Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808498304> ?p ?o ?g. }
- W2808498304 endingPage "1419" @default.
- W2808498304 startingPage "1419" @default.
- W2808498304 abstract "Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties. Experimental and computational studies have reported on the therapeutic potential of polyamidoamine (PAMAM) dendrimers as solubility enhancers in pre-clinical and clinical settings. Besides formulation strategies, factors such as pH, PAMAM dendrimer generation, PAMAM dendrimer concentration, nature of the PAMAM core, special ligand and surface modifications of PAMAM dendrimer have an influence on drug solubility and other recommendable pharmacological properties. This review, therefore, compiles the recently reported applications of PAMAM dendrimers in pre-clinical and clinical uses as enhancers of solubility and other desirable properties such as sustained and controlled release, bioavailability, bio-distribution, toxicity reduction or enhancement, and targeted delivery of small molecules with emphasis on cancer treatment." @default.
- W2808498304 created "2018-06-21" @default.
- W2808498304 creator A5013486980 @default.
- W2808498304 creator A5036275485 @default.
- W2808498304 creator A5039742773 @default.
- W2808498304 creator A5044649307 @default.
- W2808498304 creator A5083595555 @default.
- W2808498304 date "2018-06-12" @default.
- W2808498304 modified "2023-09-29" @default.
- W2808498304 title "Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies" @default.
- W2808498304 cites W1592387620 @default.
- W2808498304 cites W1606991268 @default.
- W2808498304 cites W1770710039 @default.
- W2808498304 cites W1965476230 @default.
- W2808498304 cites W1971718983 @default.
- W2808498304 cites W1981116681 @default.
- W2808498304 cites W1994936258 @default.
- W2808498304 cites W1995529190 @default.
- W2808498304 cites W2010487775 @default.
- W2808498304 cites W2012580789 @default.
- W2808498304 cites W2026554295 @default.
- W2808498304 cites W2033857478 @default.
- W2808498304 cites W2056180004 @default.
- W2808498304 cites W2068126429 @default.
- W2808498304 cites W2072952339 @default.
- W2808498304 cites W2073439757 @default.
- W2808498304 cites W2074440259 @default.
- W2808498304 cites W2075343248 @default.
- W2808498304 cites W2080876222 @default.
- W2808498304 cites W2088828170 @default.
- W2808498304 cites W2089010917 @default.
- W2808498304 cites W2113685381 @default.
- W2808498304 cites W2129373144 @default.
- W2808498304 cites W2138994120 @default.
- W2808498304 cites W2149076882 @default.
- W2808498304 cites W2150458127 @default.
- W2808498304 cites W2151823004 @default.
- W2808498304 cites W2153068313 @default.
- W2808498304 cites W2155417559 @default.
- W2808498304 cites W2162250373 @default.
- W2808498304 cites W2209620742 @default.
- W2808498304 cites W2290638321 @default.
- W2808498304 cites W2328831958 @default.
- W2808498304 cites W2399675795 @default.
- W2808498304 cites W2409403086 @default.
- W2808498304 cites W2415245575 @default.
- W2808498304 cites W2480651174 @default.
- W2808498304 cites W2488465963 @default.
- W2808498304 cites W2507121191 @default.
- W2808498304 cites W2508926171 @default.
- W2808498304 cites W251187055 @default.
- W2808498304 cites W2513765623 @default.
- W2808498304 cites W2522460525 @default.
- W2808498304 cites W2560267324 @default.
- W2808498304 cites W2577678328 @default.
- W2808498304 cites W2582311069 @default.
- W2808498304 cites W2600452401 @default.
- W2808498304 cites W2604684304 @default.
- W2808498304 cites W2612651705 @default.
- W2808498304 cites W2613352137 @default.
- W2808498304 cites W2614780414 @default.
- W2808498304 cites W2614857817 @default.
- W2808498304 cites W2702551048 @default.
- W2808498304 cites W2749722012 @default.
- W2808498304 cites W2759602013 @default.
- W2808498304 cites W2761493287 @default.
- W2808498304 cites W2765819036 @default.
- W2808498304 cites W2771650489 @default.
- W2808498304 cites W2778583677 @default.
- W2808498304 cites W2793842581 @default.
- W2808498304 cites W2795693074 @default.
- W2808498304 cites W4251153665 @default.
- W2808498304 cites W4378171839 @default.
- W2808498304 cites W911267903 @default.
- W2808498304 doi "https://doi.org/10.3390/molecules23061419" @default.
- W2808498304 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6100328" @default.
- W2808498304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29895742" @default.
- W2808498304 hasPublicationYear "2018" @default.
- W2808498304 type Work @default.
- W2808498304 sameAs 2808498304 @default.
- W2808498304 citedByCount "35" @default.
- W2808498304 countsByYear W28084983042018 @default.
- W2808498304 countsByYear W28084983042019 @default.
- W2808498304 countsByYear W28084983042020 @default.
- W2808498304 countsByYear W28084983042021 @default.
- W2808498304 countsByYear W28084983042022 @default.
- W2808498304 countsByYear W28084983042023 @default.
- W2808498304 crossrefType "journal-article" @default.
- W2808498304 hasAuthorship W2808498304A5013486980 @default.
- W2808498304 hasAuthorship W2808498304A5036275485 @default.
- W2808498304 hasAuthorship W2808498304A5039742773 @default.
- W2808498304 hasAuthorship W2808498304A5044649307 @default.
- W2808498304 hasAuthorship W2808498304A5083595555 @default.
- W2808498304 hasBestOaLocation W28084983041 @default.
- W2808498304 hasConcept C155574463 @default.
- W2808498304 hasConcept C161624437 @default.
- W2808498304 hasConcept C171250308 @default.
- W2808498304 hasConcept C178790620 @default.