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• W2808941133 abstract "N-Methyl carbamoylimidazole is a safe and practical alternative to methyl isocyanate for carbamoylation reactions. We have developed a new chemical route for its synthesis from methyl iodide and applied this to the synthesis of N-[11C]methyl carbamoylimidazole as a new [11C]synthon to radiolabel biomolecules for PET imaging research. N-[11C]methyl carbamoylimidazole was prepared from [11C]methyl iodide in 70–74% radiochemical yield (decay corrected) and can be used in situ for further reaction without purification. The reactivity of N-[11C]methyl carbamoylimidazole was demonstrated in a series of [11C]carbamoylation reactions." @default.
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• W2808941133 date "2018-06-19" @default.
• W2808941133 modified "2023-09-27" @default.
• W2808941133 title "Radiosynthesis and reactivity of N-[11C]methyl carbamoylimidazole" @default.
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• W2808941133 doi "https://doi.org/10.1007/s10967-018-5948-4" @default.
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