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- W2808416723 abstract "The respiratory network of the preBötzinger complex (preBötC), which controls inspiratory behavior, can in normal conditions simultaneously produce two types of inspiration-related rhythmic activities: the eupneic rhythm composed of monophasic, low-amplitude, and relatively high-frequency bursts, interspersed with sigh rhythmic activity, composed of biphasic, high-amplitude, and lower frequency bursts. By combining electrophysiological recordings from transverse brainstem slices with computational modeling, new advances in the mechanisms underlying sigh production have been obtained during prenatal development. The present review summarizes recent findings that establish when sigh rhythmogenesis starts to be produced during embryonic development as well as the cellular, membrane, and synaptic properties required for its expression. Together, the results demonstrate that although generated by the same network, the eupnea and sigh rhythms have different developmental onset times and rely on distinct network properties. Because sighs (also known as augmented breaths) are important in maintaining lung function (by reopening collapsed alveoli), gaining insight into their underlying neural mechanisms at early developmental stages is likely to help in the treatment of prematurely born babies often suffering from breathing deficiencies." @default.
- W2808416723 created "2018-06-21" @default.
- W2808416723 creator A5056515397 @default.
- W2808416723 date "2018-09-01" @default.
- W2808416723 modified "2023-10-18" @default.
- W2808416723 title "Neural mechanisms for sigh generation during prenatal development" @default.
- W2808416723 cites W1480591440 @default.
- W2808416723 cites W1481989309 @default.
- W2808416723 cites W1529085124 @default.
- W2808416723 cites W1552557439 @default.
- W2808416723 cites W1574842928 @default.
- W2808416723 cites W1588629441 @default.
- W2808416723 cites W1599531759 @default.
- W2808416723 cites W1827504322 @default.
- W2808416723 cites W1923435653 @default.
- W2808416723 cites W1940376800 @default.
- W2808416723 cites W1947095866 @default.
- W2808416723 cites W1973530752 @default.
- W2808416723 cites W1977239542 @default.
- W2808416723 cites W1977546294 @default.
- W2808416723 cites W1979296509 @default.
- W2808416723 cites W1982848535 @default.
- W2808416723 cites W1997107200 @default.
- W2808416723 cites W2000101627 @default.
- W2808416723 cites W2002701925 @default.
- W2808416723 cites W2002775981 @default.
- W2808416723 cites W2003827347 @default.
- W2808416723 cites W2005480414 @default.
- W2808416723 cites W2006410388 @default.
- W2808416723 cites W2013613467 @default.
- W2808416723 cites W2015220748 @default.
- W2808416723 cites W2016151414 @default.
- W2808416723 cites W2016956534 @default.
- W2808416723 cites W2017728979 @default.
- W2808416723 cites W2019909157 @default.
- W2808416723 cites W2028043512 @default.
- W2808416723 cites W2030213496 @default.
- W2808416723 cites W2030673491 @default.
- W2808416723 cites W2032335526 @default.
- W2808416723 cites W2035772981 @default.
- W2808416723 cites W2037233574 @default.
- W2808416723 cites W2037688283 @default.
- W2808416723 cites W2038199636 @default.
- W2808416723 cites W2042101174 @default.
- W2808416723 cites W2043610459 @default.
- W2808416723 cites W2052046488 @default.
- W2808416723 cites W2052454896 @default.
- W2808416723 cites W2054914622 @default.
- W2808416723 cites W2058965831 @default.
- W2808416723 cites W2059803012 @default.
- W2808416723 cites W2063812431 @default.
- W2808416723 cites W2064363302 @default.
- W2808416723 cites W2067359818 @default.
- W2808416723 cites W2069280878 @default.
- W2808416723 cites W2070687545 @default.
- W2808416723 cites W2071878820 @default.
- W2808416723 cites W2072139971 @default.
- W2808416723 cites W2072685125 @default.
- W2808416723 cites W2078962782 @default.
- W2808416723 cites W2079140754 @default.
- W2808416723 cites W2081864985 @default.
- W2808416723 cites W2082746559 @default.
- W2808416723 cites W2083248454 @default.
- W2808416723 cites W2090449601 @default.
- W2808416723 cites W2093601288 @default.
- W2808416723 cites W2100046131 @default.
- W2808416723 cites W2103479712 @default.
- W2808416723 cites W2104129416 @default.
- W2808416723 cites W2104700386 @default.
- W2808416723 cites W2108815207 @default.
- W2808416723 cites W2108957007 @default.
- W2808416723 cites W2112403446 @default.
- W2808416723 cites W2120070895 @default.
- W2808416723 cites W2125133184 @default.
- W2808416723 cites W2126852048 @default.
- W2808416723 cites W2142836533 @default.
- W2808416723 cites W2149621932 @default.
- W2808416723 cites W2151686843 @default.
- W2808416723 cites W2156947381 @default.
- W2808416723 cites W2157084135 @default.
- W2808416723 cites W2261288281 @default.
- W2808416723 cites W2263650999 @default.
- W2808416723 cites W2272447725 @default.
- W2808416723 cites W2314295118 @default.
- W2808416723 cites W2336650430 @default.
- W2808416723 cites W2340199301 @default.
- W2808416723 cites W2346625225 @default.
- W2808416723 cites W2400226261 @default.
- W2808416723 cites W2418219191 @default.
- W2808416723 cites W2461165059 @default.
- W2808416723 cites W2461208797 @default.
- W2808416723 cites W2487813642 @default.
- W2808416723 cites W2505292440 @default.
- W2808416723 cites W2510966112 @default.
- W2808416723 cites W2792962347 @default.
- W2808416723 doi "https://doi.org/10.1152/jn.00314.2018" @default.
- W2808416723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29897860" @default.
- W2808416723 hasPublicationYear "2018" @default.