FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2810409999> ?p ?o ?g. }

• W2810409999 endingPage "e5050" @default.
• W2810409999 startingPage "e5050" @default.
• W2810409999 abstract "Matrix metallopeptidase 9 (MMP9) was found to be associated with tumor aggressiveness. In this study, we focused on the correlation between MMP9 expression and clear cell renal carcinoma (ccRCC). Through the Gene Expression Omnibus (GEO) database, the Cancer Genome Atlas (TCGA) database and immunohistochemical (IHC) staining, we observed that compared with adjacent normal renal tissues, in ccRCC tissues the mRNA and protein levels of MMP9 were enhanced, and the mRNA levels of GTP-binding protein smg p21B(RAP1B), B rapidly accelerated fibrosarcoma (RAF), methyl ethyl ketone2 (MEK2), extracellular regulated protein kinases1 (ERK1), ERK2, v-ets avian erythroblastosis virus E26 oncogene homolog1 (ETS1) and ETS2 also increased. The Kaplan–Meier survival analysis suggested that high MMP9 expression was an unfavorable prognostic biomarker for ccRCC patients. Our results indicated that the increased expression level of MMP9 in ccRCC may be due to the activation of the Mitogen-activated protein kinases (MAPK)/ERK signaling pathway, and MMP9 may be an attractive target for ccRCC therapy." @default.
• W2810409999 created "2018-07-10" @default.
• W2810409999 creator A5001003322 @default.
• W2810409999 creator A5014708668 @default.
• W2810409999 creator A5051411280 @default.
• W2810409999 creator A5081844561 @default.
• W2810409999 creator A5083702713 @default.
• W2810409999 creator A5089866671 @default.
• W2810409999 date "2018-07-04" @default.
• W2810409999 modified "2023-09-30" @default.
• W2810409999 title "High expression level of MMP9 is associated with poor prognosis in patients with clear cell renal carcinoma" @default.
• W2810409999 cites W1547736903 @default.
• W2810409999 cites W1966669109 @default.
• W2810409999 cites W2016859011 @default.
• W2810409999 cites W2021485215 @default.
• W2810409999 cites W2041798139 @default.
• W2810409999 cites W2050991236 @default.
• W2810409999 cites W2060615802 @default.
• W2810409999 cites W2092892924 @default.
• W2810409999 cites W2119742016 @default.
• W2810409999 cites W2136109165 @default.
• W2810409999 cites W2138292652 @default.
• W2810409999 cites W2148525194 @default.
• W2810409999 cites W2151773547 @default.
• W2810409999 cites W2155567879 @default.
• W2810409999 cites W2157709266 @default.
• W2810409999 cites W2159478099 @default.
• W2810409999 cites W2164317031 @default.
• W2810409999 cites W2170989872 @default.
• W2810409999 cites W2261187761 @default.
• W2810409999 cites W2438157489 @default.
• W2810409999 cites W2595658733 @default.
• W2810409999 cites W2765756881 @default.
• W2810409999 cites W2911611736 @default.
• W2810409999 doi "https://doi.org/10.7717/peerj.5050" @default.
• W2810409999 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6035719" @default.
• W2810409999 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30013825" @default.
• W2810409999 hasPublicationYear "2018" @default.
• W2810409999 type Work @default.
• W2810409999 sameAs 2810409999 @default.
• W2810409999 citedByCount "23" @default.
• W2810409999 countsByYear W28104099992018 @default.
• W2810409999 countsByYear W28104099992019 @default.
• W2810409999 countsByYear W28104099992020 @default.
• W2810409999 countsByYear W28104099992021 @default.
• W2810409999 countsByYear W28104099992022 @default.
• W2810409999 countsByYear W28104099992023 @default.
• W2810409999 crossrefType "journal-article" @default.
• W2810409999 hasAuthorship W2810409999A5001003322 @default.
• W2810409999 hasAuthorship W2810409999A5014708668 @default.
• W2810409999 hasAuthorship W2810409999A5051411280 @default.
• W2810409999 hasAuthorship W2810409999A5081844561 @default.
• W2810409999 hasAuthorship W2810409999A5083702713 @default.
• W2810409999 hasAuthorship W2810409999A5089866671 @default.
• W2810409999 hasBestOaLocation W28104099991 @default.
• W2810409999 hasConcept C104317684 @default.
• W2810409999 hasConcept C121608353 @default.
• W2810409999 hasConcept C126322002 @default.
• W2810409999 hasConcept C127561419 @default.
• W2810409999 hasConcept C142724271 @default.
• W2810409999 hasConcept C184235292 @default.
• W2810409999 hasConcept C204232928 @default.
• W2810409999 hasConcept C2775997469 @default.
• W2810409999 hasConcept C2777472916 @default.
• W2810409999 hasConcept C2781018059 @default.
• W2810409999 hasConcept C2781197716 @default.
• W2810409999 hasConcept C2781278892 @default.
• W2810409999 hasConcept C29537977 @default.
• W2810409999 hasConcept C502942594 @default.
• W2810409999 hasConcept C55493867 @default.
• W2810409999 hasConcept C57074206 @default.
• W2810409999 hasConcept C71924100 @default.
• W2810409999 hasConcept C86803240 @default.
• W2810409999 hasConcept C95444343 @default.
• W2810409999 hasConceptScore W2810409999C104317684 @default.
• W2810409999 hasConceptScore W2810409999C121608353 @default.
• W2810409999 hasConceptScore W2810409999C126322002 @default.
• W2810409999 hasConceptScore W2810409999C127561419 @default.
• W2810409999 hasConceptScore W2810409999C142724271 @default.
• W2810409999 hasConceptScore W2810409999C184235292 @default.
• W2810409999 hasConceptScore W2810409999C204232928 @default.
• W2810409999 hasConceptScore W2810409999C2775997469 @default.
• W2810409999 hasConceptScore W2810409999C2777472916 @default.
• W2810409999 hasConceptScore W2810409999C2781018059 @default.
• W2810409999 hasConceptScore W2810409999C2781197716 @default.
• W2810409999 hasConceptScore W2810409999C2781278892 @default.
• W2810409999 hasConceptScore W2810409999C29537977 @default.
• W2810409999 hasConceptScore W2810409999C502942594 @default.
• W2810409999 hasConceptScore W2810409999C55493867 @default.
• W2810409999 hasConceptScore W2810409999C57074206 @default.
• W2810409999 hasConceptScore W2810409999C71924100 @default.
• W2810409999 hasConceptScore W2810409999C86803240 @default.
• W2810409999 hasConceptScore W2810409999C95444343 @default.
• W2810409999 hasFunder F4320321878 @default.
• W2810409999 hasFunder F4320326546 @default.
• W2810409999 hasLocation W28104099991 @default.
• W2810409999 hasLocation W28104099992 @default.
• W2810409999 hasLocation W28104099993 @default.

• next