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• W2809849175 abstract "Fear extinction is the well-known process of fear reduction through repeated re-exposure to a feared stimulus without the aversive outcome. The last two decades have witnessed a surge of interest in extinction learning. First, extinction learning is observed across species, and especially research on rodents has made great strides in characterising the physical substrate underlying extinction learning. Second, extinction learning is considered of great clinical significance since it constitutes a crucial component of exposure treatment. While effective in reducing fear responding in the short term, extinction learning can lose its grip, resulting in a return of fear (i.e., laboratory model for relapse of anxiety symptoms in patients). Optimization of extinction learning is, therefore, the subject of intense investigation. It is thought that the success of extinction learning is, at least partly, determined by the mismatch between what is expected and what actually happens (prediction error). However, while much of our knowledge about the neural circuitry of extinction learning and factors that contribute to successful extinction learning comes from animal models, translating these findings to humans has been challenging for a number of reasons. Here, we present an overview of what is known about the animal circuitry underlying extinction of fear, and the role of prediction error. In addition, we conducted a systematic literature search to evaluate the degree to which state-of-the-art neuroimaging methods have contributed to translating these findings to humans. Results show substantial overlap between networks in animals and humans at a macroscale, but current imaging techniques preclude comparisons at a smaller scale, especially in sub-cortical areas that are functionally heterogeneous. Moreover, human neuroimaging shows the involvement of numerous areas that are not typically studied in animals. Results obtained in research aimed to map the extinction circuit are largely dependent on the methods employed, not only across species, but also across human neuroimaging studies. Directions for future research are discussed." @default.
• W2809849175 created "2018-07-10" @default.
• W2809849175 creator A5073347333 @default.
• W2809849175 creator A5083509292 @default.
• W2809849175 creator A5089257009 @default.
• W2809849175 date "2018-11-01" @default.
• W2809849175 modified "2023-09-29" @default.
• W2809849175 title "A translational perspective on neural circuits of fear extinction: Current promises and challenges" @default.
• W2809849175 cites W1513763202 @default.
• W2809849175 cites W1519591349 @default.
• W2809849175 cites W1525373779 @default.
• W2809849175 cites W1591199750 @default.
• W2809849175 cites W1592248289 @default.
• W2809849175 cites W1597129241 @default.
• W2809849175 cites W1608785134 @default.
• W2809849175 cites W1677141559 @default.
• W2809849175 cites W1920095995 @default.
• W2809849175 cites W1963651954 @default.
• W2809849175 cites W1967996189 @default.
• W2809849175 cites W1968125675 @default.
• W2809849175 cites W1971496410 @default.
• W2809849175 cites W1973451278 @default.
• W2809849175 cites W1975705681 @default.
• W2809849175 cites W1976774603 @default.
• W2809849175 cites W1977106703 @default.
• W2809849175 cites W1977502547 @default.
• W2809849175 cites W1978489779 @default.
• W2809849175 cites W1978781499 @default.
• W2809849175 cites W1981032252 @default.
• W2809849175 cites W1982327643 @default.
• W2809849175 cites W1984624029 @default.
• W2809849175 cites W1984832660 @default.
• W2809849175 cites W1988193688 @default.
• W2809849175 cites W1988353820 @default.
• W2809849175 cites W1992402923 @default.
• W2809849175 cites W1992892094 @default.
• W2809849175 cites W1995629399 @default.
• W2809849175 cites W1998065705 @default.
• W2809849175 cites W1998261300 @default.
• W2809849175 cites W2002801119 @default.
• W2809849175 cites W2002923643 @default.
• W2809849175 cites W2004175847 @default.
• W2809849175 cites W2004397468 @default.
• W2809849175 cites W2005138253 @default.
• W2809849175 cites W2006789534 @default.
• W2809849175 cites W2006844732 @default.
• W2809849175 cites W2007481513 @default.
• W2809849175 cites W2011525076 @default.
• W2809849175 cites W2012627475 @default.
• W2809849175 cites W2012740961 @default.
• W2809849175 cites W2013016395 @default.
• W2809849175 cites W2014979870 @default.
• W2809849175 cites W2015451929 @default.
• W2809849175 cites W2016264450 @default.
• W2809849175 cites W2016660677 @default.
• W2809849175 cites W2018162107 @default.
• W2809849175 cites W2018187135 @default.
• W2809849175 cites W2018346570 @default.
• W2809849175 cites W2019438546 @default.
• W2809849175 cites W2024565969 @default.
• W2809849175 cites W2025266605 @default.
• W2809849175 cites W2025672359 @default.
• W2809849175 cites W2029799717 @default.
• W2809849175 cites W2029952870 @default.
• W2809849175 cites W2030183678 @default.
• W2809849175 cites W2031547008 @default.
• W2809849175 cites W2032476754 @default.
• W2809849175 cites W2033809956 @default.
• W2809849175 cites W2035805507 @default.
• W2809849175 cites W2036084760 @default.
• W2809849175 cites W2036537456 @default.
• W2809849175 cites W2036713747 @default.
• W2809849175 cites W2036824041 @default.
• W2809849175 cites W2036855091 @default.
• W2809849175 cites W2036872212 @default.
• W2809849175 cites W2038938389 @default.
• W2809849175 cites W2039261561 @default.
• W2809849175 cites W2040137808 @default.
• W2809849175 cites W2041516961 @default.
• W2809849175 cites W2041716195 @default.
• W2809849175 cites W2042479971 @default.
• W2809849175 cites W2043884058 @default.
• W2809849175 cites W2044731038 @default.
• W2809849175 cites W2047708659 @default.
• W2809849175 cites W2049511110 @default.
• W2809849175 cites W2049549817 @default.
• W2809849175 cites W2049812132 @default.
• W2809849175 cites W2050618347 @default.
• W2809849175 cites W2050753235 @default.
• W2809849175 cites W2051902405 @default.
• W2809849175 cites W2052869567 @default.
• W2809849175 cites W2054434123 @default.
• W2809849175 cites W2057906075 @default.
• W2809849175 cites W2059671083 @default.
• W2809849175 cites W2061214701 @default.
• W2809849175 cites W2061559918 @default.
• W2809849175 cites W2064135174 @default.
• W2809849175 cites W2066525901 @default.

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