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• W2810048468 abstract "Purpose The study sought to investigate the role of breast magnetic resonance imaging (MRI) in patients diagnosed with atypical ductal hyperplasia (ADH) at core needle biopsy (CNB). Methods The breast MRI database at our centre was queried for studies performed between January 2010 and December 2016 for the clinical indication of ADH diagnosed at CNB. Medical files were reviewed for demographic data, clinical information, and radiology and pathology reports. Pathological results of the surgical specimens were considered the gold standard for comparison with breast MRI findings. In women not undergoing excision, at least 2 years of follow-up was used to ascertain the benign nature of the finding. Results Fifty patients were included in the study. Thirty-one (62%) patients had surgical excision of the ADH lesion, and 7 (23%) were upgraded to malignancy. Breast MRI accurately identified 6 of the 7 cases. Six of the 12 women (50%) with positive MRI findings at the biopsy site were upgraded to malignancy on surgical pathology, compared with only 1 of 19 (5%) with negative MRI findings. Forty-nine percent of the women with a negative MRI did not undergo surgical excision of the ADH lesion, compared with 8% of the women with a positive MRI ( P = .009), with no cancer diagnosed during follow-up. The sensitivity, specificity, negative predictive value, and positive predictive value of breast MRI for predicting upgrade to malignancy were 86%, 83%, 97%, and 46%, respectively. Conclusions MRI may have a role in the management of women diagnosed with ADH on CNB, to minimize diagnostic excisional biopsies." @default.
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• W2810048468 date "2018-08-01" @default.
• W2810048468 modified "2023-10-02" @default.
• W2810048468 title "Use of Breast Magnetic Resonance Imaging in Women Diagnosed with Atypical Ductal Hyperplasia at Core Needle Biopsy Helps Select Women for Surgical Excision" @default.
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• W2810048468 doi "https://doi.org/10.1016/j.carj.2018.03.003" @default.
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