FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809040176> ?p ?o ?g. }

• W2809040176 abstract "INTRODUCTION :Lung cancer is a major health problem worldwide. The incidence isincreasing globally at a rate of 0.5% per year. It is the leading cause of cancermortality in most of the countries in the world. It remains the most lethal form ofcancer in men and has now surpassed breast cancer in women as well in USA,where 170,000 new cases are diagnosed per year. But in India Lung cancer issecond only to breast cancer in females. The worldwide incidence is 14%whereas it constitutes 6.8% of all carcinomas in India. The increase whether dueto the actual increase or due to the improvement in diagnostic techniques needsto be clarified? Complex circumstances like genetic predisposition, environmentalexposure, life style habits combine over a lifetime to initiate and promote tumorgrowth in the lung. Despite advances in imaging techniques and treatmentmodalities, the prognosis of lung cancer remains poor, with a five-year survival of14% in early stages and less than 5% in locally advanced stages. Unfortunatelyonly 20-30% of patients present with an operable disease, while most of thepatients present in an advanced stage III and IV. The main reason for late presentation in our country is the poor health awareness, delayed recognition and the poor referral of patients to the specialized centers.AIM OF THE STUDY :To study the Clinicopathological, Radiological profile, possible associated risk factors and diagnostic modalities of Primary Lung Cancer in females.DESIGN OF THE STUDY : Prospective.This study was examined and approved by the Ethical Committee of the Institution.MATERIALS AND METHODS :An open prospective study of female patients who attended Thoracic Medicine Department of Government General Hospital Chennai and Institute of Thoracic Medicine, Chetpet with Clinical and Radiological features suspicious of Primary Lung Cancer were studied over a period of 15 months between June 2006 and August 2007.The study protocol included a detailed history regarding the onset and progress of the disease, lifetime exposure to smoking, detailed occupational history, residence and exposure to indoor air pollution due to burning of organic fuels. A detailed history regarding malignancy in the first degree relatives of patients was also taken. Female patients with a clinical assessment suggestive of primary lung cancer and proven histology only were included in this study.Total numbers of female Patients diagnosed to have Primary lung cancer were compared with the total numbers of male Patients with Primary Lung cancer diagnosed during the same period to detect the Sex ratio.The complaints which were evaluated in detail included Cough, Sputum, hemoptysis, chest pain, dyspnoea, fever, weight loss, hoarseness of voice, dysphagia and symptoms suggestive of SVC obstruction, para neoplastic syndromes and systemic metastasis. A detailed general and systemic examination was performed.All patients were subjected to baseline blood investigations, sputum for AFB smear and culture, sputum for non tuberculous culture, sputum for cytology, chest X-ray PA view and corresponding lateral view, ultrasound chest and abdomen. Computerized Tomography of the chest and upper abdomen was done to characterize the lesion further, to help to arrive at tissue diagnosis and to stage the disease. FOB was performed in all patients who were fit for the procedure. Computerized Tomography of brain and bone scan was done if indicated.RESULTS :31 patients were included in the study. Pathological diagnosis was possible in 30 patients. Cell type diagnosis was not possible in one patient.However clinical and X-ray features suggestive of Primary Lung cancer and that was confirmed by presence of Malignant cells in pleural fluid and ultrasonography guided needle biopsy specimen.CONCLUSIONS :• There is definitely a increasing trend in the incidence of Primary Lung Cancer in females when compared with the previous studies conducted in our institution. This disturbing trend inline with global situation needs further evaluation.• Maximum number of patients was between 41-50 years of age.• Environmental Tobacco Smoke and Bio-mass cooking fuelexposure constituted about 84 % of Risk Factors identified in this study.• In addition to the above risk factors, occupational pollutants / Radiation have an additive effect in the background of Genetic predisposition in the causation of Lung Cancer in females.• Most common Pathological cell type in females was AdenoCarcinoma.• Most common Radiological presentation was Mass lesion followed by pleural effusion.• 83 % of patients were in the advanced stage of disease at the time of presentation.• Fibreoptic bronchoscope Biopsy and Brushing / ComputerizedTomography / Ultrasound guided core needle Biopsy were valuable tools to get a tissue diagnosis.• Lung lesions in females in high risk age group of 40 years and above should be investigated without gender bias thoroughly to rule out malignancy. This approach may result in diagnosing malignancy at an early stage. Primary Lung malignancies are common only in smokers, is proved as a misconception as evidenced by this study." @default.
