Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809353518> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2809353518 endingPage "180" @default.
- W2809353518 startingPage "180" @default.
- W2809353518 abstract "Introduction: Osteoarthritis (OA) is a degenerative joint disease and cause for functional disability. OA is characterized by the insidious onset of pain and limited range of movements. Piroxicam and naproxen are used in OA, rheumatoid arthritis, acute gouty arthritis, migraine, dysmenorrhea, and postoperative pain. The aim of this study was to compare the efficacy and safety of these drugs in patients with OA of the knee. Materials and Methods: This was a randomized, open-label, comparative, parallel group study conducted in patients with OA of knee joints. They received either oral piroxicam 20 mg or naproxen 500 mg twice daily for 6 weeks. The pain was assessed using Visual Analog Scale (VAS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores at baseline, 2nd, 4th, and 6th week. Patient satisfaction score (PSS) and quality of life were assessed at follow-up. Adverse effects were assessed using the World Health Organization causality scale. Descriptive and inferential statistics were used. Results: A total of 110 patients were recruited, 47 males and 63 females, 100 completed the study (51 in Group P and 49 in Group N). Both piroxicam and naproxen significantly reduced VAS and WOMAC scores at the 2nd, 4th, and 6th week (P = 0.001) compared to baseline, but this was not significant between the groups. PSS was significantly (P = 0.03) high at 4th and 6th week when compared to week 2 with both medications, but between the medications, it was insignificant (P = 0.10). The adverse effects such as epigastric discomfort, nausea, and vomiting were observed with both the drugs, but it was more with naproxen. Conclusion: Piroxicam was as effective as naproxen in relieving pain and improving the range of movements with less adverse effects." @default.
- W2809353518 created "2018-06-29" @default.
- W2809353518 creator A5025279791 @default.
- W2809353518 creator A5048982940 @default.
- W2809353518 creator A5057745571 @default.
- W2809353518 date "2018-01-01" @default.
- W2809353518 modified "2023-09-23" @default.
- W2809353518 title "A comparative study of efficacy and safety of piroxicam and naproxen in the management of pain in osteoarthritis of the knee" @default.
- W2809353518 cites W3023844385 @default.
- W2809353518 doi "https://doi.org/10.4103/jnsbm.jnsbm_154_17" @default.
- W2809353518 hasPublicationYear "2018" @default.
- W2809353518 type Work @default.
- W2809353518 sameAs 2809353518 @default.
- W2809353518 citedByCount "1" @default.
- W2809353518 countsByYear W28093535182020 @default.
- W2809353518 crossrefType "journal-article" @default.
- W2809353518 hasAuthorship W2809353518A5025279791 @default.
- W2809353518 hasAuthorship W2809353518A5048982940 @default.
- W2809353518 hasAuthorship W2809353518A5057745571 @default.
- W2809353518 hasConcept C142724271 @default.
- W2809353518 hasConcept C1862650 @default.
- W2809353518 hasConcept C204787440 @default.
- W2809353518 hasConcept C2776164576 @default.
- W2809353518 hasConcept C2778115740 @default.
- W2809353518 hasConcept C2778139025 @default.
- W2809353518 hasConcept C2983098980 @default.
- W2809353518 hasConcept C71924100 @default.
- W2809353518 hasConceptScore W2809353518C142724271 @default.
- W2809353518 hasConceptScore W2809353518C1862650 @default.
- W2809353518 hasConceptScore W2809353518C204787440 @default.
- W2809353518 hasConceptScore W2809353518C2776164576 @default.
- W2809353518 hasConceptScore W2809353518C2778115740 @default.
- W2809353518 hasConceptScore W2809353518C2778139025 @default.
- W2809353518 hasConceptScore W2809353518C2983098980 @default.
- W2809353518 hasConceptScore W2809353518C71924100 @default.
- W2809353518 hasIssue "2" @default.
- W2809353518 hasLocation W28093535181 @default.
- W2809353518 hasOpenAccess W2809353518 @default.
- W2809353518 hasPrimaryLocation W28093535181 @default.
- W2809353518 hasRelatedWork W1964077836 @default.
- W2809353518 hasRelatedWork W1969107784 @default.
- W2809353518 hasRelatedWork W1974128002 @default.
- W2809353518 hasRelatedWork W2128366611 @default.
- W2809353518 hasRelatedWork W2140691760 @default.
- W2809353518 hasRelatedWork W2151886127 @default.
- W2809353518 hasRelatedWork W2210363419 @default.
- W2809353518 hasRelatedWork W2409391605 @default.
- W2809353518 hasRelatedWork W2418623264 @default.
- W2809353518 hasRelatedWork W50782164 @default.
- W2809353518 hasVolume "9" @default.
- W2809353518 isParatext "false" @default.
- W2809353518 isRetracted "false" @default.
- W2809353518 magId "2809353518" @default.
- W2809353518 workType "article" @default.