Matches in SemOpenAlex for { <https://semopenalex.org/work/W2808970771> ?p ?o ?g. }
- W2808970771 endingPage "486" @default.
- W2808970771 startingPage "464" @default.
- W2808970771 abstract "Lung cancer accounts for the greatest number of cancer deaths in the world. Tobacco smoke-associated cancers constitute the majority of lung cancer cases but never-smoker cancers comprise a significant and increasing fraction of cases. Recent genomic and transcriptomic sequencing efforts of lung cancers have revealed distinct sets of genetic aberrations of smoker and never-smoker lung cancers that implicate disparate biology and therapeutic strategies. Autochthonous mouse models have contributed greatly to our understanding of lung cancer biology and identified novel therapeutic targets and strategies in the era of targeted therapy. With the emergence of immuno-oncology, mouse models may continue to serve as valuable platforms for novel biological insights and therapeutic strategies. Here, we will review the variety of available autochthonous mouse models of lung cancer, their relation to human smoker and never-smoker lung cancers, and their application to immuno-oncology and immune checkpoint blockade that is revolutionizing lung cancer therapy." @default.
- W2808970771 created "2018-06-29" @default.
- W2808970771 creator A5012107830 @default.
- W2808970771 creator A5058854705 @default.
- W2808970771 date "2018-08-01" @default.
- W2808970771 modified "2023-10-16" @default.
- W2808970771 title "Autochthonous murine models for the study of smoker and never-smoker associated lung cancers" @default.
- W2808970771 cites W1499070585 @default.
- W2808970771 cites W1611210979 @default.
- W2808970771 cites W1675596428 @default.
- W2808970771 cites W1758507682 @default.
- W2808970771 cites W1822606535 @default.
- W2808970771 cites W1903523058 @default.
- W2808970771 cites W1908940658 @default.
- W2808970771 cites W1923410233 @default.
- W2808970771 cites W1959475468 @default.
- W2808970771 cites W1969292035 @default.
- W2808970771 cites W1972759536 @default.
- W2808970771 cites W1972906160 @default.
- W2808970771 cites W1974608253 @default.
- W2808970771 cites W1978286483 @default.
- W2808970771 cites W1980497534 @default.
- W2808970771 cites W1982488143 @default.
- W2808970771 cites W1982585264 @default.
- W2808970771 cites W1984328451 @default.
- W2808970771 cites W1986815428 @default.
- W2808970771 cites W1988914246 @default.
- W2808970771 cites W1990626198 @default.
- W2808970771 cites W1991761652 @default.
- W2808970771 cites W1991874467 @default.
- W2808970771 cites W1992280840 @default.
- W2808970771 cites W1994772304 @default.
- W2808970771 cites W1996563138 @default.
- W2808970771 cites W1996666174 @default.
- W2808970771 cites W1997476230 @default.
- W2808970771 cites W1999462166 @default.
- W2808970771 cites W2000954296 @default.
- W2808970771 cites W2001999652 @default.
- W2808970771 cites W2005029697 @default.
- W2808970771 cites W2007649418 @default.
- W2808970771 cites W2008437931 @default.
- W2808970771 cites W2009093100 @default.
- W2808970771 cites W2010685617 @default.
- W2808970771 cites W2015137322 @default.
- W2808970771 cites W2020308175 @default.
- W2808970771 cites W2020830322 @default.
- W2808970771 cites W2021276286 @default.
- W2808970771 cites W2021312892 @default.
- W2808970771 cites W2021876472 @default.
- W2808970771 cites W2021983131 @default.
- W2808970771 cites W2023171799 @default.
- W2808970771 cites W2023975001 @default.
- W2808970771 cites W2024722383 @default.
- W2808970771 cites W2026115971 @default.
- W2808970771 cites W2029764427 @default.
- W2808970771 cites W2029949793 @default.
- W2808970771 cites W2032019019 @default.
- W2808970771 cites W2033513162 @default.
- W2808970771 cites W2035362119 @default.
- W2808970771 cites W2038586807 @default.
- W2808970771 cites W2041217592 @default.
- W2808970771 cites W2041992600 @default.
- W2808970771 cites W2043696829 @default.
- W2808970771 cites W2044936103 @default.
- W2808970771 cites W2044943027 @default.
- W2808970771 cites W2045729702 @default.
- W2808970771 cites W2048649566 @default.
- W2808970771 cites W2049553585 @default.
- W2808970771 cites W2053242489 @default.
- W2808970771 cites W2053627244 @default.
- W2808970771 cites W2053736534 @default.
- W2808970771 cites W2054607545 @default.
- W2808970771 cites W2054901736 @default.
- W2808970771 cites W2055402151 @default.
- W2808970771 cites W2057036781 @default.
- W2808970771 cites W2057701529 @default.
- W2808970771 cites W2058596850 @default.
- W2808970771 cites W2060688738 @default.
- W2808970771 cites W2063043104 @default.
- W2808970771 cites W2065799563 @default.
- W2808970771 cites W2066417528 @default.
- W2808970771 cites W2066671159 @default.
- W2808970771 cites W2069534609 @default.
- W2808970771 cites W2070011883 @default.
- W2808970771 cites W2070611230 @default.
- W2808970771 cites W2070963752 @default.
- W2808970771 cites W2072165205 @default.
- W2808970771 cites W2076356973 @default.
- W2808970771 cites W2077297619 @default.
- W2808970771 cites W2080992857 @default.
- W2808970771 cites W2081069851 @default.
- W2808970771 cites W2081801534 @default.
- W2808970771 cites W2081990599 @default.
- W2808970771 cites W2091070104 @default.
- W2808970771 cites W2091223735 @default.
- W2808970771 cites W2091540336 @default.
- W2808970771 cites W2096156234 @default.
- W2808970771 cites W2099035230 @default.