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- W2810335577 abstract "Immediate contact reactions are a heterogeneous group of inflammatory conditions characterized by two main clinical presentations: contact urticaria (CoU) for patients presenting with wheals/angioedema, and protein contact dermatitis (PCD) for patients presenting with predominantly dermatitis/eczema. Generalized lesions or systemic symptoms are feasible also in the contact urticaria syndrome (CUS). This chapter summarizes the most important aspects regarding the mechanisms of these two conditions. Nonimmunological, immunological, and uncertain mechanisms have been proposed as possible pathogenic mechanisms in CoU, and an immunological mechanism involving a combination of type I and type IV allergic skin reactions has been proposed in PCD. Understanding the possible mechanisms will help our approach to the different clinical manifestations and diagnostic procedures performed to confirm the diagnosis." @default.
- W2810335577 created "2018-07-10" @default.
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- W2810335577 creator A5073423143 @default.
- W2810335577 date "2018-01-01" @default.
- W2810335577 modified "2023-09-24" @default.
- W2810335577 title "Wheals and Eczema: Pathogenic Mechanism in Immediate Contact Reactions" @default.
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- W2810335577 doi "https://doi.org/10.1007/978-3-319-89764-6_6" @default.
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