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- W2809947304 abstract "We analyzed the role of hydrodynamic interactions in a microfluidic channel flow containing a dilute suspension of micron-scale colloidal spheres (0.03%, 0.1%, 0.3% volume fraction) engineered to adhere onto a collector patch on the channel wall at wall shear rates of 9.3–930 s−1. Particle-wall adhesion was mediated by single-stranded DNA oligomers grafted onto the spheres and the glass channel wall, producing well-defined interactions via DNA strand base pairing. Particle positions in the flow were evolved using Brownian dynamics simulations in which hydrodynamic interactions between moving particles and the channel walls and/or adhered particles were computed off-line using a series of local simulations that explicitly resolve the fluid flow at the particle scale. By systematically varying the nature of hydrodynamic interactions captured in the Brownian dynamics simulations, we find that the interactions between moving and adhered particles represents the single most important physical element in such models. Once captured sufficiently accurately, the resulting models are able to predict coarse variables such as the overall particle coverage evolution, as well as more subtle characteristics, such as the microstructural distribution of the adhered particles." @default.
- W2809947304 created "2018-07-10" @default.
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- W2809947304 date "2018-11-01" @default.
- W2809947304 modified "2023-10-16" @default.
- W2809947304 title "Deposition of sticky spheres in channel flow: Modeling of surface coverage evolution requires accurate sphere-sphere collision hydrodynamics" @default.
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- W2809947304 doi "https://doi.org/10.1016/j.jcis.2018.06.097" @default.
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