Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808452891> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2808452891 endingPage "986" @default.
- W2808452891 startingPage "981" @default.
- W2808452891 abstract "The aim of this study was to investigate the changes in insular cortex metabolites and the correlation with clinical manifestations in patients with obstructive sleep apnea syndrome (OSA). Lateral insular metabolite levels were measured and relevant ratios were calculated in OSA patients and healthy individuals, including N-acetyl aspartate/creatine (NAA/Cr), choline/creatine (Cho/Cr), inositol/creatine (Ins/Cr), glutamate compound/creatine (Glx/Cr), N-acetyl aspartate/choline (NAA/Cho), and lactic acid (Lac). Participants' scores on the Hamilton Anxiety Scale (HAMA), the Hamilton Depression Scale (HAMD), the Pittsburgh Sleep Quality Index (PSQI), and the Epworth Sleepiness Scale (ESS) were also evaluated. Apnea-Hypopnea Index, the lowest arterial oxygen saturation, and the mean arterial oxygen saturation (MSaO2) values were monitored by polysomnography. NAA/Cr, Glx/Cr, and NAA/Cho values in the insular cortex were significantly decreased, whereas HAMA, HAMD, PSQI, and ESS scores were significantly higher in OSA patients compared with the control participants. HAMA and HAMD scores showed a significant negative correlation with the NAA/Cho value in the insular cortex and a positive correlation with PSQI and ESS scores. PSQI scores were correlated positively with the Cho/Cr and Ins/Cr ratios in the left insular cortex, but correlated negatively with the NAA/Cho ratio. The symptoms of anxiety and depression in OSA patients may be associated with insular neuron damage or dysfunction; proton magnetic resonance spectroscopy can provide an objective imaging basis for the early diagnosis and treatment of OSA in clinical practice." @default.
- W2808452891 created "2018-06-21" @default.
- W2808452891 creator A5042097425 @default.
- W2808452891 creator A5045507242 @default.
- W2808452891 creator A5080754945 @default.
- W2808452891 date "2018-08-15" @default.
- W2808452891 modified "2023-09-26" @default.
- W2808452891 title "Changes in insular cortex metabolites in patients with obstructive sleep apnea syndrome" @default.
- W2808452891 cites W197066864 @default.
- W2808452891 cites W1984169272 @default.
- W2808452891 cites W2017334217 @default.
- W2808452891 cites W2038083991 @default.
- W2808452891 cites W2078453165 @default.
- W2808452891 cites W2084843056 @default.
- W2808452891 cites W2088375959 @default.
- W2808452891 cites W2097718659 @default.
- W2808452891 cites W2114613490 @default.
- W2808452891 cites W2120322642 @default.
- W2808452891 cites W2120824707 @default.
- W2808452891 cites W2151487996 @default.
- W2808452891 cites W2152161319 @default.
- W2808452891 cites W2160070901 @default.
- W2808452891 cites W2162688500 @default.
- W2808452891 cites W2288071963 @default.
- W2808452891 cites W2345093062 @default.
- W2808452891 cites W632142678 @default.
- W2808452891 doi "https://doi.org/10.1097/wnr.0000000000001065" @default.
- W2808452891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29912850" @default.
- W2808452891 hasPublicationYear "2018" @default.
- W2808452891 type Work @default.
- W2808452891 sameAs 2808452891 @default.
- W2808452891 citedByCount "10" @default.
- W2808452891 countsByYear W28084528912018 @default.
- W2808452891 countsByYear W28084528912020 @default.
- W2808452891 countsByYear W28084528912021 @default.
- W2808452891 countsByYear W28084528912023 @default.
- W2808452891 crossrefType "journal-article" @default.
- W2808452891 hasAuthorship W2808452891A5042097425 @default.
- W2808452891 hasAuthorship W2808452891A5045507242 @default.
- W2808452891 hasAuthorship W2808452891A5080754945 @default.
- W2808452891 hasConcept C118552586 @default.
- W2808452891 hasConcept C126322002 @default.
- W2808452891 hasConcept C134018914 @default.
- W2808452891 hasConcept C2776006263 @default.
- W2808452891 hasConcept C2777198177 @default.
- W2808452891 hasConcept C2777711342 @default.
- W2808452891 hasConcept C2778205975 @default.
- W2808452891 hasConcept C2779896295 @default.
- W2808452891 hasConcept C2780539906 @default.
- W2808452891 hasConcept C2781123555 @default.
- W2808452891 hasConcept C2781326671 @default.
- W2808452891 hasConcept C3018023364 @default.
- W2808452891 hasConcept C71924100 @default.
- W2808452891 hasConcept C90924648 @default.
- W2808452891 hasConceptScore W2808452891C118552586 @default.
- W2808452891 hasConceptScore W2808452891C126322002 @default.
- W2808452891 hasConceptScore W2808452891C134018914 @default.
- W2808452891 hasConceptScore W2808452891C2776006263 @default.
- W2808452891 hasConceptScore W2808452891C2777198177 @default.
- W2808452891 hasConceptScore W2808452891C2777711342 @default.
- W2808452891 hasConceptScore W2808452891C2778205975 @default.
- W2808452891 hasConceptScore W2808452891C2779896295 @default.
- W2808452891 hasConceptScore W2808452891C2780539906 @default.
- W2808452891 hasConceptScore W2808452891C2781123555 @default.
- W2808452891 hasConceptScore W2808452891C2781326671 @default.
- W2808452891 hasConceptScore W2808452891C3018023364 @default.
- W2808452891 hasConceptScore W2808452891C71924100 @default.
- W2808452891 hasConceptScore W2808452891C90924648 @default.
- W2808452891 hasIssue "12" @default.
- W2808452891 hasLocation W28084528911 @default.
- W2808452891 hasLocation W28084528912 @default.
- W2808452891 hasOpenAccess W2808452891 @default.
- W2808452891 hasPrimaryLocation W28084528911 @default.
- W2808452891 hasRelatedWork W2383496458 @default.
- W2808452891 hasRelatedWork W2385244159 @default.
- W2808452891 hasRelatedWork W2385652705 @default.
- W2808452891 hasRelatedWork W2389447091 @default.
- W2808452891 hasRelatedWork W2390361370 @default.
- W2808452891 hasRelatedWork W2393836077 @default.
- W2808452891 hasRelatedWork W2394005338 @default.
- W2808452891 hasRelatedWork W2405235165 @default.
- W2808452891 hasRelatedWork W2565067826 @default.
- W2808452891 hasRelatedWork W3029059033 @default.
- W2808452891 hasVolume "29" @default.
- W2808452891 isParatext "false" @default.
- W2808452891 isRetracted "false" @default.
- W2808452891 magId "2808452891" @default.
- W2808452891 workType "article" @default.