FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2809838067> ?p ?o ?g. }

• W2809838067 endingPage "49" @default.
• W2809838067 startingPage "38" @default.
• W2809838067 abstract "When a social sound category initially gains behavioral significance to an animal, plasticity events presumably enhance the ability to recognize that sound category in the future. In the context of learning natural social stimuli, neuromodulators such as norepinephrine and estrogen have been associated with experience-dependent plasticity and processing of newly salient social cues, yet continued plasticity once stimuli are familiar could disrupt the stability of sensorineural representations. Here we employed a maternal mouse model of natural sensory cortical plasticity for infant vocalizations to ask whether the engagement of the noradrenergic locus coeruleus (LC) by the playback of pup-calls is affected by either prior experience with the sounds or estrogen availability, using a well-studied cellular activity and plasticity marker, the immediate early gene c-Fos. We counted call-induced c-Fos immunoreactive (c-Fos-IR) cells in both LC and physiologically validated fields within the auditory cortex (AC) of estradiol or blank-implanted virgin female mice with either 0 or 5-days prior experience caring for vocalizing pups. Estradiol and pup experience interacted both in the induction of c-Fos-IR in the LC, as well as in behavioral measures of locomotion during playback, consistent with the neuromodulatory center's activity being an online reflection of both hormonal and experience-dependent influences on arousal. Throughout core AC, as well as in a high frequency sub-region of AC and in secondary AC, a main effect of pup experience was to reduce call-induced c-Fos-IR, irrespective of estradiol availability. This is consistent with the hypothesis that sound familiarity leads to less c-Fos-mediated plasticity, and less disrupted sensory representations of a meaningful call category. Taken together, our data support the view that any coupling between these sensory and neuromodulatory areas is situationally dependent, and their engagement depends differentially on both internal state factors like hormones and external state factors like prior experience." @default.
• W2809838067 created "2018-07-10" @default.
• W2809838067 creator A5011896817 @default.
• W2809838067 creator A5014000022 @default.
• W2809838067 creator A5033608125 @default.
• W2809838067 creator A5067724195 @default.
• W2809838067 creator A5074819186 @default.
• W2809838067 creator A5083765822 @default.
• W2809838067 creator A5088320679 @default.
• W2809838067 date "2018-09-01" @default.
• W2809838067 modified "2023-10-16" @default.
• W2809838067 title "Familiarity with social sounds alters c-Fos expression in auditory cortex and interacts with estradiol in locus coeruleus" @default.
• W2809838067 cites W1497204367 @default.
• W2809838067 cites W1509128224 @default.
• W2809838067 cites W1534476687 @default.
• W2809838067 cites W1845419411 @default.
• W2809838067 cites W1913966070 @default.
• W2809838067 cites W1914747759 @default.
• W2809838067 cites W1965573885 @default.
• W2809838067 cites W1970297898 @default.
• W2809838067 cites W1971000831 @default.
• W2809838067 cites W1971959365 @default.
• W2809838067 cites W1977595194 @default.
• W2809838067 cites W1980129559 @default.
• W2809838067 cites W1985918072 @default.
• W2809838067 cites W1986511921 @default.
• W2809838067 cites W1988371720 @default.
• W2809838067 cites W1989722647 @default.
• W2809838067 cites W1990045422 @default.
• W2809838067 cites W1992037723 @default.
• W2809838067 cites W1997599315 @default.
• W2809838067 cites W2006225961 @default.
• W2809838067 cites W2007541448 @default.
• W2809838067 cites W2008305674 @default.
• W2809838067 cites W2009912939 @default.
• W2809838067 cites W2012116465 @default.
• W2809838067 cites W2012270915 @default.
• W2809838067 cites W2017575496 @default.
• W2809838067 cites W2019949762 @default.
• W2809838067 cites W2020251341 @default.
• W2809838067 cites W2020957587 @default.
• W2809838067 cites W2021270644 @default.
• W2809838067 cites W2022705038 @default.
• W2809838067 cites W2024392023 @default.
• W2809838067 cites W2024494817 @default.
• W2809838067 cites W2033388169 @default.
• W2809838067 cites W2036909895 @default.
• W2809838067 cites W2037148849 @default.
• W2809838067 cites W2043599896 @default.
• W2809838067 cites W2044046116 @default.
• W2809838067 cites W2050516070 @default.
• W2809838067 cites W2051976177 @default.
• W2809838067 cites W2054712564 @default.
• W2809838067 cites W2055524760 @default.
• W2809838067 cites W2056748161 @default.
• W2809838067 cites W2057318097 @default.
• W2809838067 cites W2058280968 @default.
• W2809838067 cites W2058601367 @default.
• W2809838067 cites W2060946635 @default.
• W2809838067 cites W2061302245 @default.
• W2809838067 cites W2061722255 @default.
• W2809838067 cites W2063306678 @default.
• W2809838067 cites W2065939107 @default.
• W2809838067 cites W2068191519 @default.
• W2809838067 cites W2069886463 @default.
• W2809838067 cites W2077627719 @default.
• W2809838067 cites W2084250402 @default.
• W2809838067 cites W2085900799 @default.
• W2809838067 cites W2088259542 @default.
• W2809838067 cites W2091382604 @default.
• W2809838067 cites W2091519594 @default.
• W2809838067 cites W2093213408 @default.
• W2809838067 cites W2093599646 @default.
• W2809838067 cites W2095462094 @default.
• W2809838067 cites W2096063538 @default.
• W2809838067 cites W2102183960 @default.
• W2809838067 cites W2104184356 @default.
• W2809838067 cites W2122786101 @default.
• W2809838067 cites W2129340811 @default.
• W2809838067 cites W2129928127 @default.
• W2809838067 cites W2145865543 @default.
• W2809838067 cites W2152504800 @default.
• W2809838067 cites W2194534517 @default.
• W2809838067 cites W2285696854 @default.
• W2809838067 cites W2300589733 @default.
• W2809838067 cites W2342247067 @default.
• W2809838067 cites W2557190676 @default.
• W2809838067 cites W2770871490 @default.
• W2809838067 cites W4245130121 @default.
• W2809838067 cites W4245189409 @default.
• W2809838067 doi "https://doi.org/10.1016/j.heares.2018.06.020" @default.
• W2809838067 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6470399" @default.
• W2809838067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29983289" @default.
• W2809838067 hasPublicationYear "2018" @default.
• W2809838067 type Work @default.
• W2809838067 sameAs 2809838067 @default.
• W2809838067 citedByCount "14" @default.
• W2809838067 countsByYear W28098380672019 @default.

• next