FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809201572> ?p ?o ?g. }

• W2809201572 endingPage "284" @default.
• W2809201572 startingPage "275" @default.
• W2809201572 abstract "Polycystic ovary syndrome (PCOS) is a common form of the endocrine disease which is associated with metabolic dysfunction. PCOS and type 2 diabetes mellitus are related in multiple aspects and are similar in many pathological features. Anti-diabetic effects of Nigella sativa and protective effects of it on reproductive system have been suggested in some reports.The aim of current study was to evaluate the effects of thymoquinone, the main components of Nigella sativa, on PCOS model of rats.Intraperitoneal injection of estradiol valerate for 25 days was used to induce PCOS in Wistar rats, followed by intraperitoneal administration of 8 and 16 mg/kg thymoquinone for 30 days. Rats were divided into 5 groups; control, sham or PCOS, experiment-1 (PCOS and 8 mg/kg thymoquinone), experiment-2 (PCOS and 16 mg/kg thymoquinone), and metformin (PCOS and metformin administration, 100 mg/kg) groups. All of the animals were subjected to serum biochemical analysis of blood and histopathological study of ovaries.Estradiol valerate induced PCOS while administration of thymoquinone recovered it. The body weight, ovarian morphology, and ovulation had been improved and the serum biochemical parameters including glucose, triglyceride, total cholesterol, low-density lipoprotein, high-density lipoprotein, luteinizing hormone, and follicle stimulating hormone were reversed after thymoquinone intervention.Our data suggest that thymoquinone has improvement effects on an ovarian function and ovulation in the PCOS rat model. Therefore, thymoquinone and Nagilla sativa could be used as a protective agent and as an adjunct treatment in PCOS patients." @default.
• W2809201572 created "2018-06-29" @default.
• W2809201572 creator A5002170628 @default.
• W2809201572 creator A5074323973 @default.
• W2809201572 creator A5088492195 @default.
• W2809201572 date "2018-04-01" @default.
• W2809201572 modified "2023-10-10" @default.
• W2809201572 title "Thymoquinone ameliorates some endocrine parameters and histological alteration in a rat model of polycystic ovary syndrome" @default.
• W2809201572 cites W1595119963 @default.
• W2809201572 cites W1912874972 @default.
• W2809201572 cites W1968307867 @default.
• W2809201572 cites W1973764569 @default.
• W2809201572 cites W1985392344 @default.
• W2809201572 cites W1989006615 @default.
• W2809201572 cites W2006400809 @default.
• W2809201572 cites W2016903551 @default.
• W2809201572 cites W2017602185 @default.
• W2809201572 cites W2024521825 @default.
• W2809201572 cites W2032360183 @default.
• W2809201572 cites W2035026428 @default.
• W2809201572 cites W2067831929 @default.
• W2809201572 cites W2080367283 @default.
• W2809201572 cites W2096929808 @default.
• W2809201572 cites W2114720475 @default.
• W2809201572 cites W2114726424 @default.
• W2809201572 cites W2116245445 @default.
• W2809201572 cites W2116404316 @default.
• W2809201572 cites W2122764986 @default.
• W2809201572 cites W2126700142 @default.
• W2809201572 cites W2138939427 @default.
• W2809201572 cites W2144883605 @default.
• W2809201572 cites W2147127250 @default.
• W2809201572 cites W2155715955 @default.
• W2809201572 cites W2166153413 @default.
• W2809201572 cites W2170146596 @default.
• W2809201572 cites W2218787476 @default.
• W2809201572 cites W2294158852 @default.
• W2809201572 cites W2335179308 @default.
• W2809201572 cites W2340898396 @default.
• W2809201572 cites W2908924382 @default.
• W2809201572 doi "https://doi.org/10.29252/ijrm.16.4.275" @default.
• W2809201572 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6004595" @default.
• W2809201572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29942936" @default.
• W2809201572 hasPublicationYear "2018" @default.
• W2809201572 type Work @default.
• W2809201572 sameAs 2809201572 @default.
• W2809201572 citedByCount "8" @default.
• W2809201572 countsByYear W28092015722019 @default.
• W2809201572 countsByYear W28092015722021 @default.
• W2809201572 countsByYear W28092015722022 @default.
• W2809201572 countsByYear W28092015722023 @default.
• W2809201572 crossrefType "journal-article" @default.
• W2809201572 hasAuthorship W2809201572A5002170628 @default.
• W2809201572 hasAuthorship W2809201572A5074323973 @default.
• W2809201572 hasAuthorship W2809201572A5088492195 @default.
• W2809201572 hasBestOaLocation W28092015721 @default.
• W2809201572 hasConcept C126322002 @default.
• W2809201572 hasConcept C134018914 @default.
• W2809201572 hasConcept C2777391703 @default.
• W2809201572 hasConcept C2777702977 @default.
• W2809201572 hasConcept C2778001906 @default.
• W2809201572 hasConcept C2778004101 @default.
• W2809201572 hasConcept C2779034068 @default.
• W2809201572 hasConcept C2780323712 @default.
• W2809201572 hasConcept C2993714443 @default.
• W2809201572 hasConcept C3018442814 @default.
• W2809201572 hasConcept C46699223 @default.
• W2809201572 hasConcept C55493867 @default.
• W2809201572 hasConcept C555293320 @default.
• W2809201572 hasConcept C556039675 @default.
• W2809201572 hasConcept C71315377 @default.
• W2809201572 hasConcept C71924100 @default.
• W2809201572 hasConcept C86803240 @default.
• W2809201572 hasConceptScore W2809201572C126322002 @default.
• W2809201572 hasConceptScore W2809201572C134018914 @default.
• W2809201572 hasConceptScore W2809201572C2777391703 @default.
• W2809201572 hasConceptScore W2809201572C2777702977 @default.
• W2809201572 hasConceptScore W2809201572C2778001906 @default.
• W2809201572 hasConceptScore W2809201572C2778004101 @default.
• W2809201572 hasConceptScore W2809201572C2779034068 @default.
• W2809201572 hasConceptScore W2809201572C2780323712 @default.
• W2809201572 hasConceptScore W2809201572C2993714443 @default.
• W2809201572 hasConceptScore W2809201572C3018442814 @default.
• W2809201572 hasConceptScore W2809201572C46699223 @default.
• W2809201572 hasConceptScore W2809201572C55493867 @default.
• W2809201572 hasConceptScore W2809201572C555293320 @default.
• W2809201572 hasConceptScore W2809201572C556039675 @default.
• W2809201572 hasConceptScore W2809201572C71315377 @default.
• W2809201572 hasConceptScore W2809201572C71924100 @default.
• W2809201572 hasConceptScore W2809201572C86803240 @default.
• W2809201572 hasIssue "4" @default.
• W2809201572 hasLocation W28092015721 @default.
• W2809201572 hasLocation W28092015722 @default.
• W2809201572 hasLocation W28092015723 @default.
• W2809201572 hasOpenAccess W2809201572 @default.
• W2809201572 hasPrimaryLocation W28092015721 @default.
• W2809201572 hasRelatedWork W1835582227 @default.
• W2809201572 hasRelatedWork W1986311037 @default.

• next