Matches in SemOpenAlex for { <https://semopenalex.org/work/W2810248918> ?p ?o ?g. }
- W2810248918 endingPage "23547" @default.
- W2810248918 startingPage "23539" @default.
- W2810248918 abstract "Many challenges in biosensing originate from the fact that the all-important nanoarchitecture of the biosensor surface, including precise density and orientation of bioreceptors, is not entirely comprehended. Here, we introduced a three-dimensional DNA origami as a bioreceptor carrier to functionalize the fiber optic surface plasmon resonance (FO-SPR) sensor with nanoscale precision. Starting from a 24-helix bundle, two distinct DNA origami structures were designed to position thrombin-specific aptamers with different densities and distances (27 and 113 nm) from the FO-SPR surface. The origami-based biosensors not only proved to be capable of reproducible, label-free thrombin detection but revealed also valuable innovative features: (1) a significantly better performance in the absence of backfilling, known as essential in the biosensing field, suggesting improved bioreceptor orientation and accessibility, and (2) a wider linear range compared to previously reported thrombin biosensors. We envisage that our method will be beneficial for both scientists and clinicians looking for new surface (bio)chemistry and improved diagnostics." @default.
- W2810248918 created "2018-07-10" @default.
- W2810248918 creator A5009911306 @default.
- W2810248918 creator A5046770124 @default.
- W2810248918 creator A5064200316 @default.
- W2810248918 creator A5068207701 @default.
- W2810248918 creator A5070744700 @default.
- W2810248918 creator A5075803366 @default.
- W2810248918 date "2018-06-27" @default.
- W2810248918 modified "2023-10-15" @default.
- W2810248918 title "Three-Dimensional DNA Origami as Programmable Anchoring Points for Bioreceptors in Fiber Optic Surface Plasmon Resonance Biosensing" @default.
- W2810248918 cites W1480588916 @default.
- W2810248918 cites W1567090568 @default.
- W2810248918 cites W1975679096 @default.
- W2810248918 cites W1976815031 @default.
- W2810248918 cites W1997577546 @default.
- W2810248918 cites W2007126220 @default.
- W2810248918 cites W2007542353 @default.
- W2810248918 cites W2008662133 @default.
- W2810248918 cites W2011922821 @default.
- W2810248918 cites W2019926801 @default.
- W2810248918 cites W2023747155 @default.
- W2810248918 cites W2025789926 @default.
- W2810248918 cites W2027576505 @default.
- W2810248918 cites W2030699288 @default.
- W2810248918 cites W2038125628 @default.
- W2810248918 cites W2042042512 @default.
- W2810248918 cites W2049721533 @default.
- W2810248918 cites W2054731715 @default.
- W2810248918 cites W2055721693 @default.
- W2810248918 cites W2062802768 @default.
- W2810248918 cites W2081104658 @default.
- W2810248918 cites W2088084709 @default.
- W2810248918 cites W2091704382 @default.
- W2810248918 cites W2092884623 @default.
- W2810248918 cites W2098294861 @default.
- W2810248918 cites W2103931611 @default.
- W2810248918 cites W2123795937 @default.
- W2810248918 cites W2125263518 @default.
- W2810248918 cites W2126479976 @default.
- W2810248918 cites W2126961173 @default.
- W2810248918 cites W2127159287 @default.
- W2810248918 cites W2129096474 @default.
- W2810248918 cites W2130906772 @default.
- W2810248918 cites W2145554986 @default.
- W2810248918 cites W2147005510 @default.
- W2810248918 cites W2150856068 @default.
- W2810248918 cites W2155697264 @default.
- W2810248918 cites W2155704077 @default.
- W2810248918 cites W2171439027 @default.
- W2810248918 cites W2194538548 @default.
- W2810248918 cites W2270607015 @default.
- W2810248918 cites W2305844627 @default.
- W2810248918 cites W2334016183 @default.
- W2810248918 cites W2395492045 @default.
- W2810248918 cites W2405180841 @default.
- W2810248918 cites W2474394510 @default.
- W2810248918 cites W2569847973 @default.
- W2810248918 cites W2739089729 @default.
- W2810248918 cites W2769874317 @default.
- W2810248918 cites W2770270092 @default.
- W2810248918 cites W4241821763 @default.
- W2810248918 cites W4256127236 @default.
- W2810248918 doi "https://doi.org/10.1021/acsami.8b04757" @default.
- W2810248918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29947211" @default.
- W2810248918 hasPublicationYear "2018" @default.
- W2810248918 type Work @default.
- W2810248918 sameAs 2810248918 @default.
- W2810248918 citedByCount "55" @default.
- W2810248918 countsByYear W28102489182018 @default.
- W2810248918 countsByYear W28102489182019 @default.
- W2810248918 countsByYear W28102489182020 @default.
- W2810248918 countsByYear W28102489182021 @default.
- W2810248918 countsByYear W28102489182022 @default.
- W2810248918 countsByYear W28102489182023 @default.
- W2810248918 crossrefType "journal-article" @default.
- W2810248918 hasAuthorship W2810248918A5009911306 @default.
- W2810248918 hasAuthorship W2810248918A5046770124 @default.
- W2810248918 hasAuthorship W2810248918A5064200316 @default.
- W2810248918 hasAuthorship W2810248918A5068207701 @default.
- W2810248918 hasAuthorship W2810248918A5070744700 @default.
- W2810248918 hasAuthorship W2810248918A5075803366 @default.
- W2810248918 hasBestOaLocation W28102489182 @default.
- W2810248918 hasConcept C106847996 @default.
- W2810248918 hasConcept C110879396 @default.
- W2810248918 hasConcept C118630614 @default.
- W2810248918 hasConcept C128972844 @default.
- W2810248918 hasConcept C136676167 @default.
- W2810248918 hasConcept C155672457 @default.
- W2810248918 hasConcept C160756335 @default.
- W2810248918 hasConcept C171250308 @default.
- W2810248918 hasConcept C186187911 @default.
- W2810248918 hasConcept C192562407 @default.
- W2810248918 hasConcept C49040817 @default.
- W2810248918 hasConcept C54355233 @default.
- W2810248918 hasConcept C86803240 @default.
- W2810248918 hasConceptScore W2810248918C106847996 @default.
- W2810248918 hasConceptScore W2810248918C110879396 @default.