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- W2809681057 abstract "Mitochondrial genomes of animals have long been considered to evolve under the action of purifying selection. Nevertheless, there is increasing evidence that they can also undergo episodes of positive selection in response to shifts in physiological or environmental demands. Vampire bats experienced such a shift, as they are the only mammals feeding exclusively on blood and possessing anatomical adaptations to deal with the associated physiological requirements (e.g., ingestion of high amounts of liquid water and iron). We sequenced eight new chiropteran mitogenomes including two species of vampire bats, five representatives of other lineages of phyllostomids and one close outgroup. Conducting detailed comparative mitogenomic analyses, we found evidence for accelerated evolutionary rates at the nucleotide and amino acid levels in vampires. Moreover, the mitogenomes of vampire bats are characterized by an increased cytosine (C) content mirrored by a decrease in thymine (T) compared with other chiropterans. Proteins encoded by the vampire bat mitogenomes also exhibit a significant increase in threonine (Thr) and slight reductions in frequency of the hydrophobic residues isoleucine (Ile), valine (Val), methionine (Met), and phenylalanine (Phe). We show that these peculiar substitution patterns can be explained by the co-occurrence of both neutral (mutational bias) and adaptive (positive selection) processes. We propose that vampire bat mitogenomes may have been impacted by selection on mitochondrial proteins to accommodate the metabolism and nutritional qualities of blood meals." @default.
- W2809681057 created "2018-06-29" @default.
- W2809681057 creator A5011098981 @default.
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- W2809681057 creator A5044246595 @default.
- W2809681057 creator A5053363983 @default.
- W2809681057 date "2018-06-20" @default.
- W2809681057 modified "2023-10-11" @default.
- W2809681057 title "In Cold Blood: Compositional Bias and Positive Selection Drive the High Evolutionary Rate of Vampire Bats Mitochondrial Genomes" @default.
- W2809681057 cites W1160294689 @default.
- W2809681057 cites W1482656206 @default.
- W2809681057 cites W1519266993 @default.
- W2809681057 cites W1546341583 @default.
- W2809681057 cites W1692155593 @default.
- W2809681057 cites W1938177411 @default.
- W2809681057 cites W1966621093 @default.
- W2809681057 cites W1967511718 @default.
- W2809681057 cites W1974440637 @default.
- W2809681057 cites W1983622148 @default.
- W2809681057 cites W1983732539 @default.
- W2809681057 cites W1987340287 @default.
- W2809681057 cites W1988652743 @default.
- W2809681057 cites W1992920361 @default.
- W2809681057 cites W1993268068 @default.
- W2809681057 cites W1993631636 @default.
- W2809681057 cites W1995113359 @default.
- W2809681057 cites W1997455034 @default.
- W2809681057 cites W1997741434 @default.
- W2809681057 cites W1999402715 @default.
- W2809681057 cites W2000300563 @default.
- W2809681057 cites W2003634684 @default.
- W2809681057 cites W2013061932 @default.
- W2809681057 cites W2013412454 @default.
- W2809681057 cites W2017836936 @default.
- W2809681057 cites W2021255873 @default.
- W2809681057 cites W2022167917 @default.
- W2809681057 cites W2022870540 @default.
- W2809681057 cites W2023552355 @default.
- W2809681057 cites W2027228430 @default.
- W2809681057 cites W2029134836 @default.
- W2809681057 cites W2029549914 @default.
- W2809681057 cites W2030868673 @default.
- W2809681057 cites W2035905992 @default.
- W2809681057 cites W2036897871 @default.
- W2809681057 cites W2045595543 @default.
- W2809681057 cites W2046043715 @default.
- W2809681057 cites W2046761749 @default.
- W2809681057 cites W2052004838 @default.
- W2809681057 cites W2052850516 @default.
- W2809681057 cites W2057139394 @default.
- W2809681057 cites W2057590210 @default.
- W2809681057 cites W2067659770 @default.
- W2809681057 cites W2070842365 @default.
- W2809681057 cites W2072442825 @default.
- W2809681057 cites W2075173446 @default.
- W2809681057 cites W2076704852 @default.
- W2809681057 cites W2076793571 @default.
- W2809681057 cites W2076821547 @default.
- W2809681057 cites W2077283682 @default.
- W2809681057 cites W2077530381 @default.
- W2809681057 cites W2087892863 @default.
- W2809681057 cites W2087895117 @default.
- W2809681057 cites W2089985991 @default.
- W2809681057 cites W2094739612 @default.
- W2809681057 cites W2097977090 @default.
- W2809681057 cites W2098750663 @default.
- W2809681057 cites W2104398544 @default.
- W2809681057 cites W2108493253 @default.
- W2809681057 cites W2108795433 @default.
- W2809681057 cites W2110335151 @default.
- W2809681057 cites W2114722531 @default.
- W2809681057 cites W2114828923 @default.
- W2809681057 cites W2115888213 @default.
- W2809681057 cites W2116111392 @default.
- W2809681057 cites W2119811919 @default.
- W2809681057 cites W2123696055 @default.
- W2809681057 cites W2124772083 @default.
- W2809681057 cites W2125512106 @default.
- W2809681057 cites W2126606792 @default.
- W2809681057 cites W2127148540 @default.
- W2809681057 cites W2128449821 @default.
- W2809681057 cites W2128880918 @default.
- W2809681057 cites W2129087343 @default.
- W2809681057 cites W2130604977 @default.
- W2809681057 cites W2130680472 @default.
- W2809681057 cites W2132632499 @default.
- W2809681057 cites W2133552700 @default.
- W2809681057 cites W2133870991 @default.
- W2809681057 cites W2134420735 @default.
- W2809681057 cites W2137633181 @default.
- W2809681057 cites W2137690894 @default.
- W2809681057 cites W2138062889 @default.
- W2809681057 cites W2139646315 @default.
- W2809681057 cites W2141683865 @default.
- W2809681057 cites W2142249333 @default.
- W2809681057 cites W2144474523 @default.