FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809199083> ?p ?o ?g. }

• W2809199083 abstract "BACKGROUND Induction immunosuppression is used in transplantation to prevent early acute rejection. The survival benefit of rabbit anti-thymocyte globulin (rATG) induction has not been established yet. We sought to determine the role of rATG in preventing rejection and improving overall survival. MATERIAL AND METHODS A retrospective cohort study was conducted from 2005 to 2009 and data of consecutive 268 heart transplant recipients were reviewed. RESULTS The data of 144 patients who received induction with rATG were compared to 124 patients who did not. Although overall survival was not different between the 2 groups (P=0.12), there was a significant difference in restricted mean survival time (RMST) at 5 years (RMST=4.8 months; 95% CI: 1.0-8.6, P=0.01) and 10 years (RMST=10.4 months; 95% CI: 1.6-19.3, P=0.02) in favor of the non-induced patients. No difference was observed between induced and non-induced patients who developed de novo donor specific antibodies. There was a significant difference in median days to first rejection in favor of the induced group (P<0.001). CONCLUSIONS Induction with rATG adds no survival benefit in heart transplant recipients. Patients who did not receive induction therapy had higher life expectancy at 5 years and 10 years. Although there was significant delay in the first rejection episode in favor of the rATG induced group, no difference was observed in donor specific antibodies. This study indicates a need for separate analysis of peri-transplantation co-morbidities and mainly the incidence of acute kidney injury, which could affect long-term survival." @default.
• W2809199083 created "2018-06-29" @default.
• W2809199083 creator A5001872995 @default.
• W2809199083 creator A5007739878 @default.
• W2809199083 creator A5010579236 @default.
• W2809199083 creator A5019680774 @default.
• W2809199083 creator A5051755752 @default.
• W2809199083 creator A5066293663 @default.
• W2809199083 creator A5073611097 @default.
• W2809199083 creator A5076659442 @default.
• W2809199083 date "2018-06-19" @default.
• W2809199083 modified "2023-09-25" @default.
• W2809199083 title "Outcomes of Induction Therapy with Rabbit Anti-Thymocyte Globulin in Heart Transplant Recipients: A Single Center Retrospective Cohort Study" @default.
• W2809199083 cites W1528091973 @default.
• W2809199083 cites W1837638008 @default.
• W2809199083 cites W1939649145 @default.
• W2809199083 cites W1963898897 @default.
• W2809199083 cites W1966020049 @default.
• W2809199083 cites W1968898400 @default.
• W2809199083 cites W1976230377 @default.
• W2809199083 cites W1980998626 @default.
• W2809199083 cites W1987718789 @default.
• W2809199083 cites W2001455084 @default.
• W2809199083 cites W2008931717 @default.
• W2809199083 cites W2028208800 @default.
• W2809199083 cites W2060053600 @default.
• W2809199083 cites W2079830501 @default.
• W2809199083 cites W2091851863 @default.
• W2809199083 cites W2105086997 @default.
• W2809199083 cites W2110621091 @default.
• W2809199083 cites W2110716950 @default.
• W2809199083 cites W2110926406 @default.
• W2809199083 cites W2133842584 @default.
• W2809199083 cites W2135369095 @default.
• W2809199083 cites W2273497655 @default.
• W2809199083 cites W2341139192 @default.
• W2809199083 cites W2736605237 @default.
• W2809199083 cites W4253750716 @default.
• W2809199083 doi "https://doi.org/10.12659/aot.907984" @default.
• W2809199083 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6248055" @default.
• W2809199083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29915167" @default.
• W2809199083 hasPublicationYear "2018" @default.
• W2809199083 type Work @default.
• W2809199083 sameAs 2809199083 @default.
• W2809199083 citedByCount "4" @default.
• W2809199083 countsByYear W28091990832021 @default.
• W2809199083 countsByYear W28091990832022 @default.
• W2809199083 crossrefType "journal-article" @default.
• W2809199083 hasAuthorship W2809199083A5001872995 @default.
• W2809199083 hasAuthorship W2809199083A5007739878 @default.
• W2809199083 hasAuthorship W2809199083A5010579236 @default.
• W2809199083 hasAuthorship W2809199083A5019680774 @default.
• W2809199083 hasAuthorship W2809199083A5051755752 @default.
• W2809199083 hasAuthorship W2809199083A5066293663 @default.
• W2809199083 hasAuthorship W2809199083A5073611097 @default.
• W2809199083 hasAuthorship W2809199083A5076659442 @default.
• W2809199083 hasBestOaLocation W28091990832 @default.
• W2809199083 hasConcept C120665830 @default.
• W2809199083 hasConcept C121332964 @default.
• W2809199083 hasConcept C126322002 @default.
• W2809199083 hasConcept C141071460 @default.
• W2809199083 hasConcept C167135981 @default.
• W2809199083 hasConcept C2776694085 @default.
• W2809199083 hasConcept C2778849806 @default.
• W2809199083 hasConcept C2780073493 @default.
• W2809199083 hasConcept C2780252810 @default.
• W2809199083 hasConcept C2780882860 @default.
• W2809199083 hasConcept C2911091166 @default.
• W2809199083 hasConcept C2991767035 @default.
• W2809199083 hasConcept C61511704 @default.
• W2809199083 hasConcept C71924100 @default.
• W2809199083 hasConcept C72563966 @default.
• W2809199083 hasConceptScore W2809199083C120665830 @default.
• W2809199083 hasConceptScore W2809199083C121332964 @default.
• W2809199083 hasConceptScore W2809199083C126322002 @default.
• W2809199083 hasConceptScore W2809199083C141071460 @default.
• W2809199083 hasConceptScore W2809199083C167135981 @default.
• W2809199083 hasConceptScore W2809199083C2776694085 @default.
• W2809199083 hasConceptScore W2809199083C2778849806 @default.
• W2809199083 hasConceptScore W2809199083C2780073493 @default.
• W2809199083 hasConceptScore W2809199083C2780252810 @default.
• W2809199083 hasConceptScore W2809199083C2780882860 @default.
• W2809199083 hasConceptScore W2809199083C2911091166 @default.
• W2809199083 hasConceptScore W2809199083C2991767035 @default.
• W2809199083 hasConceptScore W2809199083C61511704 @default.
• W2809199083 hasConceptScore W2809199083C71924100 @default.
• W2809199083 hasConceptScore W2809199083C72563966 @default.
• W2809199083 hasLocation W28091990831 @default.
• W2809199083 hasLocation W28091990832 @default.
• W2809199083 hasLocation W28091990833 @default.
• W2809199083 hasLocation W28091990834 @default.
• W2809199083 hasOpenAccess W2809199083 @default.
• W2809199083 hasPrimaryLocation W28091990831 @default.
• W2809199083 hasRelatedWork W1968059227 @default.
• W2809199083 hasRelatedWork W1974414773 @default.
• W2809199083 hasRelatedWork W1990658516 @default.
• W2809199083 hasRelatedWork W2012742591 @default.
• W2809199083 hasRelatedWork W2023955780 @default.
• W2809199083 hasRelatedWork W2028001665 @default.
• W2809199083 hasRelatedWork W2058888252 @default.

• next