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- W2808583997 abstract "Abstract Intrinsically integrating precise diagnosis, effective therapy, and self‐anti‐inflammatory action into a single nanoparticle is attractive for tumor treatment and future clinical application, but still remains a great challenge. In this study, bovine serum albumin–iridium oxide nanoparticles (BSA‐IrO 2 NPs) with extraordinary photothermal conversion efficiency, good photocatalytic activity, and a high X‐ray absorption coefficient were prepared through one‐step biomineralization. The nanoparticles allow tumor phototherapy and simultaneous photoacoustic/thermal imaging and computed tomography. More importantly, BSA‐IrO 2 NPs can also act as a catalase to protect normal cells against H 2 O 2 ‐induced reactive oxygen pressure and inflammation while significantly enhancing photoacoustic imaging through microbubble‐based inertial cavitation. These remarkable features may open up the exploration iridium‐based nanomaterials in theranostics." @default.
- W2808583997 created "2018-06-21" @default.
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- W2808583997 date "2018-07-12" @default.
- W2808583997 modified "2023-10-16" @default.
- W2808583997 title "BSA‐IrO<sub>2</sub>: Catalase‐like Nanoparticles with High Photothermal Conversion Efficiency and a High X‐ray Absorption Coefficient for Anti‐inflammation and Antitumor Theranostics" @default.
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- W2808583997 doi "https://doi.org/10.1002/anie.201804466" @default.
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