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- W2808615568 abstract "Diabetic ketoacidosis constitutes a profound metabolic disturbance of energy homeostasis with a distinct biochemical profile that is characterized by hyperglycemia, ketonemia, metabolic acidosis, and electrolyte abnormalities. It is caused by deficiency of insulin, the hallmark of type 1 diabetes mellitus. The typical symptoms and signs — polyuria, ketotic breath, and Kussmaul respirations — reflect biochemical and molecular processes caused by insulin deficiency and counterregulatory hormones, as described in recent reviews.1-3 Despite such knowledge, 30 to 50% of all children with new-onset type 1 diabetes have diabetic ketoacidosis at the time of diagnosis, even in highly developed countries.3 Programs that heighten . . ." @default.
- W2808615568 created "2018-06-21" @default.
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- W2808615568 date "2018-06-14" @default.
- W2808615568 modified "2023-09-25" @default.
- W2808615568 title "Fluid Composition, Infusion Rate, and Brain Injury in Diabetic Ketoacidosis" @default.
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- W2808615568 doi "https://doi.org/10.1056/nejme1806017" @default.
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