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- W2810457622 endingPage "871" @default.
- W2810457622 startingPage "871" @default.
- W2810457622 abstract "Current evidence supports the use of probiotics in preterm neonates for prevention of necrotizing enterocolitis, mortality and late onset sepsis. Despite the strong evidence, the uptake of this intervention has not been universal due to concerns including probiotic sepsis, pro-inflammatory response and transmission of antibiotic resistance. Critically ill extremely preterm neonates with potentially compromised gut integrity are at higher risk of probiotic sepsis due to translocation. In most countries, probiotics are sold as food supplements with poor quality control. The traditional definition of probiotics as “live microorganisms” has been challenged as many experts have questioned the importance of viability in the context of the beneficial effects of probiotics. Paraprobiotics (ghost probiotics), are defined as non-viable microbial cells (intact or broken) or crude cell extracts (i.e., with complex chemical composition), which, when administered (orally or topically) in adequate amounts, confer a benefit on the human or animal consumer. Current evidence indicates that paraprobiotics could be safe alternatives to probiotics in preterm neonates. High-quality pre-clinical and clinical studies including adequately powered randomised controlled trials (RCTs) are warranted in preterm neonates to explore this new frontier." @default.
- W2810457622 created "2018-07-10" @default.
- W2810457622 creator A5010934090 @default.
- W2810457622 creator A5016946221 @default.
- W2810457622 creator A5091103116 @default.
- W2810457622 date "2018-07-05" @default.
- W2810457622 modified "2023-10-16" @default.
- W2810457622 title "Para-probiotics for Preterm Neonates—The Next Frontier" @default.
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- W2810457622 cites W1504746162 @default.
- W2810457622 cites W1519229946 @default.
- W2810457622 cites W1616059760 @default.
- W2810457622 cites W1801373898 @default.
- W2810457622 cites W1877250434 @default.
- W2810457622 cites W1892607853 @default.
- W2810457622 cites W1941532421 @default.
- W2810457622 cites W1963912646 @default.
- W2810457622 cites W1965661198 @default.
- W2810457622 cites W1972343092 @default.
- W2810457622 cites W1974424681 @default.
- W2810457622 cites W1975038056 @default.
- W2810457622 cites W1976443438 @default.
- W2810457622 cites W1976456562 @default.
- W2810457622 cites W1977968890 @default.
- W2810457622 cites W1978000678 @default.
- W2810457622 cites W1978146503 @default.
- W2810457622 cites W1981376846 @default.
- W2810457622 cites W2007448516 @default.
- W2810457622 cites W2007807635 @default.
- W2810457622 cites W2013422468 @default.
- W2810457622 cites W2014907915 @default.
- W2810457622 cites W2020864593 @default.
- W2810457622 cites W2031487885 @default.
- W2810457622 cites W2035673458 @default.
- W2810457622 cites W2036112311 @default.
- W2810457622 cites W2044599763 @default.
- W2810457622 cites W2046435267 @default.
- W2810457622 cites W2063820438 @default.
- W2810457622 cites W2067218716 @default.
- W2810457622 cites W2067548751 @default.
- W2810457622 cites W2070798058 @default.
- W2810457622 cites W2073900522 @default.
- W2810457622 cites W2075816488 @default.
- W2810457622 cites W2080339969 @default.
- W2810457622 cites W2081135453 @default.
- W2810457622 cites W2082254588 @default.
- W2810457622 cites W2084785540 @default.
- W2810457622 cites W2090114316 @default.
- W2810457622 cites W2090210288 @default.
- W2810457622 cites W2090546766 @default.
- W2810457622 cites W2094440904 @default.
- W2810457622 cites W2095625773 @default.
- W2810457622 cites W2096832134 @default.
- W2810457622 cites W2103403925 @default.
- W2810457622 cites W2105743362 @default.
- W2810457622 cites W2114151609 @default.
- W2810457622 cites W2117742527 @default.
- W2810457622 cites W2127935875 @default.
- W2810457622 cites W2131484195 @default.
- W2810457622 cites W2132241088 @default.
- W2810457622 cites W2137273627 @default.
- W2810457622 cites W2138135196 @default.
- W2810457622 cites W2140648654 @default.
- W2810457622 cites W2141149342 @default.
- W2810457622 cites W2143034146 @default.
- W2810457622 cites W2143868536 @default.
- W2810457622 cites W2148132435 @default.
- W2810457622 cites W2152692619 @default.
- W2810457622 cites W2157213020 @default.
- W2810457622 cites W2158755442 @default.
- W2810457622 cites W2158859130 @default.
- W2810457622 cites W2160829089 @default.
- W2810457622 cites W2161870183 @default.
- W2810457622 cites W2165457181 @default.
- W2810457622 cites W2170210827 @default.
- W2810457622 cites W2185956626 @default.
- W2810457622 cites W2288212279 @default.
- W2810457622 cites W2296060532 @default.
- W2810457622 cites W2507454837 @default.
- W2810457622 cites W2512327724 @default.
- W2810457622 cites W2588681363 @default.
- W2810457622 cites W2609753056 @default.
- W2810457622 cites W2616265506 @default.
- W2810457622 cites W2744957625 @default.
- W2810457622 cites W2753844555 @default.
- W2810457622 cites W4235469056 @default.
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- W2810457622 doi "https://doi.org/10.3390/nu10070871" @default.
- W2810457622 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6073938" @default.
- W2810457622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29976885" @default.
- W2810457622 hasPublicationYear "2018" @default.
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