Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809417568> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2809417568 endingPage "32" @default.
- W2809417568 startingPage "29" @default.
- W2809417568 abstract "Switching from immunotherapy to targeted therapy in metastasized melanoma can be complicated by a cytokine release syndrome (CRS). CRS is a serious complication, which is induced by high levels of circulating cytokines, associated with T-cell engagement and proliferation, and results in a constellation of symptoms with variable organ involvement. We report 2 patients with BRAF V600 mutant melanoma who were previously treated with anti-PD-1±anti-LAG-3 antibodies and were switched to BRAF/MEK-inhibitors because of progressive disease. Both cases depict the complexity of interactions occurring during sequential treatment with immune checkpoint inhibitors and kinase inhibitors. Early identification and management of CRS is crucial to decrease its toxicity and improve safety of further drugs to be given in a therapeutic ladder." @default.
- W2809417568 created "2018-06-29" @default.
- W2809417568 creator A5008364803 @default.
- W2809417568 creator A5010285479 @default.
- W2809417568 creator A5030193621 @default.
- W2809417568 creator A5048592345 @default.
- W2809417568 creator A5063311905 @default.
- W2809417568 creator A5063558634 @default.
- W2809417568 creator A5082278497 @default.
- W2809417568 creator A5089297467 @default.
- W2809417568 date "2019-01-01" @default.
- W2809417568 modified "2023-09-25" @default.
- W2809417568 title "Cytokine Release Syndrome During Sequential Treatment With Immune Checkpoint Inhibitors and Kinase Inhibitors for Metastatic Melanoma" @default.
- W2809417568 cites W1557490668 @default.
- W2809417568 cites W1978165371 @default.
- W2809417568 cites W2044433401 @default.
- W2809417568 cites W2066671159 @default.
- W2809417568 cites W2078831149 @default.
- W2809417568 cites W2082708772 @default.
- W2809417568 cites W2114903025 @default.
- W2809417568 cites W2139591061 @default.
- W2809417568 cites W2605233023 @default.
- W2809417568 cites W2767533179 @default.
- W2809417568 doi "https://doi.org/10.1097/cji.0000000000000236" @default.
- W2809417568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29939877" @default.
- W2809417568 hasPublicationYear "2019" @default.
- W2809417568 type Work @default.
- W2809417568 sameAs 2809417568 @default.
- W2809417568 citedByCount "37" @default.
- W2809417568 countsByYear W28094175682018 @default.
- W2809417568 countsByYear W28094175682019 @default.
- W2809417568 countsByYear W28094175682020 @default.
- W2809417568 countsByYear W28094175682021 @default.
- W2809417568 countsByYear W28094175682022 @default.
- W2809417568 countsByYear W28094175682023 @default.
- W2809417568 crossrefType "journal-article" @default.
- W2809417568 hasAuthorship W2809417568A5008364803 @default.
- W2809417568 hasAuthorship W2809417568A5010285479 @default.
- W2809417568 hasAuthorship W2809417568A5030193621 @default.
- W2809417568 hasAuthorship W2809417568A5048592345 @default.
- W2809417568 hasAuthorship W2809417568A5063311905 @default.
- W2809417568 hasAuthorship W2809417568A5063558634 @default.
- W2809417568 hasAuthorship W2809417568A5082278497 @default.
- W2809417568 hasAuthorship W2809417568A5089297467 @default.
- W2809417568 hasBestOaLocation W28094175682 @default.
- W2809417568 hasConcept C184235292 @default.
- W2809417568 hasConcept C203014093 @default.
- W2809417568 hasConcept C2777658100 @default.
- W2809417568 hasConcept C2777701055 @default.
- W2809417568 hasConcept C2778690821 @default.
- W2809417568 hasConcept C2780850621 @default.
- W2809417568 hasConcept C2994587330 @default.
- W2809417568 hasConcept C3875195 @default.
- W2809417568 hasConcept C502942594 @default.
- W2809417568 hasConcept C71924100 @default.
- W2809417568 hasConcept C86803240 @default.
- W2809417568 hasConcept C8891405 @default.
- W2809417568 hasConcept C95444343 @default.
- W2809417568 hasConceptScore W2809417568C184235292 @default.
- W2809417568 hasConceptScore W2809417568C203014093 @default.
- W2809417568 hasConceptScore W2809417568C2777658100 @default.
- W2809417568 hasConceptScore W2809417568C2777701055 @default.
- W2809417568 hasConceptScore W2809417568C2778690821 @default.
- W2809417568 hasConceptScore W2809417568C2780850621 @default.
- W2809417568 hasConceptScore W2809417568C2994587330 @default.
- W2809417568 hasConceptScore W2809417568C3875195 @default.
- W2809417568 hasConceptScore W2809417568C502942594 @default.
- W2809417568 hasConceptScore W2809417568C71924100 @default.
- W2809417568 hasConceptScore W2809417568C86803240 @default.
- W2809417568 hasConceptScore W2809417568C8891405 @default.
- W2809417568 hasConceptScore W2809417568C95444343 @default.
- W2809417568 hasIssue "1" @default.
- W2809417568 hasLocation W28094175681 @default.
- W2809417568 hasLocation W28094175682 @default.
- W2809417568 hasLocation W28094175683 @default.
- W2809417568 hasOpenAccess W2809417568 @default.
- W2809417568 hasPrimaryLocation W28094175681 @default.
- W2809417568 hasRelatedWork W2014731655 @default.
- W2809417568 hasRelatedWork W2047209980 @default.
- W2809417568 hasRelatedWork W2158893841 @default.
- W2809417568 hasRelatedWork W2265205727 @default.
- W2809417568 hasRelatedWork W2767735945 @default.
- W2809417568 hasRelatedWork W2964479693 @default.
- W2809417568 hasRelatedWork W3032907499 @default.
- W2809417568 hasRelatedWork W3118180598 @default.
- W2809417568 hasRelatedWork W3158438576 @default.
- W2809417568 hasRelatedWork W3177251880 @default.
- W2809417568 hasVolume "42" @default.
- W2809417568 isParatext "false" @default.
- W2809417568 isRetracted "false" @default.
- W2809417568 magId "2809417568" @default.
- W2809417568 workType "article" @default.