FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809301672> ?p ?o ?g. }

• W2809301672 abstract "Liver receptor homologue 1 (LRH-1) is an orphan nuclear receptor that is highly expressed in a variety of cancer tissues, promotes tumor cell proliferation and metastasis, and is involved in the tumor cell cycle and apoptosis. The aim of the present study was to assess the association between the expression of LRH-1 and the prognosis of patients with colon cancer. Immunohistochemistry was used to detect the expression of LRH1 in 128 cases of colon cancer and adjacent tissues. The 5-year survival rate was obtained from telephone follow-up data, outpatient review and through access to medical records. Positive expression of LRH-1 was found in 108/128 colon cancer samples, compared with 17/128 normal tissues. Statistical analysis showed that positive LRH-1 expression was significantly associated with clinical pathological stage, depth of invasion and lymph node metastasis. The overall survival (OS) rate of patients with positive LRH-1 expression was significantly lower than that of patients with low expression. Multivariate analysis showed that LRH-1 expression could be used as an independent predictor of OS. In conclusion, the present findings suggest that LRH-1 may serve an important role in the development and progression of colon cancer, with potential value as a prognostic molecular marker that could be used to assist in the diagnosis and evaluation of colon cancer. LRH-1 may become a target for novel therapies for patients with colon cancer." @default.
• W2809301672 created "2018-06-29" @default.
• W2809301672 creator A5013273035 @default.
• W2809301672 creator A5018166874 @default.
• W2809301672 creator A5031987022 @default.
• W2809301672 creator A5033009742 @default.
• W2809301672 creator A5037237721 @default.
• W2809301672 creator A5049751624 @default.
• W2809301672 creator A5049761910 @default.
• W2809301672 creator A5072861069 @default.
• W2809301672 date "2018-06-18" @default.
• W2809301672 modified "2023-09-29" @default.
• W2809301672 title "Liver receptor homologue 1, a novel prognostic marker in colon cancer patients" @default.
• W2809301672 cites W1418748993 @default.
• W2809301672 cites W1820813862 @default.
• W2809301672 cites W1979259479 @default.
• W2809301672 cites W1981728847 @default.
• W2809301672 cites W1995887305 @default.
• W2809301672 cites W2003822865 @default.
• W2809301672 cites W2007795192 @default.
• W2809301672 cites W2009639026 @default.
• W2809301672 cites W2011571454 @default.
• W2809301672 cites W2017287612 @default.
• W2809301672 cites W2045519188 @default.
• W2809301672 cites W2057166785 @default.
• W2809301672 cites W2066161362 @default.
• W2809301672 cites W2074189826 @default.
• W2809301672 cites W2102800327 @default.
• W2809301672 cites W2111684219 @default.
• W2809301672 cites W2145431540 @default.
• W2809301672 cites W2287411540 @default.
• W2809301672 cites W2412387072 @default.
• W2809301672 cites W2474665195 @default.
• W2809301672 cites W2504954641 @default.
• W2809301672 doi "https://doi.org/10.3892/ol.2018.8988" @default.
• W2809301672 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6096149" @default.
• W2809301672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30127869" @default.
• W2809301672 hasPublicationYear "2018" @default.
• W2809301672 type Work @default.
• W2809301672 sameAs 2809301672 @default.
• W2809301672 citedByCount "10" @default.
• W2809301672 countsByYear W28093016722019 @default.
• W2809301672 countsByYear W28093016722020 @default.
• W2809301672 countsByYear W28093016722021 @default.
• W2809301672 countsByYear W28093016722022 @default.
• W2809301672 crossrefType "journal-article" @default.
• W2809301672 hasAuthorship W2809301672A5013273035 @default.
• W2809301672 hasAuthorship W2809301672A5018166874 @default.
• W2809301672 hasAuthorship W2809301672A5031987022 @default.
• W2809301672 hasAuthorship W2809301672A5033009742 @default.
• W2809301672 hasAuthorship W2809301672A5037237721 @default.
• W2809301672 hasAuthorship W2809301672A5049751624 @default.
• W2809301672 hasAuthorship W2809301672A5049761910 @default.
• W2809301672 hasAuthorship W2809301672A5072861069 @default.
• W2809301672 hasBestOaLocation W28093016721 @default.
• W2809301672 hasConcept C121608353 @default.
• W2809301672 hasConcept C126322002 @default.
• W2809301672 hasConcept C142724271 @default.
• W2809301672 hasConcept C143998085 @default.
• W2809301672 hasConcept C204232928 @default.
• W2809301672 hasConcept C207886595 @default.
• W2809301672 hasConcept C2779013556 @default.
• W2809301672 hasConcept C2781018059 @default.
• W2809301672 hasConcept C29537977 @default.
• W2809301672 hasConcept C502942594 @default.
• W2809301672 hasConcept C526805850 @default.
• W2809301672 hasConcept C67082663 @default.
• W2809301672 hasConcept C71924100 @default.
• W2809301672 hasConceptScore W2809301672C121608353 @default.
• W2809301672 hasConceptScore W2809301672C126322002 @default.
• W2809301672 hasConceptScore W2809301672C142724271 @default.
• W2809301672 hasConceptScore W2809301672C143998085 @default.
• W2809301672 hasConceptScore W2809301672C204232928 @default.
• W2809301672 hasConceptScore W2809301672C207886595 @default.
• W2809301672 hasConceptScore W2809301672C2779013556 @default.
• W2809301672 hasConceptScore W2809301672C2781018059 @default.
• W2809301672 hasConceptScore W2809301672C29537977 @default.
• W2809301672 hasConceptScore W2809301672C502942594 @default.
• W2809301672 hasConceptScore W2809301672C526805850 @default.
• W2809301672 hasConceptScore W2809301672C67082663 @default.
• W2809301672 hasConceptScore W2809301672C71924100 @default.
• W2809301672 hasLocation W28093016721 @default.
• W2809301672 hasLocation W28093016722 @default.
• W2809301672 hasLocation W28093016723 @default.
• W2809301672 hasLocation W28093016724 @default.
• W2809301672 hasOpenAccess W2809301672 @default.
• W2809301672 hasPrimaryLocation W28093016721 @default.
• W2809301672 hasRelatedWork W2017009483 @default.
• W2809301672 hasRelatedWork W2064384290 @default.
• W2809301672 hasRelatedWork W2108827015 @default.
• W2809301672 hasRelatedWork W2772993264 @default.
• W2809301672 hasRelatedWork W2808572916 @default.
• W2809301672 hasRelatedWork W2885058918 @default.
• W2809301672 hasRelatedWork W2885514468 @default.
• W2809301672 hasRelatedWork W2896971802 @default.
• W2809301672 hasRelatedWork W2897293755 @default.
• W2809301672 hasRelatedWork W2906716748 @default.
• W2809301672 isParatext "false" @default.
• W2809301672 isRetracted "false" @default.
• W2809301672 magId "2809301672" @default.

• next