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- W2809059905 abstract "Abstract Ulcerative colitis is a disease mainly characterized by chronic inflammation and an increased production of pro inflammatory cytokines and reactive oxygen species, which are frequently associated with zinc (Zn) deficiency. Zn supplementation can be beneficial to the treatment of ulcerative colitis, because of the anti-inflammatory and antioxidant properties of Zn. A blind intervention study involving 41 patients diagnosed with ulcerative colitis, aimed at evaluating the effect of Zn supplementation (35 mg Zn gluconate/day for 30 days) on the plasma and erythrocyte concentrations of Zn, the gene expression of metallothionein 1 G (MT1G) and ZIP-14, and the serum levels of TNF-α, IL-6, IL-10 was performed. Significant increases in the plasma and erythrocyte concentrations of Zn were observed after Zn supplementation (p" @default.
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- W2809059905 date "2018-09-01" @default.
- W2809059905 modified "2023-10-03" @default.
- W2809059905 title "Zinc supplementation reduces inflammation in ulcerative colitis patients by downregulating gene expression of Zn metalloproteins" @default.
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- W2809059905 doi "https://doi.org/10.1016/j.phanu.2018.06.004" @default.
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