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- W2809682314 endingPage "135" @default.
- W2809682314 startingPage "135" @default.
- W2809682314 abstract "Brugada syndrome (BrS) is a cardiac disease caused by an inherited ion channelopathy associated with a propensity to develop ventricular fibrillation. Implantable cardioverter defibrillator implantation is recommended in BrS, based on the clinical presentation in the presence of diagnostic ECG criteria. Implantable cardioverter defibrillator implantation is not always indicated or sufficient in BrS, and is associated with a high device complication rate. Pharmacological therapy aimed at rebalancing the membrane action potential can prevent arrhythmogenesis in BrS. Quinidine, a class 1A antiarrhythmic drug with significant Ito blocking properties, is the most extensively used drug for the prevention of arrhythmias in BrS. The present review provides contemporary data gathered on all drugs effective in the therapy of BrS, and on ineffective or contraindicated antiarrhythmic drugs." @default.
- W2809682314 created "2018-06-29" @default.
- W2809682314 creator A5027470709 @default.
- W2809682314 creator A5068363358 @default.
- W2809682314 creator A5074629412 @default.
- W2809682314 date "2018-01-01" @default.
- W2809682314 modified "2023-10-15" @default.
- W2809682314 title "Pharmacological Therapy in Brugada Syndrome" @default.
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