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• W2809133082 endingPage "977" @default.
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• W2809133082 abstract "Clinicians are increasingly challenged by patients with refractory vulvovaginal candidiasis (VVC) caused by azole-resistant Candida species. Fluconazole resistant C.albicans is a growing and perplexing problem following years of indiscriminate drug prescription and unnecessary drug exposure and for which there are few therapeutic alternatives. Regrettably, although the azole class of drugs has expanded, new classes of antifungal drugs have not been forthcoming, limiting effective treatment options in patients with azole resistant Candida vaginitis.This review covers published data on epidemiology, pathophysiology and treatment options for women with azole-resistant refractory VVC.Fluconazole resistant C.albicans adds to the challenge of azole resistant non-albicans Candida spp. Both issues follow years of indiscriminate drug prescription and unnecessary fluconazole exposure. Although an understanding of azole resistance in yeast has been established, this knowledge has not translated into useful therapeutic advantage. Treatment options for such women with refractory symptoms are extremely limited. New therapeutic options and strategies are urgently needed to meet this challenge of azole drug resistance." @default.
• W2809133082 created "2018-06-29" @default.
• W2809133082 creator A5034076838 @default.
• W2809133082 creator A5054286469 @default.
• W2809133082 date "2018-06-13" @default.
• W2809133082 modified "2023-10-05" @default.
• W2809133082 title "Current treatment options for vulvovaginal candidiasis caused by azole-resistant Candida species" @default.
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• W2809133082 doi "https://doi.org/10.1080/14656566.2018.1476490" @default.
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• W2809133082 hasPublicationYear "2018" @default.
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