• W2809040176 created "2018-06-29" @default.
• W2809040176 creator A5007583774 @default.
• W2809040176 date "2008-03-01" @default.
• W2809040176 modified "2023-09-24" @default.
• W2809040176 title "Primary Lung Cancer in Females: A Descriptive Study" @default.
• W2809040176 hasPublicationYear "2008" @default.
• W2809040176 type Work @default.
• W2809040176 sameAs 2809040176 @default.
• W2809040176 citedByCount "0" @default.
• W2809040176 crossrefType "dissertation" @default.
• W2809040176 hasAuthorship W2809040176A5007583774 @default.
• W2809040176 hasConcept C120665830 @default.
• W2809040176 hasConcept C121332964 @default.
• W2809040176 hasConcept C121608353 @default.
• W2809040176 hasConcept C126322002 @default.
• W2809040176 hasConcept C143998085 @default.
• W2809040176 hasConcept C146357865 @default.
• W2809040176 hasConcept C151730666 @default.
• W2809040176 hasConcept C2776135927 @default.
• W2809040176 hasConcept C2776256026 @default.
• W2809040176 hasConcept C2779134260 @default.
• W2809040176 hasConcept C512399662 @default.
• W2809040176 hasConcept C530470458 @default.
• W2809040176 hasConcept C61511704 @default.
• W2809040176 hasConcept C67636389 @default.
• W2809040176 hasConcept C71924100 @default.
• W2809040176 hasConcept C86803240 @default.
• W2809040176 hasConceptScore W2809040176C120665830 @default.
• W2809040176 hasConceptScore W2809040176C121332964 @default.
• W2809040176 hasConceptScore W2809040176C121608353 @default.
• W2809040176 hasConceptScore W2809040176C126322002 @default.
• W2809040176 hasConceptScore W2809040176C143998085 @default.
• W2809040176 hasConceptScore W2809040176C146357865 @default.
• W2809040176 hasConceptScore W2809040176C151730666 @default.
• W2809040176 hasConceptScore W2809040176C2776135927 @default.
• W2809040176 hasConceptScore W2809040176C2776256026 @default.
• W2809040176 hasConceptScore W2809040176C2779134260 @default.
• W2809040176 hasConceptScore W2809040176C512399662 @default.
• W2809040176 hasConceptScore W2809040176C530470458 @default.
• W2809040176 hasConceptScore W2809040176C61511704 @default.
• W2809040176 hasConceptScore W2809040176C67636389 @default.
• W2809040176 hasConceptScore W2809040176C71924100 @default.
• W2809040176 hasConceptScore W2809040176C86803240 @default.
• W2809040176 hasLocation W28090401761 @default.
• W2809040176 hasOpenAccess W2809040176 @default.
• W2809040176 hasPrimaryLocation W28090401761 @default.
• W2809040176 hasRelatedWork W1884185949 @default.
• W2809040176 hasRelatedWork W2035179583 @default.
• W2809040176 hasRelatedWork W2119488607 @default.
• W2809040176 hasRelatedWork W2136332371 @default.
• W2809040176 hasRelatedWork W2332949917 @default.
• W2809040176 hasRelatedWork W2353125093 @default.
• W2809040176 hasRelatedWork W2373114240 @default.
• W2809040176 hasRelatedWork W2387505323 @default.
• W2809040176 hasRelatedWork W2461038592 @default.
• W2809040176 hasRelatedWork W2735121932 @default.
• W2809040176 hasRelatedWork W2746529579 @default.
• W2809040176 hasRelatedWork W2810080850 @default.
• W2809040176 hasRelatedWork W2943705431 @default.
• W2809040176 hasRelatedWork W2951495239 @default.
• W2809040176 hasRelatedWork W2967679861 @default.
• W2809040176 hasRelatedWork W2968947516 @default.
• W2809040176 hasRelatedWork W3129762211 @default.
• W2809040176 hasRelatedWork W3134808990 @default.
• W2809040176 hasRelatedWork W95631680 @default.
• W2809040176 hasRelatedWork W2149520170 @default.
• W2809040176 isParatext "false" @default.
• W2809040176 isRetracted "false" @default.
• W2809040176 magId "2809040176" @default.
• W2809040176 workType "dissertation" @default.