @default.
- W2808412658 cites W2065589065 @default.
- W2808412658 cites W2073695538 @default.
- W2808412658 cites W2075023376 @default.
- W2808412658 cites W2077298946 @default.
- W2808412658 cites W2078562982 @default.
- W2808412658 cites W2079120799 @default.
- W2808412658 cites W2083321610 @default.
- W2808412658 cites W2083370558 @default.
- W2808412658 cites W2100198908 @default.
- W2808412658 cites W2103869703 @default.
- W2808412658 cites W2105532009 @default.
- W2808412658 cites W2107904389 @default.
- W2808412658 cites W2108450638 @default.
- W2808412658 cites W2108904664 @default.
- W2808412658 cites W2109180944 @default.
- W2808412658 cites W2114949397 @default.
- W2808412658 cites W2124857707 @default.
- W2808412658 cites W2126325316 @default.
- W2808412658 cites W2127908134 @default.
- W2808412658 cites W2131918620 @default.
- W2808412658 cites W2135977165 @default.
- W2808412658 cites W2136620978 @default.
- W2808412658 cites W2141989748 @default.
- W2808412658 cites W2148116175 @default.
- W2808412658 cites W2148352901 @default.
- W2808412658 cites W2155805365 @default.
- W2808412658 cites W2156448275 @default.
- W2808412658 cites W2160763536 @default.
- W2808412658 cites W2166897446 @default.
- W2808412658 cites W2168122159 @default.
- W2808412658 cites W2168341804 @default.
- W2808412658 cites W2171761708 @default.
- W2808412658 cites W2171952619 @default.
- W2808412658 cites W2206767133 @default.
- W2808412658 cites W2219179497 @default.
- W2808412658 cites W2290617066 @default.
- W2808412658 cites W2290753751 @default.
- W2808412658 cites W2444481702 @default.
- W2808412658 cites W2462636387 @default.
- W2808412658 cites W2623455668 @default.
- W2808412658 cites W4253215822 @default.
- W2808412658 cites W50495963 @default.
- W2808412658 cites W935688119 @default.
- W2808412658 doi "https://doi.org/10.1016/j.jnutbio.2018.05.018" @default.
- W2808412658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30253280" @default.
- W2808412658 hasPublicationYear "2018" @default.