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- W2809439583 abstract "The microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the role of microorganisms that reside in the human gut has attracted much attention beyond classical infectious diseases. For example, numerous studies have reported changes in the gut microbiota during not only obesity, diabetes, and liver diseases but also cancer and even neurodegenerative diseases. The human gut microbiota is viewed as a potential source of novel therapeutics. Between 2013 and 2017, the number of publications focusing on the gut microbiota was, remarkably, 12 900, which represents four-fifths of the total number of publications over the last 40 years that investigated this topic. This review discusses recent evidence of the impact of the gut microbiota on metabolic disorders and focus on selected key mechanisms. This review also aims to provide a critical analysis of the current knowledge in this field, identify putative key issues or problems and discuss misinterpretations. The abundance of metagenomic data generated on comparing diseased and healthy subjects can lead to the erroneous claim that a bacterium is causally linked with the protection or the onset of a disease. In fact, environmental factors such as dietary habits, drug treatments, intestinal motility and stool frequency and consistency are all factors that influence the composition of the microbiota and should be considered. The cases of the bacteria Prevotella copri and Akkermansia muciniphila will be discussed as key examples." @default.
- W2809439583 created "2018-06-29" @default.
- W2809439583 creator A5070336660 @default.
- W2809439583 date "2018-06-22" @default.
- W2809439583 modified "2023-10-14" @default.
- W2809439583 title "Human gut microbiome: hopes, threats and promises" @default.
- W2809439583 cites W1606088617 @default.
- W2809439583 cites W1831268717 @default.
- W2809439583 cites W1856943231 @default.
- W2809439583 cites W1965027165 @default.
- W2809439583 cites W1966921473 @default.
- W2809439583 cites W1970929490 @default.
- W2809439583 cites W1972237932 @default.
- W2809439583 cites W1979966476 @default.
- W2809439583 cites W1985684171 @default.
- W2809439583 cites W1989759308 @default.
- W2809439583 cites W1992113107 @default.
- W2809439583 cites W1995586746 @default.
- W2809439583 cites W2011848880 @default.
- W2809439583 cites W2018213438 @default.
- W2809439583 cites W2018247592 @default.
- W2809439583 cites W2023615726 @default.
- W2809439583 cites W2035421462 @default.
- W2809439583 cites W2037336189 @default.
- W2809439583 cites W2041136224 @default.
- W2809439583 cites W2043174271 @default.
- W2809439583 cites W2043659905 @default.
- W2809439583 cites W2044719746 @default.
- W2809439583 cites W2048853985 @default.
- W2809439583 cites W2049698508 @default.
- W2809439583 cites W2062593620 @default.
- W2809439583 cites W2063856799 @default.
- W2809439583 cites W2070004832 @default.
- W2809439583 cites W2070537560 @default.
- W2809439583 cites W2071841602 @default.
- W2809439583 cites W2078599166 @default.
- W2809439583 cites W2082509173 @default.
- W2809439583 cites W2090488505 @default.
- W2809439583 cites W2099456560 @default.
- W2809439583 cites W2108887551 @default.
- W2809439583 cites W2112708847 @default.
- W2809439583 cites W2125784987 @default.
- W2809439583 cites W2131536322 @default.
- W2809439583 cites W2134241692 @default.
- W2809439583 cites W2136417551 @default.
- W2809439583 cites W2139166152 @default.
- W2809439583 cites W2139334262 @default.
- W2809439583 cites W2145089546 @default.
- W2809439583 cites W2147790901 @default.
- W2809439583 cites W2149074973 @default.
- W2809439583 cites W2153075279 @default.
- W2809439583 cites W2161332823 @default.
- W2809439583 cites W2165067288 @default.
- W2809439583 cites W2165456770 @default.
- W2809439583 cites W2167062509 @default.
- W2809439583 cites W2171016495 @default.
- W2809439583 cites W2175465469 @default.
- W2809439583 cites W2178459747 @default.
- W2809439583 cites W2188930066 @default.
- W2809439583 cites W2194591433 @default.
- W2809439583 cites W2200936799 @default.
- W2809439583 cites W2206854629 @default.
- W2809439583 cites W2214183716 @default.
- W2809439583 cites W2224656683 @default.
- W2809439583 cites W2228687373 @default.
- W2809439583 cites W2235111525 @default.
- W2809439583 cites W2276508045 @default.
- W2809439583 cites W2322422487 @default.
- W2809439583 cites W2344498019 @default.
- W2809439583 cites W2345616653 @default.
- W2809439583 cites W2345813655 @default.
- W2809439583 cites W2398803261 @default.
- W2809439583 cites W2427089839 @default.
- W2809439583 cites W2461078957 @default.
- W2809439583 cites W2462368291 @default.
- W2809439583 cites W2463282260 @default.
- W2809439583 cites W2468194934 @default.
- W2809439583 cites W2474000574 @default.
- W2809439583 cites W2521816539 @default.
- W2809439583 cites W2524785584 @default.
- W2809439583 cites W2535932582 @default.
- W2809439583 cites W2547640677 @default.
- W2809439583 cites W2549293350 @default.
- W2809439583 cites W2553515186 @default.
- W2809439583 cites W2558803112 @default.
- W2809439583 cites W2559267012 @default.
- W2809439583 cites W2567641807 @default.
- W2809439583 cites W2585164699 @default.
- W2809439583 cites W2585920057 @default.
- W2809439583 cites W2587959748 @default.
- W2809439583 cites W2588601551 @default.
- W2809439583 cites W2594894350 @default.
- W2809439583 cites W2599082900 @default.
- W2809439583 cites W2604209550 @default.
- W2809439583 cites W2613785717 @default.
- W2809439583 cites W2617130732 @default.
- W2809439583 cites W2618833496 @default.
- W2809439583 cites W2619680342 @default.