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- W2810231876 abstract "Helicobacter pylori infection has a central role in gastric cancer development, so eradication of this infection is expected to reduce gastric cancer development. In 2012, the Japanese government decided to introduce H. pylori eradication for chronic gastritis among asymptomatic people, including having this procedure covered by health insurance. The effects of dissemination of H. pylori eradication were investigated before and after the introduction H .pylori eradication in Japan. Since the total numbers of H. pylori cases eradicated is unclear in the national health insurance claims data, the prevalence of gastritis and total number of examinations for H. pylori infection per month were assessed as surrogate indicators. H. pylori infection is usually examined by testing for breath urea, serum H. pylori antibody, and fecal H. pylori antigen. The prevalence of gastritis and duodenitis was compared among 2008, 2011, and 2014 based on national patient surveys. The trends of the numbers of above mentioned examinations per month were compared to national health insurance claims data. Prevalence of gastritis and duodenitis was similar between 2008 and 2011, that is, before the introduction of H. pylori eradication. However, a rapid increase in this prevalence was observed in individuals aged 45 to 64 years between 2011 and 2014. Notably, the frequency of examination for H. pylori infection approximately doubled after 2012. Rapid increase of all examinations was observed for all individuals aged 30 years and over, particularly among those aged 50-64 years. These results suggested rapid dissemination of H. pylori eradication for chronic gastritis among asymptomatic people. H. pylori eradication has had a limited impact in reducing the incidence of gastric cancer. Although H. pylori eradication is not needed for all asymptomatic people, changes in health insurance coverage appear to have resulted overtreatment without consideration of possible harms." @default.
- W2810231876 created "2018-07-10" @default.
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- W2810231876 date "2018-05-01" @default.
- W2810231876 modified "2023-09-28" @default.
- W2810231876 title "Rapid Dissemination of H. Pylori Eradication for Chronic Gastritis Among Asymptomatic People" @default.
- W2810231876 doi "https://doi.org/10.1016/j.jval.2018.04.882" @default.
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