FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809262999> ?p ?o ?g. }

• W2809262999 abstract "β-hydroxy β-methylbutyrate (HMB) is a nutritional supplement purported to enhance skeletal muscle mass and strength, as well as cognitive function in older adults. The purpose of this study was to determine the potential for long-term HMB supplementation to preserve muscle function and cognition in aged mice, as well as provide evidence of a link between vessel-associated pericyte function and outcomes. Four- (Adult/Ad) and 17 month-old (Aged/Ag) C57BL/6J mice consumed chow containing 600 mg/kg BW/day of either Ca-HMB (Ad, n=16; Ag, n=17) or Ca-Lactate (Ad, n=16; Ag, n=17) for 6 months. HMB did not prevent age-related reductions in muscle mass, strength and coordination (Age main effect, P<0.05). The rate of muscle protein synthesis decreased within the mitochondrial fraction (age main effect, P<0.05), and this decline was not prevented with HMB. Despite no change in muscle mass or function, an age-dependent reduction in active avoidance learning was attenuated with HMB (Age and HMB main effects, P<0.05). Age detrimentally impacted muscle-resident pericyte gene expression with no recovery observed with HMB, whereas no changes in brain-resident pericyte quantity or function were observed with age or HMB. The findings from this study suggest that prolonged HMB supplementation starting in adulthood may preserve cognition with age." @default.
• W2809262999 created "2018-06-29" @default.
• W2809262999 creator A5005053777 @default.
• W2809262999 creator A5014660760 @default.
• W2809262999 creator A5028251070 @default.
• W2809262999 creator A5051614460 @default.
• W2809262999 creator A5053942773 @default.
• W2809262999 creator A5066810306 @default.
• W2809262999 creator A5078520807 @default.
• W2809262999 creator A5080415757 @default.
• W2809262999 date "2018-06-19" @default.
• W2809262999 modified "2023-10-12" @default.
• W2809262999 title "Cognitive function is preserved in aged mice following long-term β-hydroxy β-methylbutyrate supplementation" @default.
• W2809262999 cites W1206885699 @default.
• W2809262999 cites W1500093205 @default.
• W2809262999 cites W1567524252 @default.
• W2809262999 cites W1845134197 @default.
• W2809262999 cites W1921383166 @default.
• W2809262999 cites W1936102533 @default.
• W2809262999 cites W1971117721 @default.
• W2809262999 cites W1977836459 @default.
• W2809262999 cites W1992837786 @default.
• W2809262999 cites W1995313036 @default.
• W2809262999 cites W2000532682 @default.
• W2809262999 cites W2001417852 @default.
• W2809262999 cites W2001552996 @default.
• W2809262999 cites W2008765449 @default.
• W2809262999 cites W2012953364 @default.
• W2809262999 cites W2014510851 @default.
• W2809262999 cites W2018258390 @default.
• W2809262999 cites W2022774730 @default.
• W2809262999 cites W2025248274 @default.
• W2809262999 cites W2031401291 @default.
• W2809262999 cites W2038500045 @default.
• W2809262999 cites W2055917728 @default.
• W2809262999 cites W2058661925 @default.
• W2809262999 cites W2075623307 @default.
• W2809262999 cites W2076491580 @default.
• W2809262999 cites W2085100642 @default.
• W2809262999 cites W2085261244 @default.
• W2809262999 cites W2088467209 @default.
• W2809262999 cites W2104144179 @default.
• W2809262999 cites W2109290881 @default.
• W2809262999 cites W2110839189 @default.
• W2809262999 cites W2111318336 @default.
• W2809262999 cites W2115390024 @default.
• W2809262999 cites W2116618309 @default.
• W2809262999 cites W2116789485 @default.
• W2809262999 cites W2129894754 @default.
• W2809262999 cites W2131554627 @default.
• W2809262999 cites W2134707918 @default.
• W2809262999 cites W2149476081 @default.
• W2809262999 cites W2163179762 @default.
• W2809262999 cites W2164372979 @default.
• W2809262999 cites W2167013734 @default.
• W2809262999 cites W2281081766 @default.
• W2809262999 cites W2294537652 @default.
• W2809262999 cites W2345991195 @default.
• W2809262999 cites W2427154682 @default.
• W2809262999 cites W2429359053 @default.
• W2809262999 cites W2552206114 @default.
• W2809262999 cites W2566158792 @default.
• W2809262999 cites W2612068365 @default.
• W2809262999 cites W2735380801 @default.
• W2809262999 cites W43396469 @default.
• W2809262999 doi "https://doi.org/10.1080/1028415x.2018.1483101" @default.
• W2809262999 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29914347" @default.
• W2809262999 hasPublicationYear "2018" @default.
• W2809262999 type Work @default.
• W2809262999 sameAs 2809262999 @default.
• W2809262999 citedByCount "4" @default.
• W2809262999 countsByYear W28092629992019 @default.
• W2809262999 countsByYear W28092629992020 @default.
• W2809262999 countsByYear W28092629992021 @default.
• W2809262999 crossrefType "journal-article" @default.
• W2809262999 hasAuthorship W2809262999A5005053777 @default.
• W2809262999 hasAuthorship W2809262999A5014660760 @default.
• W2809262999 hasAuthorship W2809262999A5028251070 @default.
• W2809262999 hasAuthorship W2809262999A5051614460 @default.
• W2809262999 hasAuthorship W2809262999A5053942773 @default.
• W2809262999 hasAuthorship W2809262999A5066810306 @default.
• W2809262999 hasAuthorship W2809262999A5078520807 @default.
• W2809262999 hasAuthorship W2809262999A5080415757 @default.
• W2809262999 hasConcept C126322002 @default.
• W2809262999 hasConcept C134018914 @default.
• W2809262999 hasConcept C2776214593 @default.
• W2809262999 hasConcept C2779134260 @default.
• W2809262999 hasConcept C2779483572 @default.
• W2809262999 hasConcept C2779959927 @default.
• W2809262999 hasConcept C2984863031 @default.
• W2809262999 hasConcept C71924100 @default.
• W2809262999 hasConcept C86803240 @default.
• W2809262999 hasConceptScore W2809262999C126322002 @default.
• W2809262999 hasConceptScore W2809262999C134018914 @default.
• W2809262999 hasConceptScore W2809262999C2776214593 @default.
• W2809262999 hasConceptScore W2809262999C2779134260 @default.
• W2809262999 hasConceptScore W2809262999C2779483572 @default.
• W2809262999 hasConceptScore W2809262999C2779959927 @default.
• W2809262999 hasConceptScore W2809262999C2984863031 @default.
• W2809262999 hasConceptScore W2809262999C71924100 @default.

• next